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Deep sequencing study reveals new insights into human transcriptome
In a collaborative project scientists from the Max-Planck-Institute for Molecular Genetics in Berlin (MPI MolGen), Germany and Genomatix with a business in Munich, Germany and Ann Arbor, MI, USA, applied next generation sequencing and analysis methods to generate an unprecedented view at the human transcriptome. view more (2008-07-09)
Balancing male fertility and disease resistance
An international collaboration of researchers, headed by Dr. Shiping Wang (Huazhong Agricultural University, China) has discovered that a single gene in rice regulates both male fertility and pathogen resistance, providing an unexpected genetic link between reproductive success and the disease resistance. view more (2006-05-08)
New Piece Found in the Puzzle of Epigenetics
A team of scientists led by Professor Dirk Eick of Helmholtz Zentrum München has identified the enzyme TFIIH kinase as an important factor in the epigenetic regulation of the cell nucleus enzyme RNA polymerase II. view more (2009-06-17)
CSHL researchers map changing epigenetic modifications that enable transposons to run amok
Much like cancer cells, plant cells grown for a long time outside of their normal milieu, in culture dishes, have highly unstable genomes. view more (2008-12-11)
Abnormal glutamine repeats interfere with key transcription factor, leading to neurodegeneration
Although repeating sequences of three nucleotides encoding some of the bodies' 20 amino acids are a normal part of protein composition, abnormal expansion of trinucleotide repeats is the known cause of multiple inherited neurodegenerative disorders, including Huntington disease. view more (2007-11-14)
Abnormal 'editing' of gene messages may be a cause of lupus
Researchers at Wake Forest University have uncovered evidence that the abnormal "editing" of gene messages in a type of white blood cell may be behind the development of lupus. view more (2008-05-20)
Cancer-causing gut bacteria exposed
Normal gut bacteria are thought to be involved in colon cancer but the exact mechanisms have remained unknown. Now, scientists from the USA have discovered that a molecule produced by a common gut bacterium activates signalling pathways that are associated with cancer cells. view more (2008-09-22)
Alzheimer's gene identified: study
An international effort led by scientists at the University of Toronto, Columbia University and Boston University has isolated another gene responsible for Alzheimer's disease. view more (2007-01-15)
Well-fed robins could be lonely at Christmas
The North Wind doth blow, And we shall have snow, And what will poor robin do then, Poor thing? (Anon) He may starve or freeze to death if he has not managed to find enough food before the snow falls. Small birds such as robins need to carry fat reserves to keep them warm. They face a dilemma each winter, as they need to spend... view more... (2002-12-09)
Early Promise Of New Treatment For Type 2 Diabetes (p 824)
Authors of a pilot study in this week's issue of THE LANCET suggest that a naturally occurring intestinal hormone could be beneficial for the future treatment of type 2 diabetes. Type 2 diabetes affects an estimated 10% of adults over 60 years of age, and has recently been reported in teenage children. Treatment for the disorder usually includes... view more... (2002-03-06)
Tiny RNA molecules fine-tune the brain's synapses
Non-coding regions of the genome - those that don't code for proteins - are now known to include important elements that regulate gene activity. view more (2006-01-19)
Changes to DNA linked to diabetes
Genes that regulate the energy consumption of cells have a different structure and expression in type II diabetics than they do in healthy people, according to a new study from the Swedish medical university Karolinska Institutet published in Cell Metabolism. view more (2009-09-02)
Snoozing worms help Penn researchers explain the evolution of sleep
The roundworm C. elegans, a staple of laboratory research, may be key in unlocking one of the central biological mysteries: why we sleep. Researchers at the University of Pennsylvania School of Medicine report in this week's advanced online edition of Nature that the round worm has a sleep-like state, joining most of the animal kingdom in... view more... (2008-01-14)
Advance Notice: Lords Committee to report on complementary and alternative medicine (CAM)
The House of Lords Science and Technology Committee will publish its Report on Complementary and Alternative Medicine with a Press Briefing on Tuesday 28 November at 11.00am. In light of the high levels of use of CAM therapies in the UK, the Report examines various aspects of CAM and makes wide ranging recommendations. Subjects covered include:... view more... (2000-11-22)
Discovering the secret code behind photosynthesis
Scientists from Queen Mary, University of London have discovered that an ancient system of communication found in primitive bacteria, may also explain how plants and algae control the process of photosynthesis. view more (2009-02-25)
Mouse protein points to memory pill for the old
A drug to aid learning and memory in the elderly may be possible as a result of work being carried out at the Wolfson Institute for Biomedical Research at University College London. A team led by Dr Karl Peter Giese, of the department of learning and memory, is looking at the molecular and cellular mechanisms underlying memory - not so much the... view more... (2000-04-10)
Neural stem cell gene plays crucial role in eye development
Scientists at the University of North Carolina at Chapel Hill have demonstrated that normal development of the eye requires the right amount of a neural stem cell gene be expressed at the right time and place. view more (2006-05-16)
Researchers discover mechanism of insulin production that can lead to better treatment for diabetes
How a specific gene within the pancreas affects secretion of insulin has been discovered by researchers from the Hebrew University of Jerusalem, in collaboration with Japanese and American universities. view more (2009-11-13)
Gene patenting -- steep cost for health care and patients
The drug trastuzumab (Herceptin) is used to treat HER2-positive breast cancer (a type of breast cancer that overexpresses the HER2 gene and accounts for about 25% of all breast cancers). view more (2007-05-08)
Experimental Parkinson's therapy may have robust weight-loss effect
A growth factor used in clinical experiments to rescue dying brain cells in Parkinson patients may cause unwanted weight loss if delivered to specific areas of the brain, according to University of Florida researchers in the March online edition of Molecular Therapy. view more (2009-03-25)
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