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Scientists reveal structure of gateways to gene control
Scientists at Penn State University will reveal in the 29 March 2007 issue of the journal Nature the first complete high-resolution map of important structures that control how genes are packaged and regulated throughout an entire genome. view more (2007-03-29)
Common variation in gene linked to structural changes in the brain
An international group of researchers is the first to show that common variations in a gene - previously shown to be associated with Retts Syndrome, autism, and mental retardation - are associated with differences in brain structure in both healthy individuals and patients with neurological and psychiatric disorders. view more (2009-08-18)
UCLA researchers unravel a mystery about DNA
UCLA researchers in collaboration with researchers at Rutgers University have solved longstanding mysteries surrounding DNA transcription, the first step in carrying out instructions contained in our genes. view more (2006-11-17)
Eating and body weight regulated by specific neurons
Researchers at Yale School of Medicine provide direct evidence that two parts of a neuronal system, one that promotes eating and another that suppresses eating, are critical for the acute regulation of eating and body weight. view more (2005-09-14)
Caltech scientists find cells coordinate gene activity with FM bursts
How a cell achieves the coordinated control of a number of genes at the same time, a process that's necessary for it to regulate its own behavior and development, has long puzzled scientists. view more (2008-10-01)
MicroRNA helps prevent tumors
A microRNA directly regulates a gene implicated in human cancers, researchers from Whitehead Institute and Massachusetts Institute of Technology report in the February 22nd online issue of Science. view more (2007-02-23)
A brave new "old world" of RNA
A new function for RNA, which further elucidates how genes are expressed and regulated, is described on the 25th of November issue of the journal Nature. view more (2004-11-22)
Farnesoid X receptor regulates cystathionase
The expression and activity of Cystathionase is reduced in rodent models of liver injury, leading to hyper-homocysteinemia and impaired generation of hydrogen sulphide, two factors that contribute to endothelial dysfunction and increased intrahepatic resistance. view more (2009-05-13)
UT Southwestern researchers identify new targets for RNAs that regulate genes
Tiny strands of genetic material called RNA - a chemical cousin of DNA - are emerging as major players in gene regulation, the process inside cells that drives all biology and that scientists seek to control in order to fight disease. view more (2008-07-07)
Caltech researchers help unlock the secrets of gene regulatory networks
A quartet of studies by researchers at the California Institute of Technology (Caltech) highlight a special feature on gene regulatory networks recently published in the Proceedings of the National Academy of Sciences (PNAS). view more (2009-02-04)
Glue inside the cell: Ubiquitin builds up an immune response
Ubiquitin is a small protein, which can be attached to other cellular proteins, a process known as ubiquitination. Discoveries in the 1980 th on a key function of ubiquitination in the regulation of protein degradation where awarded with the Nobel Prize for chemistry in 2004. view more (2007-10-22)
Gene expression in labor; and more — press release from PLoS Medicine
A Research Article, Perspective and e-Letter all published today discuss the use of microarrays to discover genes involved in childbirth. The three papers highlight the complexity of such gene expression analyses but also how crucial it is to make original data available for reanalysis. view more (2006-06-13)
New study shows way to avoid overtreatment in breast cancer
The numbers of women who receive adjuvant chemotherapy for breast cancer could be reduced by 30 to 40% if the results of a new molecular study are put into practice. Dr Laura van 't Veer from the Netherlands Cancer Institute told the news briefing that micro array technology* can help predict which breast cancers will metastasise (spread) and... view more... (2002-03-20)
Scientists find gene that modifies severity of cystic fibrosis lung disease
Researchers at Wake Forest University Baptist Medical Center, and colleagues, have identified a gene that modifies the severity of lung disease in people with cystic fibrosis, a lethal genetic condition. The findings open the door to possible new targets for treatment, researchers say. view more (2009-03-04)
Scientists identify a candidate gene for osteoporosis
Today, researchers report the identification of a gene that may play a role in susceptibility to osteoporosis—the crippling disease that leads to bone fractures, especially of the hip and spine. view more (2007-03-29)
Iowa State researcher studies gene families to explore diversity and evolution
Theoretical biologist Stephen Proulx studies gene families to explore how genomes become diverse and evolve. view more (2006-08-01)
Salt of the Earth
A yeast gene responsible for salt tolerance has successfully been used to grow tobacco in a salty environment lethal to most plants. Dr Janey Henderson and Professor Phil Harris from Coventry University inserted the halotolerance gene HAL1 from yeast into a tobacco plant. HAL1 has previously been shown to confer salt tolerance in transgenic tomato... view more... (2001-04-04)
How RNA polymerase II gets the go-ahead for gene transcription
All cells perform certain basic functions. Each must selectively transcribe parts of the DNA that makes up its genome into RNAs that specify the structure of proteins. view more (2009-10-12)
Genetic key to growth of new arteries is identified
Researchers at the San Francisco VA Medical Center have uncovered part of the genetic mechanism that causes new arteries to grow in response to blocked arteries. view more (2005-12-01)
Model unravels rules that govern how genes are switched on and off
For years, scientists have struggled to decipher the genetic instruction book that details where and when the 20,000 genes in a human cell will be turned on or off. Different genes operate in each cell type at different times, and this careful orchestration is what ultimately distinguishes a brain cell from a liver or skin cell. view more (2008-12-05)
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