Gene Silencing Current Events | Gene Silencing News | 4
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Scientists link fragile X tremor/ataxia syndrome to binding protein in RNA
Scientists have discovered a key protein in the toxic brain pathway that leads to fragile X tremor/ataxia syndrome (FXTAS), an inherited neurodegenerative disorder. view more (2007-08-16)
Licorice compound offers new cancer prevention strategy
A chemical component of licorice may offer a new approach to preventing colorectal cancer without the adverse side effects of other preventive therapies, Vanderbilt University Medical Center researchers report. view more (2009-03-24)
atugen AG demonstrates in vivo proof-of-concept in siRNA therapeutics
Berlin, 11 May 2004 - atugen AG, The Gene Silencing Company, announced today that it has demonstrated, in vivo, proof-of-concept in functional delivery of its highly stable siRNA therapeutics. In a series of repeat studies to test glucose tolerance in normal rodents, atugen's siRNA therapy was shown to be effective in regulating blood sugar... view more... (2004-05-11)
Cost-effective method for gene silencing is featured in Cold Spring Harbor Protocols
Nearly a decade ago, now-Nobel laureates Craig Mello and Andrew Fire discovered that they could insert short RNA molecules into worms and shut down specific genes. view more (2007-08-02)
Small RNAs can play critical roles in male infertility/contraception
University of Nevada School of Medicine scientists in the Department of Physiology and Cell Biology have discovered insight into the reproductive workings of the male sex chromosome that may have significant implications for male infertility and contraception. view more (2009-04-10)
200,000 rice mutants available worldwide for scientific investigation
Scientists across the world are building an extensive repository of genetically modified rice plants in the hope of understanding the function of the approximately 57,000 genes that make up the genome of Oryza sativa. view more (2009-03-05)
Neural stem cells derived from human embryonic stem cells carry abnormal gene expression
Neural stem cells grown from one of the federally approved human embryonic stem cell lines proved to be inferior to neural stem cells derived from fetal tissue donated for research, a UCLA study has found. view more (2006-08-07)
Ancient DNA helps UF researchers unearth potential hemophilia therapy
A cut can be life-threatening for people with hemophilia, whose bodies don't produce enough of a protein that prevents prolonged bleeding. view more (2006-02-28)
New study shows that therapeutic gene expression can be sustainable for 1 year
Researchers at the Board of Governors Gene Therapeutics Research Institute at Cedars-Sinai Medical Center have shown for the first time that it is possible to sustain therapeutic gene expression in the central nervous system for up to a year, even in the presence of an anti-viral immune response mechanism that is normally present in humans. view more (2007-10-26)
Looping genes may hold a key to understanding breast cancer
Another piece of the puzzle that is breast cancer has been found by University of Queensland researchers. view more (2008-04-09)
Scripps research team reverses Friedreich's ataxia defect in cell culture
In the new study, the researchers tested a variety of compounds that inhibited a class of enzymes known as histone deacetylases in a cell line derived from blood cells from a Fredreich's ataxia sufferer. view more (2006-08-22)
USC study in Nature Genetics supports a stem cell origin of cancer
Researchers at the University of Southern California (USC) recently made significant strides toward settling a decades-old debate centering on the role played by stem cells in cancer development. view more (2007-01-10)
Gene expression in labor; and more — press release from PLoS Medicine
A Research Article, Perspective and e-Letter all published today discuss the use of microarrays to discover genes involved in childbirth. The three papers highlight the complexity of such gene expression analyses but also how crucial it is to make original data available for reanalysis. view more (2006-06-13)
Iowa State researcher studies gene families to explore diversity and evolution
Theoretical biologist Stephen Proulx studies gene families to explore how genomes become diverse and evolve. view more (2006-08-01)
Salt of the Earth
A yeast gene responsible for salt tolerance has successfully been used to grow tobacco in a salty environment lethal to most plants. Dr Janey Henderson and Professor Phil Harris from Coventry University inserted the halotolerance gene HAL1 from yeast into a tobacco plant. HAL1 has previously been shown to confer salt tolerance in transgenic tomato... view more... (2001-04-04)
MicroRNAs grease the cell's circadian clockwork
Most of our cells possess an internal clock, a group of genes displaying a cyclic expression pattern that reaches a peak once a day. view more (2009-06-01)
New gene linked to bipolar disorder
A new gene linked to both depression and bipolar disorder has been identified by UCL (University College London) and Danish researchers. view more (2006-10-04)
A potential targeting gene therapy for developing HCV
Gene therapy has emerged as a novel approach to combat HCV infection in the last few years. view more (2009-07-16)
Fatty spheres loaded with siRNA shrink ovarian cancer tumors in preclinical trial
A molecular "off" switch packaged in a tiny sphere penetrates deeply into ovarian cancer tumor cells, stifling a troublesome protein and drastically reducing the size of tumors. view more (2006-08-15)
First Parkinson's Gene Therapy Patient Passes One Year
The first ever patient to have undergone gene therapy for Parkinson's appears to have come through phase I without a hitch, suggesting that the therapy is safe and effective, reports Marina Murphy in Chemistry & Industry. view more (2004-09-02)
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