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PrP gene regulators could play a part in CJD susceptibility. Plus other science stories from the IAH's latest annual report The Institute for Animal Health has published its 2002 Annual Report and Accounts. The report includes the following science stories from research around the Institute. view more (2003-05-21)
Patterns on tropical marine mollusk shell mirror gene expression patterns Scientists have identified a group of genes that control the formation of shapes and colour patterns on the shell of the tropical marine mollusc referred to as 'abalone'. view more (2006-11-22)
Mean new microRNA data analysis method gives sharper results Our understanding of the importance of microRNAs in regulating gene expression is expanding, and with it our requirement for robust methods to measure their expression levels. view more (2009-06-16)
Feeling sleepy is all in your genes Genes responsible for our 24 hour body clock influence not only the timing of sleep, but also appear to be central to the actual restorative process of sleep, according to research published in the online open access journal BMC Neuroscience. view more (2007-10-18)
Drugs without side effects Developing new medications is costly and complex. Gene expression analysis aids in the early detection of the toxicity and effectiveness of new medicines. The method paves the way for customized medical treatment where side effects will be cancelled out. Pharmaceutical research is a long, tedious process. On average, it takes 12-15 years to... view more... (2004-02-26)
Cocaine-linked genes enhance behavioral effects of addiction New research sheds light on how cocaine regulates gene expression in a crucial reward region of the brain to elicit long-lasting changes in behavior. view more (2009-05-14)
Gene expression pattern could lead to improved treatment of pediatric septic shock A consortium of researchers headed by Cincinnati Children's Hospital Medical Center has discovered a gene expression pattern that could lead to improved diagnosis and treatment of pediatric septic shock - still a serious public health problem despite today's potent antibiotics and pediatric intensive care units. view more (2007-07-27)
Genetic parallels found between lung development and lung cancer For over 100 years, biologists have speculated that cancer growth shares common features with embryonic development. view more (2006-07-05)
Prediction of gene function in mammals Gene function in mammals can be quickly and reliably predicted using a high-throughput analysis of patterns of RNA expression, according to an article published today in Journal of Biology. This challenges the conventional view that tissue-specificity is the best predictor of function, and could speed up the quest to understand whole genomes, in... view more... (2004-12-02)
Human cerebellum and cortex age in very different ways Researchers have found that the two primary areas of the human brain appear to age in radically different ways: The cortex used in higher-level thought undergoes more extensive changes with age than the cerebellum, which regulates basic processes such as heartbeat, breathing and balance. view more (2005-08-02)
Mayo Clinic study finds two genes predict outcome for breast cancer patients The 2-gene expression profile of HOXB13 and IL17BR in a woman's breast cancer predicts risk of recurrence in node-negative patients treated with tamoxifen. view more (2006-04-03)
Why does aspirin increase the susceptibility of Helicobacter pylori to antimicrobials? Resent studies reported that aspirin inhibited the growth of H. pylori in a dose-dependent manner and significantly affected the activity of virulence factors of H. pylori. view more (2009-03-03)
Study identifies common flaws in oncology microarray studies A substantial percentage of microarray-based studies in oncology contain critical flaws in analysis or in their conclusions, reports a study in the January 17 issue of the Journal of the National Cancer Institute. view more (2007-01-17)
Masterminding muscle development Dr. Lizi Wu (Dana Farber Cancer Institute) and colleagues report on a critical role for one of the three mammalian mastermind genes (Maml1) in myogenesis - assigning that first biological function to the mammalian MAML Notch co-activators. view more (2006-02-28)
Researchers discover important tool in understanding differentiation in human embryonic stem cells Researchers at the University of Minnesota's Stem Cell Institute have described how an existing genetic tool can be used to study how human embryonic stem cells differentiate. The research appears in the November 2007 issue of Experimental Biology and Medicine. view more (2007-10-25)
A brave new "old world" of RNA A new function for RNA, which further elucidates how genes are expressed and regulated, is described on the 25th of November issue of the journal Nature. view more (2004-11-22)
Gene silencing technique offers new strategy for treating, curing disease A new technique aimed at directly controlling the expression of genes by turning them on or off at the DNA level could lead to drugs for the treatment or cure of many diseases, say researchers at UT Southwestern Medical Center. view more (2005-08-01)
MicroRNAs Can Be Tumor Suppressors University of Virginia researchers have discovered that microRNAs, a form of genetic material, can function as tumor suppressors in laboratory studies. view more (2007-04-26)
Tolerance to inhalants may be caused by changes in gene expression Changes in the expression of genes may be the reason why people who abuse inhalants, such as spray paint or glue, quickly develop a tolerance, biologists at The University of Texas at Austin have discovered. view more (2007-10-18)
Researchers identify another potential biomarker Researchers from Boston University School of Medicine (BUSM) have demonstrated that a recently discovered class of molecule called microRNA (miRNAs), regulate the gene expression changes in airway cells that occur with smoking and lung cancer. view more (2009-01-14)
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