Gene Silencing Current Events | Gene Silencing News | 11
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Penn researchers discover 'modus operandi' of heart muscle protein
Researchers at the University of Pennsylvania School of Medicine have discovered that a protein called leiomodin (Lmod) promotes the assembly of an important heart muscle protein called actin. What's more, Lmod directs the assembly of actin to form the pumping unit of the heart. The findings appear in this week's issue of Science. view more (2008-04-11)
GENETIC SUSCEPTIBILITY TO INFERTILITY (p 1336)
In women, unsuccessful attachment and implantation of fertilised eggs (embryos) to the lining of the womb (endometrium), resulting in infertility, could be influenced by variation of a specific gene, conclude authors in a preliminary study described in a research letter in this week's issue of the Lancet. The failure of embryo implantation is... view more... (2001-04-25)
Breathe deep: Which patients could benefit from inhaled steroids in cystic fibrosis?
A specific variation in the glucocorticoid receptor gene is associated with lung disease progression in cystic fibrosis, research published this week in the online open access journal Respiratory Research reveals. view more (2007-11-29)
Gene therapy accelerates healing of damaged skeletal muscle
University of Pittsburgh School of Medicine researchers have successfully used gene therapy to accelerate muscle regeneration in experimental animals with muscle damage, suggesting this technique may be a novel and effective approach for improving skeletal muscle healing, particularly for serious sports-related injuries. view more (2006-06-05)
Nature press release on DiGeorge syndrome paper
[410097] LIFELINES: CATCH 22 (pp97–101) In the 1 March issue of Nature, researchers from Baylor College of Medicine in Texas pinpoint the gene behind one of the most common genetic diseases to affect humans: DiGeorge syndrome. The disease results in a broad spectrum of symptoms, including heart abnormalities, disruption of the immune system... view more... (2001-02-23)
New link between estrogen and breast cancer
The female sex hormone estrogen turns on a gene linked to breast cancer, according to new research by Brisbane scientists. view more (2007-08-27)
Trojan horse for ovarian cancer -- nanoparticles turn immune system soldiers against tumor cells
In a feat of trickery, Dartmouth Medical School immunologists have devised a Trojan horse to help overcome ovarian cancer, unleashing a surprise killer in the surroundings of a hard-to-treat tumor. view more (2009-07-16)
A new take on growth factor signaling in tamoxifen resistance
Differences in growth factor (GF) signaling may cause the poor prognosis in some breast cancer cases. A new study, published in the open access journal BMC Medical Genomics, suggests that some estrogen receptor-positive breast cancers respond poorly to tamoxifen because of increased GF signaling. view more (2009-06-24)
MSU research: Genes may influence popularity
A groundbreaking study of popularity by a Michigan State University scientist has found that genes elicit not only specific behaviors but also the social consequences of those behaviors. view more (2008-12-22)
Evolution is driven by gene regulation
It is not just what's in your genes, it's how you turn them on that accounts for the difference between species - at least in yeast - according to a report by Yale researchers in this week's issue of Science. view more (2007-08-10)
Food cue-related brain activity linked to obesity?
A unique pattern of gene expression observed in rats may be linked to a conditioned desire for food and excessive food intake, an article published today in BMC Biology suggests. view more (2007-04-27)
Historic gene therapy trial to treat Alzheimer's disease underway at Georgetown
Researchers in the Memory Disorders Program at Georgetown University Medical Center are now recruiting volunteers for a national gene therapy trial - the first study of its kind for the treatment of patients with dementia due to Alzheimer's disease. view more (2009-09-23)
Scientists identify gene that influences alcohol consumption
A variant of a gene involved in communication among brain cells has a direct influence on alcohol consumption in mice, according to a new study by scientists supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health (NIH), and the U.S. Army. view more (2007-12-06)
Researchers within sight of a breakthrough on blindness
The discovery by a Leeds University scientist of a new blindness gene could help to save the sight of thousands of sufferers of retinal disease which affects premature babies as well as people over 60. view more (2004-11-03)
Brown Scientists Explain Inception of Perception in the Brain
The taste of champagne, the sound of a train, the flash of a pop fly into left field - indeed all of human perception - begins in the brain's center. That's where sensory information passes from the thalamus to the neocortex for processing. view more (2007-03-06)
New hereditary gene linked to Parkinson's disease
UCL scientists have discovered a new gene implicated in the early development of Parkinson's disease. In a study of families with early onset disease, Professor Nick Wood and colleagues at UCL's Institute of Neurology identified a novel gene which produces a malfunctioning protein that could pave the way for new treatments for Parkinson sufferers.... view more... (2004-04-15)
Analysis of breast-cancer gene role offers promising target
Researchers at UT Southwestern Medical Center have for the first time described how multiple copies of a gene are responsible for metastases in early-stage breast cancer and poor prognosis for patients. view more (2006-10-31)
Survival of the fittest: even cancer cells follow the laws of evolution
Scientists from The Institute of Advanced Studies at Princeton and the University of California discovered that the underlying process in tumor formation is the same as for life itself-evolution. view more (2008-08-04)
Researchers identify gene associated with muscular dystrophy-related vision problems
Skeletal muscle disease and vision deficits might seem unrelated, but a frog model of muscular dystrophy shows it is not such a leap. view more (2009-04-21)
Faulty gene linked to prostate cancer risk
Missing sections of a gene, which programmes the manufacture of a chemical to alert the body to DNA damage. view more (2006-10-31)
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