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GEN highlights increasing use of digital gene expression profiling
A novel technique for carrying out gene-expression profiling is set to challenge the market dominance of the current, widely used methodology, reports Genetic Engineering & Biotechnology News (GEN).   view more (2009-04-06)

Gene expression in labor; and more — press release from PLoS Medicine
A Research Article, Perspective and e-Letter all published today discuss the use of microarrays to discover genes involved in childbirth. The three papers highlight the complexity of such gene expression analyses but also how crucial it is to make original data available for reanalysis.   view more (2006-06-13)

Core needle biopsy gives an accurate picture of gene expression in whole tumor
The gene expression profile detected in the core needle biopsy of a breast tumour is representative of gene expression in the whole tumour.   view more (2006-08-21)

Gene Test Could Reduce Unnecessary Treatment For Women With Breast Cancer (pp 340, 362)
In this week's issue of THE LANCET, US researchers describe how gene expression profiles could determine whether or not women with breast cancer would respond to docetaxel treatment. Women who are likely to be resistant to the drug could be given alternative treatment. Chemotherapy or hormonal treatment after surgery for breast cancer is crucial... view more... (2003-07-30)

Conserved gene expression reveals our 'inner fish'
A study of gene expression in chickens, frogs, pufferfish, mice and people has revealed surprising similarities in several key tissues.   view more (2009-04-16)

Roles of S100A2 and p63 in the carcinogenesis of esophageal squamous cell carcinoma
As a member of the S100 family, S100A2 is considered a candidate tumor-suppressor gene. Recently, p63 gene, a new member of the p53 gene family, has been studied in the fields of tumorigenesis, cell apoptosis and tissue growth.   view more (2009-09-17)

Different but equal: Settling the dosage compensation debate
Independent research papers from Dr. Peter Becker (Munich, Germany) and Dr. Mitzi Kuroda (Boston, MA) in the October 1 issue of Genes & Development delineate the mechanism of X-chromosome dosage compensation in Drosophila.   view more (2005-10-03)

Gene-expression profiling of the effects of liver toxins
Gene-expression data from liver tissue or whole blood can be used to classify histopathologic differences in the effects of hepatotoxins. It is hoped that these findings, published in BioMed Central's open access journal, Genome Biology, will lead to a more precise way of defining the potential hepatotoxicity of new compounds.    view more (2008-06-20)

New study shows that therapeutic gene expression can be sustainable for 1 year
Researchers at the Board of Governors Gene Therapeutics Research Institute at Cedars-Sinai Medical Center have shown for the first time that it is possible to sustain therapeutic gene expression in the central nervous system for up to a year, even in the presence of an anti-viral immune response mechanism that is normally present in humans.   view more (2007-10-26)

"Sloppy Genes" Behave Like Their Neighbours: New Findings Reveal That The Regulation Of Gene Expression Is Much Less Strictly Controlled Than Was Previously Thought
The inaugural issue of Journal of Biology features groundbreaking research that challenges the traditional view of how genes are controlled. Our current understanding of gene expression, the fundamental process by which proteins are made from the instructions encoded in DNA, is that the process is tightly controlled so that the correct amount of... view more... (2002-06-13)

Food cue-related brain activity linked to obesity?
A unique pattern of gene expression observed in rats may be linked to a conditioned desire for food and excessive food intake, an article published today in BMC Biology suggests.   view more (2007-04-27)

Researchers find an evolutionarily preserved signature in the primate brain
Researchers have determined that there are hundreds of biological differences between the sexes when it comes to gene expression in the cerebral cortex of humans and other primates.   view more (2008-06-20)

Researchers identify gene associated with muscular dystrophy-related vision problems
Skeletal muscle disease and vision deficits might seem unrelated, but a frog model of muscular dystrophy shows it is not such a leap.   view more (2009-04-21)

New tool probes function of rice genes
A new tool for investigating the rice genome has been developed by researchers at UC Davis led by Pamela Ronald, professor of plant pathology.   view more (2008-10-09)

Early-stage gene transcription creates access to DNA
A gene contained in laboratory yeast has helped an international team of researchers uncover new findings about the process by which protein molecules bind to control sequences in genes in order to initiate gene expression, according to findings reported in the journal Nature.   view more (2008-10-07)

Insect gene expression responds to diet
Cabbage looper caterpillars (Trichoplusia ni) are able to alter the expression of genes associated with metabolism, homeostasis and immunity in response to feeding on plants carrying bacteria.   view more (2009-05-07)

A new take on growth factor signaling in tamoxifen resistance
Differences in growth factor (GF) signaling may cause the poor prognosis in some breast cancer cases. A new study, published in the open access journal BMC Medical Genomics, suggests that some estrogen receptor-positive breast cancers respond poorly to tamoxifen because of increased GF signaling.   view more (2009-06-24)

Turn-ons and turn-offs for neurons
Our brain consists of billions of nerve cells enabling to learn, remember and reason. Every time we think and experience, touch, smell or fear, millions of neurons in our brain becomes active.   view more (2007-06-20)

CDX2 — A protein that promotes leukemia
Researchers from Harvard Medical School, Boston, have found that most individuals with acute myeloid leukemia (AML) inappropriately express a protein known as CDX2 in their leukemic cells.   view more (2007-03-08)

Schizophrenia and bipolar disorder could have similar genetic causes (pp 758, 798)
Issue 6 September 2003 Embargoed 0001 h (London time) 5 September 2003. Authors of a study in this week's issue of THE LANCET provide strong evidence that schizophrenia and bipolar disorder have a similar genetic cause arising from reduced expression of genes responsible for myelin development of the central nervous system. Schizophrenia and... view more... (2003-09-03)
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