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First Parkinson's Gene Therapy Patient Passes One Year
The first ever patient to have undergone gene therapy for Parkinson's appears to have come through phase I without a hitch, suggesting that the therapy is safe and effective, reports Marina Murphy in Chemistry & Industry.   view more (2004-09-02)

Polymers are promising tools for gene therapy
New methods are being developed to cure illnesses with the aid of gene therapy. Polymer technology provides new and versatile possibilities for administering gene doses. "Polymers are used to pack the gene to be transferred into particles of the size of a ten thousandth of a millimetre. These... view more (2002-04-24)

Gene therapy completely suppresses ovarian cancer growth in animal model
University of Pittsburgh School of Medicine researchers have used gene therapy to either completely abolish or significantly inhibit tumor progression in a mouse model of ovarian cancer.   view more (2006-06-05)

First gene therapy for heart failure offered at NewYork-Presbyterian/Columbia
Could injecting a gene into a patient with severe heart failure reverse their disabling and life-threatening condition? Physician-scientists are setting out to answer that question in a first-ever clinical trial of gene therapy to treat severe heart failure.   view more (2008-06-19)

Gene therapy slows progression of fatal neurodegenerative disease in children
Gene therapy to replace the faulty CLN2 gene, which causes a neurodegenerative disease that is fatal by age 8-12 years, was able to slow significantly the rate of neurologic decline in treated children.   view more (2008-05-14)

"Suicide gene" injection shrinks cancer growth
Injectable "suicide gene" therapy may be a highly effective way of preventing colon cancer from spreading (metastasising), finds research in Gut. Human colon cancer carries a high risk of death because it is often not found in the early stages and readily spreads to the liver, but also the lungs... view more (2002-02-08)

Gene therapy 'turns off' mutation linked to Parkinson's disease
A group of Northwestern University researchers is developing a novel gene therapy aimed at selectively turning off one of the genes involved in the development of Parkinson's disease.   view more (2006-01-19)

MRC Research Offers Hope of Treatment for People with Duchenne Muscular Dystrophy
A new approach which effectively patches over genetic defects offers hope of treatment to people with the terminal illness, Duchenne muscular dystrophy. This is the conclusion of research led by Dr Qi Long Lu and Professor Terence Partridge at the Medical Research Council's Clinical Sciences... view more (2003-07-04)

New study shows that therapeutic gene expression can be sustainable for 1 year
Researchers at the Board of Governors Gene Therapeutics Research Institute at Cedars-Sinai Medical Center have shown for the first time that it is possible to sustain therapeutic gene expression in the central nervous system for up to a year, even in the presence of an anti-viral immune response... view more (2007-10-26)

UVa researchers restore genes in human inner ear cells
Researchers at the University of Virginia Health System have discovered a way to transfer genes, which they hope will restore hearing, into diseased tissue of the human inner ear.   view more (2007-06-14)

Gene therapy accelerates healing of damaged skeletal muscle
University of Pittsburgh School of Medicine researchers have successfully used gene therapy to accelerate muscle regeneration in experimental animals with muscle damage, suggesting this technique may be a novel and effective approach for improving skeletal muscle healing, particularly for serious... view more (2006-06-05)

Scientists Discover Cause Of Leukaemia That Halted Treatment Trial For 'Baby-in-a-Bubble' Syndrome
Medical Research Council (MRC) scientists have helped establish the cause of the leukaemia which developed in two young patients taking part in a pioneering gene therapy trial to treat the fatal 'baby-in-a-bubble' syndrome, severe combined immunodeficiency (X-SCID). The trial at the Necker-Enfants... view more (2003-10-16)

Gene therapy breakthrough offers hope to patients with inherited high cholesterol levels
New research published in BMC Molecular Biology explains how a new technique for introducing genes into mammalian cells using the virus responsible for warts could be a major step forward in developing gene therapy treatments for people with familial hypercholesterolemia (FH), a genetic disease... view more (2002-05-14)

Intravenous gene therapy protects normal tissue of mice during whole-body radiation
Gene therapy administered intravenously could be an effective agent to protect vital organs and tissues from the effects of ionizing radiation in the event of large-scale exposure from a radiological or nuclear bomb.   view more (2007-10-29)

For Stanford scientists, RNAi gene therapy takes two steps forward, one step back
Three years ago Mark Kay, MD, PhD, published the first results showing that a hot new biological phenomenon called RNA interference was an effective gene-therapy technique in mice.   view more (2006-05-25)

Gene therapy may protect normal tissues during radiation retreatment for lung cancer
Gene therapy could be used as an agent to protect normal tissues, including the esophagus and lung, from damage during a second administration of radiation therapy for non-small cell lung cancer.   view more (2005-10-17)

Gene therapy for muscular dystrophy fixes frail muscle cells in animal model, Stanford study finds
A new gene therapy technique that has shown promise in skin disease and hemophilia might one day be useful for treating muscular dystrophy, according to a new study by researchers at Stanford University School of Medicine.   view more (2005-12-27)

Henry Ford Hospital expands research on gene and radiation therapy for prostate cancer
Henry Ford Hospital is embarking on an expanded major clinical trial involving the use of gene therapy in combination with radiation therapy, to determine if the combined treatment is more effective than radiation therapy alone for patients with intermediate risk prostate cancer.   view more (2008-02-07)

Cancer Gene Radiation Therapy Discovery
Dr Tracy Robson, a lecturer in molecular radiation science at the University's Jordanstown campus, has isolated a novel gene, called DIR-1, which can alter a tumour cell's susceptibility to radiation therapy.   view more (1999-09-20)

First evidence of gene therapy for abnormal blood vessel growth in newborns
The first evidence of the potential for gene therapy to treat eye disease that stems from abnormal blood vessel growth is revealed in research published in the British Journal of Ophthalmology. Gene therapy is a relatively new and much heralded therapeutic approach. But despite the advances in... view more (2001-07-18)

Gene therapy to lower blood pressure just enough
A newly developed virus that introduces a blood pressure-lowering gene into cells and enables that gene to maintain blood pressure at healthy levels for four months promises to take gene therapy for the disorder a step closer to reality.   view more (2005-09-28)

Intravenous gene therapy protects normal tissue of mice during whole-body radiation
Gene therapy administered intravenously could be used as an agent to protect vital organs and tissues from the effects of ionizing radiation in the event of large-scale exposure from a radiological or nuclear bomb.   view more (2006-11-08)

VCU Massey Cancer Center and VCU Institute of Molecular Medicine Researchers Publish Findings of a New Chemoprevention Gene Therapy That Kills Pancreatic Cancer Cells
Researchers at the Virginia Commonwealth University Massey Cancer Center and the VCU Institute of Molecular Medicine have published findings that implicate a new chemoprevention gene therapy (CGT) for preventing and treating pancreatic cancer, one of the most lethal and treatment-resistant forms of... view more (2008-08-06)

Tissue engineering technique does not cause tumor growth
A gene therapy approach used in creating new arteries for older patients does not appear to cause cancer, according to a pilot study by Yale School of Medicine researchers reported in the Proceedings of the National Academy of Sciences.   view more (2006-03-01)

Gene, stem cell therapy only needs to be 50 percent effective to create a healthy heart
Heart disease is the leading cause of death in the United States and greatly affects the quality and length of life for individuals with specific forms of muscular dystrophy.   view more (2007-11-01)
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