Gene Expression Current Events | Gene Expression News | 2
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A molecular map for aging in mice
Researchers at the National Institute of Aging and Stanford University have used gene arrays to identify genes whose activity changes with age in 16 different mouse tissues. view more (2007-11-29)
Fly with brain tumor may shed light on cancer causing genes
A study showing how the expression of genes changes when the brain tissue of fruit flies becomes cancerous is published this week in BMC Genomics. As the function of many of these genes is conserved across evolution, the researchers expect their results will help us to understand why human brain tumors develop. The causes of brain tumor... view more... (2004-04-14)
Which is promising as therapeutic targets in patients with biliary tract cancer? EGFR or HER2?
The epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER2) are involved in the carcinogenesis of many malignancies. view more (2009-10-16)
For some young fish, early gene expression is a clear harbinger of fated lifestyle
As juveniles, individuals of many fish species face a developmental choice that will profoundly affect their future: whether to adopt a sedentary or migratory lifestyle. view more (2006-04-18)
Cancer: Another step towards medication
The gene Myc is an important factor for the growth of organisms by cell division. It causes the production of a protein which, as a transcription factor, controls the expression of up to 15 % of all human genes. view more (2009-03-18)
Cancer signatures uncovered
A new systematic analysis of the relationship between the neoplastic and developmental transcriptome provides an outline of trends in cancer gene expression. view more (2008-08-18)
In a rare disorder, a familiar protein disrupts gene function
As reported this week in the open-access journal PLoS Biology, an international team of scientists studying a rare genetic disease has discovered that a bundle of proteins already known to be important for keeping chromosomes together also plays an important role in regulating gene expression in humans. view more (2009-05-27)
Isolation of a new gene family essential for early development
Researchers at BRIC, University of Copenhagen, have identified a new gene family (UTX-JMJD3) essential for embryonic development. The family controls the expression of genes crucial for stem cell maintenance and differentiation, and the results may contribute sig-nificantly to the understanding of the development of cancer. view more (2007-08-23)
Mayo Clinic: Gene expression profiling not quite perfected in predicting lung cancer prognosis
While there have been significant advances in the use of gene expression profiling to assess a cancer prognosis, a Mayo Clinic review and analysis of existing lung cancer studies shows that this technology has not yet surpassed the accuracy of conventional methods used to assess survival in lung cancer patients. view more (2006-11-17)
Early predictor of breast cancer aggressiveness
Physicians may be able to make early decisions on the best treatment for breast cancer, thanks to research published in Breast Cancer Research today. A gene involved in the adhesion of cells is less active in breast tumors with a poor prognosis than those that are less aggressive, researchers found. Measuring the activity of the ALCAM gene in... view more... (2004-06-24)
Newly Identified Gene Activated In 80% Of Breast Cancer Patients
New research, published this week in Breast Cancer Research, could provide a genetic explanation for breast cancer. A George Washington University Medical Center team, led by Patricia Berg, has discovered that the gene BP1 is activated in 80% of breast cancer patients. The researchers believe that this gene may offer a useful new target for early... view more... (2003-04-25)
Research elucidates mechanism by which gene expression may be altered in drug addiction
Dr. Judith A. Potashkin, Ph.D. and her colleagues at Rosalind Franklin University of Medicine and Science recently completed a study investigating one of the changes in gene expression that occurs when individuals take addictive drugs. view more (2007-09-05)
Cracking the genetic code for control of gene expression
Molecular biologists, developmental biologists and computer scientists at the Universtity of Helsinki, Finland, came together to advance towards cracking the code for how gene expression is controlled. view more (2006-01-13)
Location, location, location: Transcriptional activity and nuclear position
Dr. Mark Groudine (FHCRC) and colleagues report on their surprising characterization of changes in intranuclear organization during murine erythropoiesis. view more (2006-05-18)
Gene packaging tells story of cancer development
To decipher how cancer develops, Johns Hopkins Kimmel Cancer Center investigators say researchers must take a closer look at the packaging. view more (2008-12-05)
Jefferson scientists show gene reverts cancer genes to normal, predicts breast cancer prognosis
Scientists at the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia have shown that the activity of a gene that commandeers other cancer-causing genes, returning them to normal, can predict the prognosis of an individual with breast cancer. view more (2006-11-01)
Chronic fatigue: clues in the blood
Researchers at UNSW believe that blood may hold vital insights into what is happening in the brain of patients with chronic fatigue syndrome (CFS). view more (2007-07-09)
Balancing male fertility and disease resistance
An international collaboration of researchers, headed by Dr. Shiping Wang (Huazhong Agricultural University, China) has discovered that a single gene in rice regulates both male fertility and pathogen resistance, providing an unexpected genetic link between reproductive success and the disease resistance. view more (2006-05-08)
Huntington's disease study shows animal models on target
An international team of researchers has published a benchmark study showing that gene expression in several animal models of Huntington's Disease (HD) closely resembles that of human HD patients. view more (2007-08-01)
Large DNA microarray dataset is made publicly available by LGC and the European Bioinformatics Institute (EBI)
As the next phase of DTI's Measurements for Biotechnology (MfB) programme to 2007 gets underway, a large DNA microarray dataset generated by an LGC-led consortium during the first phase is now freely available online at ArrayExpress, a leading public repository managed by the European Bioinformatics Institute (EBI). The sharing of well-annotated... view more... (2005-02-17)
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