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Search for the 'on' switches may reveal genetic role in development and disease
A new resource that identifies regions of the human genome that regulate gene expression may help scientists learn about and develop treatments for a number of human diseases, according to researchers at Duke's Institute for Genome Sciences & Policy (IGSP). view more (2008-01-25)
Teamwork between 2 key proteins necessary for normal development and regulation of red blood cells
Virginia Commonwealth University researchers studying hemoglobin genes, mutations of which play a role in genetic blood disorders like sickle cell anemia and beta-thalassemia, have identified two proteins that are responsible for regulating overlapping groups of genes during the development of red blood cells. view more (2007-08-07)
Epigenetic research uncovers new targets for modification enzymes
Enzymes regulating genetic expression can be just as important as the genome itself, increasing evidence shows. The expanding field of epigenetics focuses on the multiple influences on DNA and surrounding molecules that determine whether genes are turned on or off during development and disease processes. view more (2008-04-28)
How nature tinkers with the cellular clock
The life of a cell is all about growing and dividing at the right time. That is why the cell cycle is one of the most tightly regulated cellular processes. view more (2006-09-28)
First gene therapy for heart failure offered at NewYork-Presbyterian/Columbia
Could injecting a gene into a patient with severe heart failure reverse their disabling and life-threatening condition? Physician-scientists are setting out to answer that question in a first-ever clinical trial of gene therapy to treat severe heart failure. view more (2008-06-19)
Study finds value in 'junk' DNA
For about 15 years, scientists have known that certain "junk" DNA -- repetitive DNA segments previously thought to have no function -- could evolve into exons, which are the building blocks for protein-coding genes in higher organisms like animals and plants. view more (2008-10-17)
Rushing fireball developed its own form of sugar digestion
Microbiologists from Wageningen have discovered a strange form of digestion in an exotic microorganism. The rushing fireball, Latin name Pyrococcus furiosus, has reinvented the wheel for several steps of sugar digestion. Pyrococcus furiosus, which was discovered 15 years ago on an Italian volcanic island, digests sugar somewhat differently from... view more... (2002-04-18)
Effects of aging in stem cells
There is little disagreement that the body's maintenance and repair systems deteriorate with age, even as there is plenty of disagreement as to why. view more (2007-07-24)
Gene expression pattern could lead to improved treatment of pediatric septic shock
A consortium of researchers headed by Cincinnati Children's Hospital Medical Center has discovered a gene expression pattern that could lead to improved diagnosis and treatment of pediatric septic shock - still a serious public health problem despite today's potent antibiotics and pediatric intensive care units. view more (2007-07-27)
The evolution of gene regulation
Even microbes are governed by the principle of supply and demand - at least at the genetic level. Not all of their gene products, the blueprints for proteins, are required at all times. view more (2009-05-26)
Computation to unravel how genes are regulated and shed light on how cells become different
A closer alliance between computational and experimental researchers is needed to make progress towards one of biology's most challenging goals, understanding how epigenetic marks contribute to regulation of gene expression. view more (2008-04-11)
Researchers discover important tool in understanding differentiation in human embryonic stem cells
Researchers at the University of Minnesota's Stem Cell Institute have described how an existing genetic tool can be used to study how human embryonic stem cells differentiate. The research appears in the November 2007 issue of Experimental Biology and Medicine. view more (2007-10-25)
Businesses avoid regulation by stifling growth
Nearly a quarter of businesses questioned by an internet survey revealed they had purposely avoided growing their businesses to avoid the impact of regulation. view more (2005-02-16)
UK government should act now to regulate tobacco
Cigarettes are the deadliest form of nicotine delivery available on the market, yet are the least regulated. An editorial in this week's BMJ argues that the British government should act now to level the regulatory playing field for tobacco and nicotine. It is no coincidence that cigarettes have so far managed to escape regulation, writes... view more... (2003-01-16)
Scientists discover role for dueling RNAs
Researchers have found that a class of RNA molecules, previously thought to have no function, may in fact protect sex cells from self-destructing. view more (2006-11-17)
A brainy idea 25 years in the making
A discovery made 25 years ago about how the brain controls blood pressure regulation is only now being explored with the help of scientists from the Howard Florey Institute. view more (2007-10-04)
DREAM: 1 gene regulates pain, learning and memory
In 2002, a group of scientists at the University of Toronto was able to identify a gene which they dubbed DREAM (downstream regulatory element antagonistic modulator). view more (2009-01-16)
Feeling sleepy is all in your genes
Genes responsible for our 24 hour body clock influence not only the timing of sleep, but also appear to be central to the actual restorative process of sleep, according to research published in the online open access journal BMC Neuroscience. view more (2007-10-18)
New study expands understanding of the role of RNA editing in gene control
For many years, scientists thought gene activity was relatively straightforward: Genes were transcribed into messenger RNA, which was processed and translated into the proteins of the body. view more (2005-12-27)
Med school discovery could lead to better cancer diagnosis, drugs
A Florida State University College of Medicine research team led by Yanchang Wang has discovered an important new layer of regulation in the cell division cycle, which could lead to a greater understanding of the way cancer begins. view more (2008-11-24)
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