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MIT: Prenatal arsenic exposure detected in newborns
MIT researchers have found that the children of mothers whose water supplies were contaminated with arsenic during their pregnancies harbored gene expression changes that may lead to cancer and other diseases later in life.   view more (2007-11-26)

Gene regulation in humans is closer than expected to simple organisms
Gene networks are some of the most basic features of a living organism. An external or internal stimulus activates some genes, which in turn control others genes whose activity turns on or off various biological processes (such as the cell cycle, energy production, DNA repair, cellular suicide etc).   view more (2007-08-30)

Genetics of muscular dystophy
Various forms of human muscular dystrophy result from mutations in genes encoding proteins of the nuclear envelope. A new paper in the February 15th issue of G&D reveals how.   view more (2006-02-15)

Loneliness is a molecule
It's already known that a person's social environment can affect their health, with those who are socially isolated-that is, lonely suffering from higher mortality than people who are not.   view more (2007-09-13)

miR-196a promotes the metastases of tumors
MicroRNAs are small RNA molecules of 20-25 nucleotides length, regulating gene expression by inhibition of transcription or translation of proteins.   view more (2009-05-13)

Will IVF work for a particular patient? The answer may be found in her blood
For the first time, researchers have been able to identify genetic predictors of the potential success or failure of IVF treatment in blood.   view more (2009-07-01)

Gene signature assesses breast cancer outcomes
A test that looks at the expression of 70 genes linked to breast cancer can accurately assess a patient's risk of recurrence or death.   view more (2006-09-06)

Chronic stress alters our genetic immune response
Most people would agree that stress increases your risk for illness and this is particularly true for severe long-term stresses, such as caring for a family member with a chronic medical illness.   view more (2008-08-27)

Gene expression findings a step toward better classification and treatment of juvenile arthritis
Scientists have discovered gene expression differences that could lead to better ways to classify, predict outcome, and treat juvenile idiopathic arthritis (JIA).   view more (2009-06-30)

More evidence mammals, fruit flies share make-up on function of biological clocks
A study by researchers at New York University and the University of London offers additional evidence that mammals and fruit flies share a common genetic makeup that determines the function of their internal biological clocks. The study appears in the latest issue of Current Biology.   view more (2006-03-07)

Plastics in common household items may cause fertility defects
The contaminant bisphenol-A (BPA)—widely used to make many plastics found in food storage containers and dental products—can have long-term effects in female development, according to a recent study by Yale School of Medicine researchers.   view more (2007-02-15)

Shelf-Life Science: Good Genes Could Stop Broccoli Going Bad
Broccoli is one of western Europe`s most popular and widely consumed vegetables. However, its shelf life is restricted to about 5 days at room temperature, making distribution and storage of the product difficult. Recent research presented today at the Society for Experimental Biology conference in Swansea could help us understand the genetics of... view more... (2002-04-10)

Towards predicting late-stage radiation toxicity
Radiation is a brutal and in many cases necessary part of cancer therapy. More 50% of cancer patients receive radiotherapy as part of their treatment, and many experience concurrent negative side effects.   view more (2006-10-31)

Suppression of FOXO1a gene might kill resistant ARMS tumors
The loss of function of a gene called FOXO1a plays an important role in the development of the most common cancer of soft tissues in children, and restoring the function of that gene in cancer cells suppresses that cancer.   view more (2005-09-22)

Novel mechanism of taxane resistance
Research Associate Chih-Jian Lih and others working in the laboratory of Dr. Stanley N. Cohen at Stanford University have pinpointed a gene that affects human cancer cells' sensitivity to chemotherapy-an important finding in the effort to increase the effectiveness of chemotherapy.   view more (2006-07-17)

Teamwork between 2 key proteins necessary for normal development and regulation of red blood cells
Virginia Commonwealth University researchers studying hemoglobin genes, mutations of which play a role in genetic blood disorders like sickle cell anemia and beta-thalassemia, have identified two proteins that are responsible for regulating overlapping groups of genes during the development of red blood cells.   view more (2007-08-07)

Throwing the micro switch: MicroRNA may link smoking risk gene to neurobiology of addiction
During the past several years, significant progress has been made in identifying susceptibility genes for nicotine dependence through genetic linkage and association analyses.   view more (2009-04-23)

Resistance exercise resets the body clock
Resistance exercise may directly reset the body clocks in skeletal muscle, according to research published in Genome Biology this week. This result may partly explain how exercising early in the day helps jet-lagged bodies readjust to their new time zone. Many processes in the body vary in a 24-hour rhythm called the circadian rhythm. These... view more... (2003-09-24)

Gene expression test reveals ER and HER-2 status of breast tumors
Two critical characteristics of breast cancer that are important to treatment can be identified by measuring gene expression in the tumor, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in Lancet Oncology online.   view more (2007-02-15)

UNMC researchers help make diagnostic breakthrough with Burkitt lymphoma; study detailed in New England Journal of Medicine
An international research study involving the University of Nebraska Medical Center, the National Cancer Institute and 10 other institutions has successfully identified the gene expression signature for Burkitt lymphoma.   view more (2006-06-12)
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