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New Genetic Mechanism For Evolution
A team of researchers from the Universitat Autònoma de Barcelona (UAB) has discovered that transposons, small DNA sequences that travel through the genomes, can silence the genes adjacent to them by inducing a molecule called antisense RNA. This is a new mechanism for evolution that has been unknown until now. The research has been recently... view more... (2004-07-16)
How embryonic stem cells develop into tissue-specific cells demonstrated
While it has long been known that embryonic stem cells have the ability to develop into any kind of tissue-specific cells, the exact mechanism as to how this occurs has heretofore not been demonstrated. view more (2008-05-13)
Cancer cells suppress large regions of DNA by a reversible process that can be tackled
Cancer researchers at Sydney's Garvan Institute, in collaboration with Spanish scientists, have formulated a new concept for how cancer cells can escape normal growth controls, which may have far-reaching implications for the new generation of cancer therapies. view more (2006-04-24)
Plant polymerases IV and V are special forms of Polymerase II
It's a little like finding out that Superman is actually Clark Kent. A team of biologists at Washington University in St. Louis has discovered that two vital cellular components, nuclear RNA Polymerases IV and V (Pol IV and V), found only in plants, are actually specialized forms of RNA Polymerase II, an essential enzyme of all eukaryotic... view more... (2009-01-07)
Vitamin extends life in yeast, Dartmouth Medical School researchers find
Imagine taking a vitamin for longevity! Not yet, but a Dartmouth discovery that a cousin of niacin prolongs lifespan in yeast brings the tantalizing possibility a step closer. view more (2007-05-04)
Class of antibiotics can enhance gene-silencing tool
A way to turn off one gene at a time has earned acceptance in biology laboratories over the last decade. Doctors envision the technique, called RNA interference, as a tool to treat a variety of diseases if it can be adapted to humans. view more (2008-07-21)
Scientists find clue to mechanisms of gene signaling and regulation
Scientists have discovered a pattern in the DNA sequence of the mouse genome that may play a fundamental part in the way DNA molecules regulate gene expression. view more (2007-08-23)
Researchers may have unlocked the mechanisms that silence the estrogen receptor gene alpha during breast cancer
The mechanisms that silence the estrogen receptor gene alpha (ER-α) in certain breast cancer cell lines may be closer to being unlocked. view more (2007-08-20)
Novel enzyme offers new look at male hormone regulation
For the second time in less than a year, University of North Carolina at Chapel Hill scientists have purified a novel protein and have shown it can alter gene activity by reversing a molecular modification previously thought permanent. view more (2006-05-08)
Gene therapy 'turns off' mutation linked to Parkinson's disease
A group of Northwestern University researchers is developing a novel gene therapy aimed at selectively turning off one of the genes involved in the development of Parkinson's disease. view more (2006-01-19)
Twin molecular scissors link creation of microRNAs with gene-silencing
One of the body's primary strategies for regulating its genome is a kind of targeted gene silencing orchestrated by small molecules called microRNAs, or miRNAs. view more (2005-11-04)
UK physician revolutionizes gene research
A dramatic new study published in the most recent issue of Nature questions some of the mechanisms underlying a new class of drugs based on Nobel Prize-winning work designed to fight diseases ranging from macular degeneration to diabetes. view more (2008-03-27)
Mapping dynamic Polycomb group proteins during Drosophila development
The developmental passage from a ball of cells to a fruit-fly is a very complicated process involving both temporal and spatial regulation of genes and pathways. view more (2006-04-20)
RNA interference therapy heals growth deficiency disorder in a live animal
A team of Vanderbilt researchers have demonstrated for the first time that a new type of gene therapy, called RNA interference, can heal a genetic disorder in a live animal. view more (2007-12-19)
Linchpin gene may be useful target for new breast cancer therapies
University of Iowa researchers have discovered a gene that plays a linchpin role in the ability of breast cancer cells to respond to estrogen. The finding may lead to improved therapies for hormone-responsive breast cancers and may explain differences in the effectiveness of current treatments. view more (2007-09-17)
Gene packaging tells story of cancer development
To decipher how cancer develops, Johns Hopkins Kimmel Cancer Center investigators say researchers must take a closer look at the packaging. view more (2008-12-05)
Scientists lift malaria's cloak of invisibility
The world's deadliest malaria parasite, Plasmodium falciparum, sneaks past the human immune system with the help of a wardrobe of invisibility cloaks. view more (2005-12-29)
DNA editing tool flips its target
Imagine having to copy an entire book by hand without missing a comma. Our cells face a similar task every time they divide. They must duplicate both their DNA and a subtle pattern of punctuation-like modifications on the DNA known as methylation. view more (2008-09-04)
Researchers solve piece of large-scale gene silencing mystery
A team led by Craig Pikaard, Ph.D., Washington University in St. Louis professor of biology in Arts & Sciences, has made a breakthrough in understanding the phenomenon of nucleolar dominance, the silencing of an entire parental set of ribosomal RNA genes in a hybrid plant or animal. view more (2008-12-05)
UCR-led study identifies crucial mechanism involved in immune response against viruses
A research team led by UC Riverside scientists has shown that the common fruit fly can serve as an excellent model for studying the immunity animals are born with for fighting viral infections. view more (2006-03-24)
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