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Researchers find protein that silences genes
A team of researchers, including biologists at Washington University in St. Louis, has discovered the key role one protein plays in a major turn-off - in this case, the turning off of thousands of nearly identical genes in a hybrid plant.   view more (2006-05-08)

New gene silencing therapy for cervical cancer
Researchers at The University of Queensland's (UQ) Centre for Immunology and Cancer Research (CICR), based at the Princess Alexandra Hospital, have pioneered a new approach for the treatment of cervical cancer.   view more (2005-11-17)

Tool developed to silence genes in specific tissues using RNAi
Researchers at The University of Texas M. D. Anderson Cancer Center say they have jumped a significant hurdle in the use of RNA interference (RNAi), believed by many to be the ultimate tool to both decode the function of individual genes in the human genome and to treat disease.   view more (2006-01-17)

Courtship pattern shaped by emergence of a new gene in fruit flies
When a young gene known as sphinx is inactivated in the common fruit fly, it leads to increased male-male courtship, scientists report in the May 27, 2008, issue of the Proceedings of the National Academy of Sciences.   view more (2008-05-27)

A breakthrough in gastric carcinogenesis
Checkpoint with forkhead and ring finger (CHFR) is a mitotic stress checkpoint gene whose promoter is frequently methylated in various kinds of cancer.   view more (2009-06-12)

Researchers reveal repressor protein blocks neural stem cell development
A protein known to repress gene transcription at the molecular level in a variety of processes also blocks embryonic neural stem cells from differentiating into neurons.   view more (2007-10-11)

Targeting a key enzyme with gene therapy reversed course of Alzheimer's disease in mouse models
In mice, that had been genetically engineered to develop Alzheimer's disease, scientists were able to reverse the rodents' memory loss by reducing the amount of an enzyme that is crucial for the development of Alzheimer's disease.   view more (2005-09-22)

Genome communication
In the late 19th century Gregor Mendel used peas to show that one copy of a gene (allele) is inherited from the mother and one from the father.   view more (2008-06-30)

Stowers Institute's Workman Lab discovers novel histone demethylase protein complex
The Stowers Institute's Workman Lab has discovered a novel histone demethylase protein complex characterized in work published today in Molecular Cell.    view more (2008-12-08)

Helping Tomatoes Cope With Stress May Be Good For Us
Scientists at the John Innes Centre (JIC)(1) and Institute of Food Research (IFR)(2), Norwich, have today reported the discovery and use of a gene that may help protect plants and humans against disease. The gene (HQT) was identified in tomato and is responsible for producing an antioxidant called chlorogenic acid (CGA). By increasing the... view more... (2004-04-26)

RNA molecules, delivery system improve vaccine responses, effectiveness
A novel delivery system that could lead to more efficient and more disease-specific vaccines against infectious diseases has been developed by biomedical engineers at The University of Texas at Austin.   view more (2008-10-09)

Interfering RNA silences genes in 'slippery' immune cells
A technical advance in laboratory techniques may provide biology researchers broader access to RNA interference, a process of blocking the activity of targeted genes.   view more (2006-05-09)

Gene silencing technique offers new strategy for treating, curing disease
A new technique aimed at directly controlling the expression of genes by turning them on or off at the DNA level could lead to drugs for the treatment or cure of many diseases, say researchers at UT Southwestern Medical Center.   view more (2005-08-01)

New therapeutic strategy could target toxic protein in most patients with Huntington's disease
Howard Hughes Medical Institute researchers have designed tiny RNA molecules that shut off the gene that causes Huntington's disease without damaging that gene's healthy counterpart, which maintains the health and vitality of neurons.   view more (2009-04-10)

CSHL scientists discover how 'companion' cells to sperm protect them from genetic damage
In plant pollen grains, sperm cells, which carry the genetic material to be passed on to progeny, are cocooned within larger "companion" cells that are called pollen vegetative cells. These companions provide sperm with energy and nourishment, and push them towards their targets during fertilization.   view more (2009-02-06)

UGA scientists engineer root-knot nematode resistance
University of Georgia professor Richard Hussey has spent 20 years studying a worm-shaped parasite too small to see without a microscope.   view more (2006-09-27)

Study finds 231 new genes associated with head and neck cancer
A Henry Ford Hospital study has identified 231 new genes associated with head and neck cancer, one of the most deadly cancers responsible for 2.1 percent of all cancer deaths in the United States.   view more (2009-10-05)

Identified mechanism in the malaria parasite to help it adapt to infected individuals
Plasmodium falciparum is responsible for the most severe forms of human malaria. Invasion of host red blood cells is an essential step of the complex life cycle of this parasite.   view more (2007-08-03)

Killing the messenger RNA — But which one?
Tiny molecules called microRNAs, only 19 to 21 nucleotides in length, are able to effectively silence sometimes large sets of genes. They do this by specifically binding to and neutralizing another form of RNA called messenger RNA, responsible for conveying the information from genes to the cellular machinery that uses that information to create... view more... (2007-02-23)

'Insulator' helps silence genes in dormant herpes virus
By adulthood, most people have suffered at least one bout of painful cold sores brought on by the Herpes simplex virus 1, also known as HSV-1.   view more (2007-05-03)
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