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Scientists identify gene that may contribute to improved rice yield
A team of scientists, including Penn State Distinguished Professor of Biology Hong Ma, has identified a gene in rice that controls the size and weight of rice grains.   view more (2008-09-29)

Channels of cellular communication
A potential new channel of communication between different cellular compartments has been discovered by researchers at the University of Leeds. Dr Jim Deuchars` group show how the protein P2X7, which forms a channel known to mediate ion movements between cells and their external environment, may... view more (2002-11-08)

Food cue-related brain activity linked to obesity?
A unique pattern of gene expression observed in rats may be linked to a conditioned desire for food and excessive food intake, an article published today in BMC Biology suggests.   view more (2007-04-27)

Cranberries can treat herpes
Alpine cranberries have significant biological activity that can help to combat herpes virus type II (HSV-2) infection, one of the most common viral infections in humans, writes Emma Dorey in Chemistry & Industry.   view more (2004-10-15)

Cancer-killing viruses influence tumor blood-vessel growth
Viruses genetically designed to kill cancer cells offer a promising strategy for treating incurable brain tumors such as glioblastoma, but the body's natural defenses often eliminate the viruses before they can eliminate the tumor.   view more (2008-06-11)

Jefferson Scientists See Breast Cancer Gene Activity from Outside the Body
Researchers at Jefferson Medical College and Jefferson's Kimmel Cancer in Philadelphia have used PET imaging to see hyperactive cancer genes inside breast tumors in laboratory animals, marking the first time such gene activity has been observed from outside the body.   view more (2007-11-29)

New methods offer insight into regulatory DNA
Through the Human Genome Project, the HapMap Project and other efforts, we are beginning to identify genes that are modified in some diseases. More difficult to measure and identify are the regulatory regions in DNA - the 'managers' of genes - that control gene activity and might be important in... view more (2005-12-16)

Drugs without side effects
Developing new medications is costly and complex. Gene expression analysis aids in the early detection of the toxicity and effectiveness of new medicines. The method paves the way for customized medical treatment where side effects will be cancelled out. Pharmaceutical research is a long, tedious... view more (2004-02-26)

Key to lung cancer chemo resistance revealed
Scientists at Johns Hopkins have discovered how taking the brakes off a "detox" gene causes chemotherapy resistance in a common form of lung cancer.   view more (2006-10-11)

A molecular map for aging in mice
Researchers at the National Institute of Aging and Stanford University have used gene arrays to identify genes whose activity changes with age in 16 different mouse tissues.   view more (2007-11-29)

Researchers discover gene mutation thought to control energy levels
This study focused on the gene for AMPK (adenosine monophosphate-activated protein kinase), which controls the amount of energy in our cells by becoming active when fuel stores start to deplete, such as during exercise.   view more (2007-09-19)

The importance of gene regulation for common human disease
A new study published in Nature Genetics on Sunday 16 September 2007 show that common, complex diseases are more likely to be due to genetic variation in regions that control activity of genes, rather than in the regions that specify the protein code.   view more (2007-09-17)

Huntington's disease study shows animal models on target
An international team of researchers has published a benchmark study showing that gene expression in several animal models of Huntington's Disease (HD) closely resembles that of human HD patients.   view more (2007-08-01)

How plants remember winter, in order to flower in spring
Scientists at the John Innes Centre (JIC) Norwich (1), have discovered the molecular change that allows plants to remember winter. Many plants need a cold period (3-8 weeks at 4o - 8oC) early in their growth to stimulate them to flower, this is called vernalisation, and without a suitable cold... view more (2004-01-06)

Variants in three estrogen-related genes linked to Parkinson's disease in women
Mayo Clinic researchers have discovered a possible connection between increased risk for Parkinson's disease and variants in three genes that control estrogen production and activity in the body.   view more (2006-04-05)

Ago2 and hematopoiesis
Argonaute 2 (Ago2) is unique among its family: It is the only one of the four mammalian Argonaute proteins that exhibits endonuclease "slicer" activity (facilitation of miRNA-guided cleavage of target mRNA).   view more (2007-07-12)

Protein plays broader role than originally thought in neurofibromatosis
Neurofibromatosis type I is a common genetic disorder in which tumors grow along certain types of nerves and can also affect other tissues such as bone, heart, and skin.   view more (2006-08-11)

Helping Tomatoes Cope With Stress May Be Good For Us
Scientists at the John Innes Centre (JIC)(1) and Institute of Food Research (IFR)(2), Norwich, have today reported the discovery and use of a gene that may help protect plants and humans against disease. The gene (HQT) was identified in tomato and is responsible for producing an antioxidant called... view more (2004-04-26)

Unraveling where chimp and human brains diverge
Six million years ago, chimpanzees and humans diverged from a common ancestor and evolved into unique species.   view more (2006-11-14)

Gene therapy to lower blood pressure just enough
A newly developed virus that introduces a blood pressure-lowering gene into cells and enables that gene to maintain blood pressure at healthy levels for four months promises to take gene therapy for the disorder a step closer to reality.   view more (2005-09-28)

Newly Identified Gene Activated In 80% Of Breast Cancer Patients
New research, published this week in Breast Cancer Research, could provide a genetic explanation for breast cancer. A George Washington University Medical Center team, led by Patricia Berg, has discovered that the gene BP1 is activated in 80% of breast cancer patients. The researchers believe that... view more (2003-04-25)

Evolutionary battle scars' identify enhanced antiviral activity
Rapid evolution of a protein produced by an immunity gene is associated with increased antiviral activity in humans, a finding that suggests evolutionary biology and virology together can accelerate the discovery of viral-defense mechanisms.   view more (2008-01-25)

Breakthrough in national diseases: Common factor behind myocardial infarction, rheumatism and MS
A common gene variant has been identified as the risk factor behind a number of common diseases by research scientists at Karolinska Institutet and the Centre for Molecular Medicine (CMM), Stockholm, Sweden. Up to a quarter of the population could be affected.   view more (2005-04-08)

Jefferson scientists show gene reverts cancer genes to normal, predicts breast cancer prognosis
Scientists at the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia have shown that the activity of a gene that commandeers other cancer-causing genes, returning them to normal, can predict the prognosis of an individual with breast cancer.   view more (2006-11-01)

How Rett Syndrome mutation targets the brain
Researchers have pinpointed why mutations that cause Rett Syndrome (RTT)-among the leading causes of mental retardation in females-specifically target the brain rather than other body tissues.   view more (2006-10-19)
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