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MRC Research Offers Hope of Treatment for People with Duchenne Muscular Dystrophy
A new approach which effectively patches over genetic defects offers hope of treatment to people with the terminal illness, Duchenne muscular dystrophy. This is the conclusion of research led by Dr Qi Long Lu and Professor Terence Partridge at the Medical Research Council's Clinical Sciences Centre. Most cases of Duchenne muscular dystrophy are... view more... (2003-07-04)
Did the gene for ADHD help our nomadic ancestors?
An ADHD-associated version of the human gene DRD4 is linked to better health among nomadic tribesmen, but may cause malnourishment in their settled cousins, according to new research by a team directed by an anthropologist at the University of Wisconsin-Milwaukee (UWM). view more (2008-06-17)
Common cold virus efficiently delivers corrected gene to cystic fibrosis cells
Scientists have worked for 20 years to perfect gene therapy for the treatment of cystic fibrosis, which causes the body to produce dehydrated, thicker-than-normal mucus that clogs the lungs and leads to life threatening infections. view more (2009-07-21)
Gene therapy slows progression of fatal neurodegenerative disease in children
Gene therapy to replace the faulty CLN2 gene, which causes a neurodegenerative disease that is fatal by age 8-12 years, was able to slow significantly the rate of neurologic decline in treated children. view more (2008-05-14)
Junk DNA may prove invaluable in quest for gene therapies
Scientists have identified how a protein enables sections of so-called junk DNA to be cut and pasted within genetic code - a finding which could speed development of gene therapies. view more (2009-09-22)
Core needle biopsy gives an accurate picture of gene expression in whole tumor
The gene expression profile detected in the core needle biopsy of a breast tumour is representative of gene expression in the whole tumour. view more (2006-08-21)
Does missing gene point to nocturnal existence for early mammals?
A gene that makes cells in the eye receptive to light is missing in humans, researchers have discovered. view more (2006-10-13)
Cranberries can treat herpes
Alpine cranberries have significant biological activity that can help to combat herpes virus type II (HSV-2) infection, one of the most common viral infections in humans, writes Emma Dorey in Chemistry & Industry. view more (2004-10-15)
Researchers develop new, more-sensitive assay for detecting DNA methylation in colon cancer
A study published in this week's online issue of Nature Biotechnology, demonstrates a unique and highly sensitive method for detecting methylation-associated cancers. view more (2009-08-17)
The genetic basis for autoimmunity discovered
Researchers from the Basque University have discovered the relationship between E2F2 gene and autoimmunity. The Science Faculty team, leaded by Ana Zubiaga has published the results of its researches in the fifteenth issue of the Immunity magazine. The team began analysing E2F2 gene and its family. This gene family is responsible for the cell... view more... (2002-03-01)
Gene-expression profiling of the effects of liver toxins
Gene-expression data from liver tissue or whole blood can be used to classify histopathologic differences in the effects of hepatotoxins. It is hoped that these findings, published in BioMed Central's open access journal, Genome Biology, will lead to a more precise way of defining the potential hepatotoxicity of new compounds. view more (2008-06-20)
Stoned sea-squirts
The psychoactive ingredient of the drug cannabis exerts its effects on the human brain by activating proteins known as cannabinoid receptors. Dr. Maurice Elphick of Queen Mary, University of London has uncovered the first evidence that cannabinoid receptors may not be unique to humans and other vertebrates. The genome of the sea- squirt was... view more... (2004-03-31)
Yeast mimics severity of mutations leading to fatal childhood illness
Scientists report that human gene mutations expressed in yeast cells can predict the severity of Batten Disease, a fatal nervous system disorder that begins during childhood. view more (2008-12-22)
Gene Test Could Reduce Unnecessary Treatment For Women With Breast Cancer (pp 340, 362)
In this week's issue of THE LANCET, US researchers describe how gene expression profiles could determine whether or not women with breast cancer would respond to docetaxel treatment. Women who are likely to be resistant to the drug could be given alternative treatment. Chemotherapy or hormonal treatment after surgery for breast cancer is crucial... view more... (2003-07-30)
U-M researchers identify gene involved in breast cancer
Researchers at the University of Michigan Comprehensive Cancer Center have identified a gene linked to the development of an aggressive form of breast cancer. view more (2007-07-27)
New strategy rapidly identifies cancer targets
In a step toward personalized medicine, Howard Hughes Medical Institute investigator Brian J. Druker and colleagues have developed a new technique to identify previously unknown genetic mutations that can trigger cancerous growth. view more (2006-07-17)
Genes, environment, or chance?
Biologists attribute variations among individual organisms to differences in genes or environment, or both. But a new study of nematode worms with identical genes, raised in identical environments, has revealed another factor: chance. view more (2010-02-19)
Unique soybean lines hold promise for producing allergy-free soybeans
Researchers have isolated two Chinese soybean lines that grow without the primary protein linked to soy allergies in children and adults. view more (2006-05-05)
Three new species of lemurs identified
Researchers have identified three new species of lemurs, the small, big-eyed primates native to the island of Madagascar. view more (2006-02-23)
Scientists Discover Cause Of Leukaemia That Halted Treatment Trial For 'Baby-in-a-Bubble' Syndrome
Medical Research Council (MRC) scientists have helped establish the cause of the leukaemia which developed in two young patients taking part in a pioneering gene therapy trial to treat the fatal 'baby-in-a-bubble' syndrome, severe combined immunodeficiency (X-SCID). The trial at the Necker-Enfants Malades clinic in Paris was stopped last year due... view more... (2003-10-16)
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