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Gene therapy breakthrough offers hope to patients with inherited high cholesterol levels
New research published in BMC Molecular Biology explains how a new technique for introducing genes into mammalian cells using the virus responsible for warts could be a major step forward in developing gene therapy treatments for people with familial hypercholesterolemia (FH), a genetic disease that affects around 12 million people worldwide.... view more... (2002-05-14)
Intravenous gene therapy protects normal tissue of mice during whole-body radiation
Gene therapy administered intravenously could be an effective agent to protect vital organs and tissues from the effects of ionizing radiation in the event of large-scale exposure from a radiological or nuclear bomb. view more (2007-10-29)
For Stanford scientists, RNAi gene therapy takes two steps forward, one step back
Three years ago Mark Kay, MD, PhD, published the first results showing that a hot new biological phenomenon called RNA interference was an effective gene-therapy technique in mice. view more (2006-05-25)
Gene therapy may protect normal tissues during radiation retreatment for lung cancer
Gene therapy could be used as an agent to protect normal tissues, including the esophagus and lung, from damage during a second administration of radiation therapy for non-small cell lung cancer. view more (2005-10-17)
Gene therapy for muscular dystrophy fixes frail muscle cells in animal model, Stanford study finds
A new gene therapy technique that has shown promise in skin disease and hemophilia might one day be useful for treating muscular dystrophy, according to a new study by researchers at Stanford University School of Medicine. view more (2005-12-27)
An effective target of biological therapy for hepatocellular carcinoma
It has been shown that constitutively activated STAT3 is detected in many HCC cell lines and tissues. This suggests that STAT3 is a promising molecular target for HCC gene therapy. view more (2009-06-15)
Cornell researchers identify a weak link in cancer cell armor
The seeming invincibility of cancerous tumors may be crumbling, thanks to a promising new gene therapy that eliminates the ability of certain cells to repair themselves. view more (2009-11-13)
Henry Ford Hospital expands research on gene and radiation therapy for prostate cancer
Henry Ford Hospital is embarking on an expanded major clinical trial involving the use of gene therapy in combination with radiation therapy, to determine if the combined treatment is more effective than radiation therapy alone for patients with intermediate risk prostate cancer. view more (2008-02-07)
Cancer Gene Radiation Therapy Discovery
Dr Tracy Robson, a lecturer in molecular radiation science at the University's Jordanstown campus, has isolated a novel gene, called DIR-1, which can alter a tumour cell's susceptibility to radiation therapy. view more (1999-09-20)
First evidence of gene therapy for abnormal blood vessel growth in newborns
The first evidence of the potential for gene therapy to treat eye disease that stems from abnormal blood vessel growth is revealed in research published in the British Journal of Ophthalmology. Gene therapy is a relatively new and much heralded therapeutic approach. But despite the advances in molecular genetics, attempts to target organs or... view more... (2001-07-18)
Gene therapy to lower blood pressure just enough
A newly developed virus that introduces a blood pressure-lowering gene into cells and enables that gene to maintain blood pressure at healthy levels for four months promises to take gene therapy for the disorder a step closer to reality. view more (2005-09-28)
Intravenous gene therapy protects normal tissue of mice during whole-body radiation
Gene therapy administered intravenously could be used as an agent to protect vital organs and tissues from the effects of ionizing radiation in the event of large-scale exposure from a radiological or nuclear bomb. view more (2006-11-08)
VCU Massey Cancer Center and VCU Institute of Molecular Medicine Researchers Publish Findings of a New Chemoprevention Gene Therapy That Kills Pancreatic Cancer Cells
Researchers at the Virginia Commonwealth University Massey Cancer Center and the VCU Institute of Molecular Medicine have published findings that implicate a new chemoprevention gene therapy (CGT) for preventing and treating pancreatic cancer, one of the most lethal and treatment-resistant forms of cancer. view more (2008-08-06)
Vision improvement after gene therapy maintained at 1 year for inherited retinal blindness
One year after a trio of young adults received gene therapy for an inherited form of blindness, researchers have documented that the patients are still experiencing the same level of remarkable vision improvements previously measured within weeks. view more (2009-08-13)
Tissue engineering technique does not cause tumor growth
A gene therapy approach used in creating new arteries for older patients does not appear to cause cancer, according to a pilot study by Yale School of Medicine researchers reported in the Proceedings of the National Academy of Sciences. view more (2006-03-01)
Gene, stem cell therapy only needs to be 50 percent effective to create a healthy heart
Heart disease is the leading cause of death in the United States and greatly affects the quality and length of life for individuals with specific forms of muscular dystrophy. view more (2007-11-01)
Tiny magnets offer breakthrough in gene therapy for cancer
A revolutionary cancer treatment using microscopic magnets to enable 'armed' human cells to target tumours has been developed by researchers funded by the Biotechnology and Biological Sciences Research Council (BBSRC). view more (2008-04-18)
Scientist clears hurdles for muscular dystrophy therapy
Approximately 250,000 people in the United States have some form of muscular dystrophy. Duchenne muscular dystrophy (DMD) is the most common type of the disease, predominantly affecting males. view more (2008-10-29)
Chemistry & Industry - Issue 3 Cover Date 4 February 2002
NEWS view more (2002-01-31)
A potential route for human tumor gene therapy
The type 1 Na+/H+ exchanger (NHE1) is a transmembrane protein found in all eukaryotic cells. One of its functions is to evacuate excessive H+ in the cytoplasm by means of Na+-H+ exchange, resulting in stable intracellular pH value. view more (2008-05-21)
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