Identify genetic markers to predict male fertility
The diagnosis of male fertility is usually performed through the observation of the sperm in the microscope. However, a normal quality semen does not guarantee an adequate fertility. In fact, there is a considerable proportion of cases of unexplained infertility and data suggest that abnormal sperm function may have a genetic or molecular origin. View More (2012-05-24)
Stem cell research paves way for progress on dealing with Fragile X retardation
Researchers at the Hebrew University of Jerusalem have achieved, for the first time, the generation of neuronal cells from stem cells of Fragile X patients. View More (2012-05-23)
Scientists unravel role of fusion gene in prostate cancer
Up to half of all prostate cancer cells have a chromosomal rearrangement that results in a new "fusion" gene and formation of its unique protein -- but no one has known how that alteration promotes cancer growth. View More (2012-05-23)
New technique reveals unseen information in DNA code
Imagine reading an entire book, but then realizing that your glasses did not allow you to distinguish "g" from "q." What details did you miss? View More (2012-05-18)
Protein RAL associated with aggressive characteristics in prostate, bladder and skin cancers
We have known for years that when the proteins RalA and RalB are present, cells in dishes copy toward aggressive forms of cancer. View More (2012-05-18)
Finnish researchers identified the cause for LGL leukemia
LGL leukemia is a relatively rare, malignant blood disease of the mature T-cells and, in many cases, it is related to autoimmune diseases such as rheumatoid arthritis. View More (2012-05-17)
Revised glioblastoma classification should improve patient care
Radiation oncology researchers have revised the system used by doctors since the 1990s to determine the prognosis of people with glioblastoma, which is the most devastating of malignant brain tumors. View More (2012-05-17)
Children with rare, incurable brain disease improve after gene therapy
Using gene transfer techniques pioneered by University of Florida faculty, Taiwanese doctors have restored some movement in four children bedridden with a rare, life-threatening neurological disease. View More (2012-05-17)
Mice with big brains provide insight into brain regeneration and developmental disorders
Scientists at the Ottawa Hospital Research Institute (OHRI) and the University of Ottawa (uOttawa) have discovered that mice that lack a gene called Snf2l have brains that are 35 per cent larger than normal. View More (2012-05-16)
A marker in the lining of the lungs could be useful diagnostic technique for lung cancer screening
The most recent research released in June's Journal of Thoracic Oncology says molecular biomarkers in the tissue and fluid lining the lungs might be an additional predictive technique for lung cancer screening. View More (2012-05-16)
Children's brain tumors more diverse than previously believed
Paediatric brain tumours preserve specific characteristics of the normal cells from which they originate - a previously unknown circumstance with ramifications for how tumour cells respond to treatment. View More (2012-05-15)
CNIO scientists successfully test the first gene therapy against aging-associated decline
A number of studies have shown that it is possible to lengthen the average life of individuals of many species, including mammals, by acting on specific genes. View More (2012-05-15)
Genetic test identifies eye cancer tumors likely to spread
Researchers at Washington University School of Medicine in St. Louis have developed a genetic test that can accurately predict whether the most common form of eye cancer will spread to other parts of the body, particularly the liver. View More (2012-05-15)
Early biomarker for pancreatic cancer identified
Researchers at the University of California, San Diego School of Medicine and Moores Cancer Center have identified a new biomarker and therapeutic target for pancreatic cancer, an often-fatal disease for which there is currently no reliable method for early detection or therapeutic intervention. View More (2012-05-15)
Researchers identify key genes and prototype predictive test for schizophrenia
An Indiana University-led research team, along with a group of national and international collaborators, has identified and prioritized a comprehensive group of genes most associated with schizophrenia that together can generate a score indicating whether an individual is at higher or lower risk of developing the disease. View More (2012-05-15)
Delivery system for gene therapy may help treat arthritis
A DNA-covered submicroscopic bead used to deliver genes or drugs directly into cells to treat disease appears to have therapeutic value just by showing up, researchers report. View More (2012-05-15)
Molecular subtypes and genetic alterations may determine response to lung cancer therapy
Cancer therapies targeting specific molecular subtypes of the disease allow physicians to tailor treatment to a patient's individual molecular profile. View More (2012-05-14)
Genetic predictor of breast cancer response to chemotherapy
Chemotherapy is a major first line defense against breast cancer. However a patient's response is often variable and unpredictable. View More (2012-05-11)
Discovery of a gene that causes Joubert Syndrome
C5ORF42 was identified as the gene that causes Joubert Syndrome in a number of families in the Lower St. Lawrence region of Quebec where the causal gene had remained unknown since the initial description of the syndrome in 1969. View More (2012-05-11)
Researchers Use Light to Switch On Gene Expression
Imagine being able to control genetic expression by flipping a light switch. Researchers at North Carolina State University are using light-activated molecules to turn gene expression on and off. View More (2012-05-11)
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