Gene Silencing Current Events | Gene Silencing News | 9
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Gene-expression profiling of the effects of liver toxins
Gene-expression data from liver tissue or whole blood can be used to classify histopathologic differences in the effects of hepatotoxins. It is hoped that these findings, published in BioMed Central's open access journal, Genome Biology, will lead to a more precise way of defining the potential hepatotoxicity of new compounds. view more (2008-06-20)
Stoned sea-squirts
The psychoactive ingredient of the drug cannabis exerts its effects on the human brain by activating proteins known as cannabinoid receptors. Dr. Maurice Elphick of Queen Mary, University of London has uncovered the first evidence that cannabinoid receptors may not be unique to humans and other vertebrates. The genome of the sea- squirt was... view more... (2004-03-31)
Yeast mimics severity of mutations leading to fatal childhood illness
Scientists report that human gene mutations expressed in yeast cells can predict the severity of Batten Disease, a fatal nervous system disorder that begins during childhood. view more (2008-12-22)
Gene Test Could Reduce Unnecessary Treatment For Women With Breast Cancer (pp 340, 362)
In this week's issue of THE LANCET, US researchers describe how gene expression profiles could determine whether or not women with breast cancer would respond to docetaxel treatment. Women who are likely to be resistant to the drug could be given alternative treatment. Chemotherapy or hormonal treatment after surgery for breast cancer is crucial... view more... (2003-07-30)
U-M researchers identify gene involved in breast cancer
Researchers at the University of Michigan Comprehensive Cancer Center have identified a gene linked to the development of an aggressive form of breast cancer. view more (2007-07-27)
New strategy rapidly identifies cancer targets
In a step toward personalized medicine, Howard Hughes Medical Institute investigator Brian J. Druker and colleagues have developed a new technique to identify previously unknown genetic mutations that can trigger cancerous growth. view more (2006-07-17)
Unique soybean lines hold promise for producing allergy-free soybeans
Researchers have isolated two Chinese soybean lines that grow without the primary protein linked to soy allergies in children and adults. view more (2006-05-05)
Autism Consortium members publish in PNAS: Mechanism, treatment for Rett syndrome -- top cause autism girls
The Autism Consortium, an innovative research, clinical and family collaboration dedicated to radically accelerating research and enhancing clinical care for autism spectrum disorders (ASDs), announced today that several Consortium members published a paper with significance for clinical trials in autism in the Proceedings of the National Academy... view more... (2009-02-10)
Promising treatment target found in Hodgkin lymphoma
Dana-Farber Cancer Institute scientists have identified a protein that prevents the body's immune system from recognizing and attacking Hodgkin lymphoma cells. view more (2007-07-31)
Three new species of lemurs identified
Researchers have identified three new species of lemurs, the small, big-eyed primates native to the island of Madagascar. view more (2006-02-23)
Scientists Discover Cause Of Leukaemia That Halted Treatment Trial For 'Baby-in-a-Bubble' Syndrome
Medical Research Council (MRC) scientists have helped establish the cause of the leukaemia which developed in two young patients taking part in a pioneering gene therapy trial to treat the fatal 'baby-in-a-bubble' syndrome, severe combined immunodeficiency (X-SCID). The trial at the Necker-Enfants Malades clinic in Paris was stopped last year due... view more... (2003-10-16)
Farmers Could Be Predisposed To Adverse Health Effects Of Sheep Dip (p 763)
A research letter in this week's issue of THE LANCET suggests that some farmers may have a genetic predisposition to the adverse health effects associated with exposure to organophosphates present in sheep dip. Exposure to organophosphates has acute effects on health, but evidence of chronic effects is unclear. An enzyme found in blood... view more... (2002-02-28)
Cancer: Another step towards medication
The gene Myc is an important factor for the growth of organisms by cell division. It causes the production of a protein which, as a transcription factor, controls the expression of up to 15 % of all human genes. view more (2009-03-18)
Nanomedical approach targets multiple cancer genes, shrinks tumors more effectively
Nanoparticles filled with a drug that targets two genes that trigger melanoma could offer a potential cure for this deadly disease, according to cancer researchers. view more (2008-09-16)
Gene signature assesses breast cancer outcomes
A test that looks at the expression of 70 genes linked to breast cancer can accurately assess a patient's risk of recurrence or death. view more (2006-09-06)
Gene linked with mental illness shapes brain region, researchers find
A gene variant associated with mental illness goes hand-in-hand with enlargement of a brain region that handles negative emotions, researchers at UT Southwestern Medical Center and the Central Texas Veterans Health Care System have found. view more (2006-11-08)
Finding the ZIP-code for gene therapy: Scientists imitate viruses to deliver therapeutic genes
A research report featured on the cover of the September 2009 print issue of The FASEB Journal describes how Australian scientists developed a new gene therapy vector that uses the same machinery that viruses use to transport their cargo into our cells. view more (2009-08-31)
Gene therapy effective treatment against gum disease
Scientists at the University of Michigan have shown that gene therapy can be used to successfully stop the development of periodontal disease, the leading cause of tooth loss in adults. view more (2008-12-11)
Cells in mucus from lungs of high-risk patients can predict tumor development
n a group of high-risk patients, a test that examined DNA from cells expelled in sputum for evidence of "silenced" genes correctly identified the majority of patients who were later diagnosed with lung cancer. view more (2006-03-15)
New tool probes function of rice genes
A new tool for investigating the rice genome has been developed by researchers at UC Davis led by Pamela Ronald, professor of plant pathology. view more (2008-10-09)
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