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metaGen and RNAx Announce Target Validation Agreement metaGen Pharmaceuticals and RNAx announced today the signing of a target validation agreement. Under the terms of the agreement RNAx provides metaGen with access to RNA interference validation technology (RNAi). metaGen will employ this technology to validate proprietary gene targets relevant for cancer and will own the derived results. Financial... view more... (2003-03-25)
A single gene makes the chicken a victim Feather pecking is a common and serious behavioural disorder in laying hens around the world. The chickens peck and pull the feathers of their victims, and this may lead to cannibalism. Now a group of researchers under the lead of Per Jensen, Professor of ethology at Linköping University have shown that the risk of becoming a victim is... view more... (2004-10-04)
New gene for rheumatism identified A genetic variant that can explain the occurrence of a type of rheumatic disorder called SLE has been identified by a research team at Uppsala University, Sweden. The team, led by Associate Professor Marta Alarc'łn at the Rudbeck Laboratory, is presenting its finding in the latest issue of the scientific journal Nature Genetics. Nearly 6,000... view more... (2002-10-29)
Genetic variation helps to understand predisposition to schizophrenia Scientists have provided new insight into how a gene is related to schizophrenia. view more (2007-08-10)
Novel structure proteins could play a role in apoptosis Isoforms from Novel Structure Proteins (NSP), a new family of genes discovered by researchers in the Sbarro Institute for Cancer Research and Molecular Medicine in Temple University's College of Science and Technology, could be involved in apoptosis or programmed cell death. view more (2008-07-25)
Another gene rearrangement involved in prostate cancer identified Researchers at the University of Michigan Medical School have identified a third gene involved in prostate cancer, expanding their groundbreaking announcement, published last October in Science, that the majority of prostate cancers carry a malignancy-inducing fusion of genes never before seen in solid tumors. view more (2006-04-04)
Alpha-fetoprotein can affect the development of rat colons? Mammalian alpha-fetoprotein (AFP) is a single-chain glycoprotein and altered serum AFP levels have been observed concurrent with aberrant growth manifestations in some congenital defects and cancer. view more (2009-04-17)
Basic work on E. coli identifies two new keys to regulation of bacterial gene expression The cellular process of transcription, in which the enzyme RNA polymerase constructs chains of RNA from information contained in DNA, depends upon previously underappreciated sections of both the DNA promoter region and RNA polymerase, according to work done with the bacterium E. coli. view more (2006-06-19)
Central and peripheral signals set the circadian liver clock Anyone who has experienced jet lag will understand the importance of a smooth-running circadian clock. Crossing time zones decouples our biological rhythms from the natural cycle of light and dark we're used to. view more (2007-01-30)
Gladstone scientists prove neurons produce Alzheimer's-linked apolipoprotein E A question long debated among Alzheimer's disease researchers has been definitively answered by scientists at the Gladstone Institute of Neurological Disease in San Francisco. view more (2006-05-11)
Study provides hope that some transplant patients could live free of anti-rejection drugs People with organ transplants, resigned to a lifetime of anti-rejection drugs, may now have reason to hope for a respite, say researchers at Lucile Packard Children's Hospital and the Stanford University School of Medicine. view more (2007-08-21)
Omega fatty acid balance can alter immunity and gene expression For the past century, changes in the Western diet have altered the consumption of omega-6 fatty acids (w6, found in meat and vegetable oils) compared with omega-3 fatty acids (w3, found in flax and fish oil). view more (2009-06-01)
Toxins in cigarette smoke prevent stem cells from becoming cartilage A toxic pollutant spread by oil spills, forest fires and car exhaust is also present in cigarette smoke, and may represent a second way in which smoking delays bone healing, according to research presented today at the annual meeting of the Orthopaedic Research Society in San Francisco. view more (2008-03-04)
Protein amplification in melanoma is possible drug target Researchers have pinpointed specific gene and protein over-production in metastatic melanoma, pointing the way to a possible new drug target, according to a study published in Nature July 7. view more (2005-07-11)
Phase of clock gene expression in human leukocytes correlates with habitual sleep timing The phase of clock gene expression in leukocytes, assessed in the absence of the masking effects of light-dark and sleep-wake cycles, correlates with habitual sleep timing, according to a study published in the May 1 issue of the journal SLEEP. view more (2008-05-01)
Novel marker of colon cancer Colon cancer ranks second of all gastrointestinal malignant tumors, it is one of the leading causes of cancer-related deaths worldwide. view more (2008-10-24)
Genetic key to growth of new arteries is identified Researchers at the San Francisco VA Medical Center have uncovered part of the genetic mechanism that causes new arteries to grow in response to blocked arteries. view more (2005-12-01)
HtrA1 and resistance to chemotherapy in ovarian and gastric cancers While many cancer patients initially have a favorable response to chemotherapy for the treatment of solid tumors, resistance to treatment often develops. view more (2006-06-09)
Powerful new tool for studying brain development Scientists at St. Jude Children's Research Hospital have given investigators around the world free access to a powerful tool for studying brain development. view more (2006-03-28)
MicroRNAs grease the cell's circadian clockwork Most of our cells possess an internal clock, a group of genes displaying a cyclic expression pattern that reaches a peak once a day. view more (2009-06-01)
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