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Study shows how daughter is different from mother
The mother-daughter relationship can be difficult to understand. Why are the two so different? Now a Northwestern University study shows how this happens. In yeast cells, that is.   view more (2008-08-19)

Foundation trusts threaten core NHS principles
The creation of foundation trusts by the UK government endanger one of the founding principles of the NHS - to provide equal care for equal need, argue doctors in this week's BMJ. The new Health and Social Care Bill abolishes government control of NHS trusts by turning them into foundation trusts - competing independent corporations with powers to... view more... (2003-10-22)

UC Davis researchers discover a key to aggressive breast cancer
In trying to find out why HER2-positive breast cancer can be more aggressive than other forms of the disease, UC Davis Cancer Center researchers have surprisingly discovered that HER2 itself is the culprit. By shutting down its own regulator gene, HER2 creates a permissive environment for tumor growth.   view more (2008-10-31)

MIT researchers unravel bacteria communication pathways
MIT researchers have figured out how bacteria ensure that they respond correctly to hundreds of incoming signals from their environment.   view more (2008-06-13)

A genetic factor predicts prognosis in brain tumor patients
PLoS ONE has just published a study which defines a gene locus on chromosome 1 that predicts prognosis of brain tumor patients and may even set the basis for the development of more efficient drugs to combat brain cancer.   view more (2007-06-28)

'Master regulator' of skin formation discovered
Researchers at Oregon State University have found one gene in the human body that appears to be a master regulator for skin development, in research that could help address everything from skin diseases such as eczema or psoriasis to the wrinkling of skin as people age.   view more (2009-03-25)

Researchers link master regulator of innate immunity to the hypoxic response
Survival of all animals depends on their ability to withstand microbial infections and adapt to fluctuations in oxygen concentrations.   view more (2008-04-24)

Gene controlling circadian rhythms linked to drug addiction, UT Southwestern researchers find
The gene that regulates the body's main biological clocks also may play a pivotal role in drug addiction, researchers at UT Southwestern Medical Center have found.   view more (2005-06-14)

Master regulatory gene of epithelial stem cells identified
The skin's ability to replace the tissue it sloughs off is controlled by a variety of genes. A new study from Harvard Medical School published in the May 4 issue of Cell, however, identifies a "master regulator" of this regeneration process not only for skin, but for many epithelial tissues including breast, prostate, and urogenital... view more... (2007-05-04)

Study identifies 5 genetic themes key to keeping stem cells in a primitive, flexible state
For more than 25 years, stem cells have been defined based on what they can become: more of themselves, as well as multiple different specialized cell types.   view more (2007-06-20)

Cancer researchers found a new mechanism potentially explaining evolution of signalling pathways
Cancer researchers at the University of Helsinki, in trying to find a novel tumor suppressor gene, instead found an important evolutionary change that occurred in a key developmental signalling pathway.   view more (2006-02-08)

Novel connection found between biological clock and cancer
Dartmouth Medical School geneticists have discovered that DNA damage resets the cellular circadian clock, suggesting links among circadian timing, the cycle of cell division, and the propensity for cancer.   view more (2006-06-30)

New breakthrough in global warming plant production
Researchers at the universities of Leicester and Oxford have made a discovery about plant growth which could potentially have an enormous impact on crop production as global warming increases.   view more (2009-03-31)

Genetic variation linked to age-related macular degeneration
The combination of a certain genetic variation, along with inflammatory factors and smoking, significantly increases the risk of the vision disorder age-related macular degeneration   view more (2006-07-19)

Heart regenerates after infarction -- first trials with mice
Up until today scientists assumed that the adult heart is unable to regenerate. Now, researchers and cardiologists from the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch and the Charité - Universitätsmedizin Berlin (Germany) have been able to show that this dogma no longer holds true.   view more (2008-12-12)

New diagnostic advance seen for head, throat cancer
Pharmacy researchers at Oregon State University today announced the discovery of a genetic regulator that is expressed at higher levels in the most aggressive types of head and neck cancers, in work that may help to identify them earlier or even offer a new therapy at some point in the future.   view more (2009-04-29)

Clues to gene expression in cystic fibrosis will guide research
Genetics tests could help provide cystic fibrosis (CF) patients with targeted treatment in future, pilot study authors suggest. Results from a French clinical trial published today in BMC Medicine show how a small percentage of CF sufferers with a rare genetic stop mutation responded positively to gentamicin treatment.   view more (2007-03-29)

Protein amplification in melanoma is possible drug target
Researchers have pinpointed specific gene and protein over-production in metastatic melanoma, pointing the way to a possible new drug target, according to a study published in Nature July 7.   view more (2005-07-11)

Protein-protein interaction explains vision loss in genetic diseases
The mystery of genetic disease is only partially solved with the identification of a mutated gene. Often, the pattern of disease - the features or disorders associated with it - vary in type and severity among those who are affected. Scientists, physicians and patients all ask why.   view more (2009-05-11)

'Gateway' gene discovered for brain cancer
Researchers have discovered that the same genetic regulator that triggers growth of stem cells during brain development also plays a central role in the development of the lethal brain cancer malignant glioma.   view more (2007-02-15)
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