Gene Silencing Current Events | Gene Silencing News | 10
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Gene variant linked to risk of stroke and heart attack for those on Plavix A new study reports that a gene variant carried by about a third of the population plays a major role in this group's response to an anti-clotting medicine, clopidogrel (Plavix). People with the variant produce a defective version of the CYP2C19 enzyme and are less able to activate the drug. view more (2009-08-26)
Gene for neat repair of DNA discovered Researchers from the Erasmus University in Rotterdam have demonstrated that a gene helps in the neat repair of DNA. Without this gene the body would repair damaged DNA in a careless manner more often. This causes new damage, which can lead to cancer. The careless repair of damaged DNA can cause mutations and can result in cancer. Cell biologists... view more... (2002-01-24)
Jefferson scientists uncover gene mutation that cuts colon polyps, may suppress cancer Cancer biologists at the Kimmel Cancer Center at Jefferson have found a gene mutation that can dramatically reduce the number of colon polyps that develop, and in turn, potentially cut the risk of cancer. view more (2007-03-22)
Gene Variation Can Lower Susceptibility To HIV Infection Researchers at The University of Manchester have identified small variations in a gene which can determine whether a person contracts HIV or develops AIDS. Professor Bill Ollier, and Dr Ali Hajeer, of the ARC Epidemiology Unit at The University of Manchester, have found new variants of the RANTES gene that seem to play a role in rendering people... view more... (2000-11-21)
Conserved gene expression reveals our 'inner fish' A study of gene expression in chickens, frogs, pufferfish, mice and people has revealed surprising similarities in several key tissues. view more (2009-04-16)
Gene variations linked to brain aneurysms Variations in a gene seem to be linked to brain (cerebral) aneurysms, suggests research published ahead of print in the Journal of Neurology Neurosurgery and Psychiatry. view more (2006-04-27)
Biologists develop large gene dataset for rice plant Scientists have reported development of a large dataset of gene sequences in rice. The information will lead to an increased understanding of how genes work in rice, an essential food for much of the world's population. view more (2007-03-14)
Early predictor of breast cancer aggressiveness Physicians may be able to make early decisions on the best treatment for breast cancer, thanks to research published in Breast Cancer Research today. A gene involved in the adhesion of cells is less active in breast tumors with a poor prognosis than those that are less aggressive, researchers found. Measuring the activity of the ALCAM gene in... view more... (2004-06-24)
Genetic sleuth solves glaucoma mystery Dr. Michael Walter is one good gumshoe. The University of Alberta medical geneticist has cracked the case of WDR36, a gene linked to glaucoma. view more (2009-03-20)
Standing up to paraplegia with gene therapy Elena Rugarli and colleagues from the National Neurological Institute in Milan have used gene therapy to save sensory and skeletal muscle nerve fibers from degeneration in mice with hereditary spastic paraplegia (HSP). view more (2005-12-16)
Ob1, the first commmon obesity gene was located on chromosome 10 Each family has at least one member whose body mass index (BMI, the ratio of the weight in kg to the surface of the body in m2; normal BMI is below 25) is higher than 40 and at least one other member whose BMI is over 27. 380 genetic markers, covering 23 pairs of chromosomes, were studied in order to find genetic similarities between the obese... view more... (1998-11-16)
The future of personalized cancer treatment: An entirely new direction for RNAi delivery In technology that promises to one day allow drug delivery to be tailored to an individual patient and a particular cancer tumor, researchers at the University of California, San Diego School of Medicine, have developed an efficient system for delivering siRNA into primary cells. view more (2009-05-18)
A potential route for human tumor gene therapy The type 1 Na+/H+ exchanger (NHE1) is a transmembrane protein found in all eukaryotic cells. One of its functions is to evacuate excessive H+ in the cytoplasm by means of Na+-H+ exchange, resulting in stable intracellular pH value. view more (2008-05-21)
Postmortem data support link between gene and schizophrenia We have known for a long time that there is a genetic component to schizophrenia, but nailing down the gene(s) has not been easy. view more (2005-09-13)
Technique finds gene regulatory sites without knowledge of regulators A new statistical technique developed by researchers at the University of Illinois allows scientists to scan a genome for specific gene-regulatory regions without requiring prior knowledge of the relevant transcription factors. view more (2009-11-20)
Scientists identify a gene that may suppress colorectal cancer In today's online edition of Genome Research, a husband-and-wife research team from Thomas Jefferson University report the discovery of a gene that, when mutated, may suppress colorectal cancer. view more (2007-03-22)
Scientists identify gene that may contribute to improved rice yield A team of scientists, including Penn State Distinguished Professor of Biology Hong Ma, has identified a gene in rice that controls the size and weight of rice grains. view more (2008-09-29)
Gene therapy shows promise as weapon against HIV A new UCLA AIDS Institute study has found that gene therapy can be developed as a safe and active technique to combat HIV. view more (2009-02-23)
Growth gene linked to cancer Growth gene linked to cancer view more (1999-12-16)
Location Of Gene For Ear Wax Could Increase Understanding Of Apocrine-Gland Development (p 2000) Japanese authors of a research letter in this week's issue of THE LANCET describe how a chance discovery of the location for the gene which codes for ear wax could be a useful step towards a better understanding of the apocrine glands. There are two forms of human ear wax, wet and dry, determined by one specific gene. Wet ear wax is common in... view more... (2002-06-05)
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