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Scientists discover the double life of proteins
Scientists at The Australian National University are a step closer to understanding the rare Hartnup disorder after discovering a surprising link between blood pressure regulation and nutrition that could also help to shed light on intestinal and kidney function. view more (2008-04-30)
New gene regulation mechanism discovered
Researchers at Cold Spring Harbor Laboratory have discovered a new kind of messenger RNA molecule that is converted from non-protein coding status to protein coding status in response to cellular stress such as viral infection. view more (2005-10-21)
Plants in the fourth dimension
As anyone who has suffered from jetlag knows, we have internal clocks that tell us when to sleep and wake, and we can be miserable when these are disrupted. view more (2008-07-01)
Cracking the genetic code for control of gene expression
Molecular biologists, developmental biologists and computer scientists at the Universtity of Helsinki, Finland, came together to advance towards cracking the code for how gene expression is controlled. view more (2006-01-13)
Disrupted genetic regulation causes common disturbance in metabolism of fat
The disease familial combined hyperlipidemia (FCH) is a common cause of disturbed metabolism of fat and early heart attacks. Uppsala University scientists have now developed a pioneering method and can show for the first time what genes are regulated by the gene USF1, which is known to cause the disease. view more (2008-02-06)
New genes implicated in high blood pressure
Researchers at the Johns Hopkins University School of Medicine, along with an international team of collaborators, have identified common genetic changes associated with blood pressure and hypertension. view more (2009-05-11)
The Genetics of Fear: Study Suggests Specific Genetic Variations Contribute to Anxiety Disorders
Polymorphisms are variations in genes which can result in changes in the way a particular gene functions and thus may be associated with susceptibility to common diseases. view more (2009-03-11)
Lack of happiness hormone serotonin in the brain causes impaired maternal behavior in mice
A lack of serotonin, commonly known as the "happiness hormone", in the brain slows the growth of mice after birth and is responsible for impaired maternal behavior later in life. view more (2009-06-24)
Genetic marker linked to problem behaviors in adults with developmental disabilities
A common variation of the gene involved in regulating serotonin and norepinephrine in the brain may be linked to problem behaviors in adults with developmental and intellectual disabilities, new research indicates. view more (2009-07-22)
Molecular partners required for appropriate neuronal gene repression
In their efforts to understand the complex biology of life, scientists often seek to isolate individual elements of the puzzle for study, to break the problem down to a more manageable size. Single genes and molecules are closely analyzed to better understand their specific interactions with other single entities within larger systems. view more (2005-08-04)
Comprehensive genetic study paves way for new blood-pressure medicines
Eight previously unknown genes that affect blood pressure were recently identified in a comprehensive international study comprising 34,433 Europeans. view more (2009-05-11)
New study shows that therapeutic gene expression can be sustainable for 1 year
Researchers at the Board of Governors Gene Therapeutics Research Institute at Cedars-Sinai Medical Center have shown for the first time that it is possible to sustain therapeutic gene expression in the central nervous system for up to a year, even in the presence of an anti-viral immune response mechanism that is normally present in humans. view more (2007-10-26)
Role for CISD2 gene in human disease and lifespan control
In the May 15th issue of G&D, Dr. Ting-Fen Tsai (The National Yang-Ming University, Taiwan) and colleagues present a new animal model of human Wolfram Syndrome, and effectively link CISD2 gene function, mitochondrial integrity and aging in mammals. view more (2009-05-15)
International study identifies potential treatment targets for hypertension
Scientists from Massachusetts General Hospital (MGH), as part of a major international research collaboration, have associated common variants in eight regions of DNA with blood pressure levels in human patients. view more (2009-05-11)
Looping genes may hold a key to understanding breast cancer
Another piece of the puzzle that is breast cancer has been found by University of Queensland researchers. view more (2008-04-09)
Genetic pathway responsible for link between body clock disturbance and worsening arthritis
The genes that regulate human circadian rhythm, or 'the body clock', are significantly disturbed in individuals with arthritis. view more (2009-06-11)
A search for biomarkers for early detection of colorectal cancer
Researchers at the Zhejiang University, Hangzhou have discovered that mimecan and Thioredoxin Domain-Containing Protein 5 (TXNDC5) were differentially expressed in colorectal adenoma. view more (2007-09-25)
Delving deeper into the machinery of cocaine addiction
Researchers are now understanding in greater detail the molecular machinery underlying the short-term brain changes that produce the high of cocaine, as well as the longer-term changes behind addiction. Their findings offer hope for targeted drugs that can short-circuit that addiction machinery. view more (2005-10-20)
Cancer researchers found a new mechanism potentially explaining evolution of signalling pathways
Cancer researchers at the University of Helsinki, in trying to find a novel tumor suppressor gene, instead found an important evolutionary change that occurred in a key developmental signalling pathway. view more (2006-02-08)
Iron - the bad guy in haemophilic chronic joint disease?
Mutations in the HFE gene, which is involved in iron regulation, seem to be directly associated with chronic joint disease (or haemophilic arthropathy) among haemophilic patients, claim a team of Portuguese scientists in the April issue of the journal Blood. The results, from a small group of hemophilic patients, if confirmed in a larger... view more... (2005-04-04)
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