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Conserved gene expression reveals our 'inner fish'
A study of gene expression in chickens, frogs, pufferfish, mice and people has revealed surprising similarities in several key tissues. view more (2009-04-16)
From a lowly yeast, researchers divine a clue to human disease
Working with a common form of brewer's yeast, University of Wisconsin-Madison researchers have uncovered novel functions of a key protein that allow it to act as a master regulatory switch - a control that determines gene activity and that, when malfunctioning in humans, may contribute to serious neurological disorders. view more (2006-12-08)
Biologists develop large gene dataset for rice plant
Scientists have reported development of a large dataset of gene sequences in rice. The information will lead to an increased understanding of how genes work in rice, an essential food for much of the world's population. view more (2007-03-14)
Warm, nurturing parents have well-adjusted adolescents
Although preadolescents and adolescents might think their parents hold no sway over them, a study published in the September/October issue of the journal Child Development finds just the opposite - early parenting style makes a big difference in how a child turns out. view more (2005-09-14)
Mapping dynamic Polycomb group proteins during Drosophila development
The developmental passage from a ball of cells to a fruit-fly is a very complicated process involving both temporal and spatial regulation of genes and pathways. view more (2006-04-20)
Microtubule protein interactions visualized en masse
In a new study published online in the open access journal PLoS Biology, Philipp Niethammer, Eric Karsenti, and colleagues investigate the regulation of microtubule dynamics via application of their new method, called visual immunoprecipitation (VIP), which enables simultaneous visualization of multiple protein interactions in cell extracts. view more (2007-01-16)
The regulation of negative emotions: Impact on brain activity
Emotions play an important role in the lives of humans, and influence our behavior, thoughts, decisions, and interactions. The ability to regulate emotions is essential to both mental and physical well-being. view more (2008-03-19)
Chemical Industry Encouraged by Budget Call for Better Regulation
The Chemical Industries Association (CIA) is delighted by today's strong and clear Budget focus on better regulation, and the pioneering approach adopted by Sir Philip Hampton's Report, to which the CIA and its members made a strong contribution. view more (2005-03-16)
Obesity genes revealed
A study of 228 women has revealed genetic variants responsible for body shape. Based on work in the fruit fly Drosophila melanogaster, research published today in the open access journal BMC Genetics identifies natural variation in the human LAMA5 gene as a key determinant of weight. view more (2008-08-11)
Biologists develop genome-wide map of miRNA-mRNA interactions
Researchers at New York University's Center for Comparative Functional Genomics and the University of California, Berkeley have used computational analyses to predict a genome-wide map of microRNA (miRNA) targets in the animal model organism, Caenorhabditis elegans (C. elegans). view more (2006-03-09)
Research elucidates mechanism by which gene expression may be altered in drug addiction
Dr. Judith A. Potashkin, Ph.D. and her colleagues at Rosalind Franklin University of Medicine and Science recently completed a study investigating one of the changes in gene expression that occurs when individuals take addictive drugs. view more (2007-09-05)
Elastic interactions of membrane proteins
Cellular survival relies crucially on the ability to receive and communicate signals from and to the outside world. A major part of this regulation and communication is performed by proteins within the membrane of a cell. view more (2007-05-04)
Genetic on-off switches pinpointed in human genome
In another step to decipher information in the human genome, scientists have discovered the location and sequence of over 10,000 DNA regions that function as genetic on-off switches, or "promoters" in human fibroblasts. view more (2005-07-01)
Listen to your heart: Researchers discover a physiological indicator of vulnerability to temptation
We've all had our moments of weakness when trying to control ourselves; eating that donut on your diet, losing your temper with your kids, becoming upset when you're doing your best not to. It isn't like we plan on these lapses in judgment. It's more like they just sort of happen. view more (2007-03-22)
"Sloppy Genes" Behave Like Their Neighbours: New Findings Reveal That The Regulation Of Gene Expression Is Much Less Strictly Controlled Than Was Previously Thought
The inaugural issue of Journal of Biology features groundbreaking research that challenges the traditional view of how genes are controlled. Our current understanding of gene expression, the fundamental process by which proteins are made from the instructions encoded in DNA, is that the process is tightly controlled so that the correct amount of... view more... (2002-06-13)
UK Chemical Manufacturers Airs its Views at European Public Hearing
Judith Hackitt, Director General of the Chemical Industries Association (CIA), spoke at a European Parliament Public Hearing on REACH (Registration, Evaluation and Authorisation of Chemicals) in Brussels today. view more (2005-01-19)
Conaway Lab Identifies Novel Mechanism for Regulation of Gene Expression
The Stowers Institute's Conaway Lab has demonstrated that an enzyme called Uch37 is kept in check when it is part of a human chromatin remodeling complex, INO80. The results were published in today's issue of Molecular Cell. view more (2008-09-29)
Shilatifard Lab Identifies New Role for Factor Critical to Transcription
The Stowers Institute's Shilatifard Lab has identified a new role for the elongation factor ELL in gene transcription by RNA polymerase II (Pol II) - the enzyme that synthesizes messenger RNA to carry genetic information from DNA to the protein-synthesizing machinery of the cell. view more (2008-06-18)
Autoantibodies common in anorexia patients
A large proportion of anorexia and/or bulimia patients have antibodies against the body's own substances that are involved in the brain's control of eating behavior. The results indicate that there is a connection between eating disturbances and both the nervous system and the immune system. The study was based on 57 women, between the ages of 17... view more... (2002-12-12)
Baumann lab identifies elusive telomere RNA subunit in single cell model
The Stowers Institute's Baumann Lab has identified the long-sought telomerase RNA gene in a single-cell research model. Their findings have been posted to the Web site of the journal Nature Structural & Molecular Biology and will appear in a future print edition. view more (2007-12-28)
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