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Oxford BioMedica Describes the Manufacturing Process for Prosavin at Bio2003
Oxford, UK: 23 June 2003. Oxford BioMedica announced today the details of its novel manufacturing process for ProSavin®, for the treatment of Parkinson's disease, that will be presented at the BIO 2003 Annual Convention in Washington DC on 25 June. The new manufacturing process has the capacity to satisfy all of the Company's requirements up... view more... (2003-06-23)
Boston Univeristy bioengineers devise 'dimmer swith' to regulate gene expression in mammal cells
Three Boston University biomedical engineers have created a genetic dimmer switch that can be used to turn on, shut off, or partially activate a gene's function. view more (2007-07-27)
New Discovery Raises Doubts About Use of Certain Targeted Therapies in Bladder Cancer
Researchers at the University of Virginia Health System have found that one of the genes commonly thought to promote the growth and spread of some types of cancers is in fact beneficial in bladder cancer - a major discovery that could significantly alter the way bladder cancers are treated in the future. view more (2009-03-26)
Gene expression in labor; and more — press release from PLoS Medicine
A Research Article, Perspective and e-Letter all published today discuss the use of microarrays to discover genes involved in childbirth. The three papers highlight the complexity of such gene expression analyses but also how crucial it is to make original data available for reanalysis. view more (2006-06-13)
One man's junk may be a genomic treasure
Scientists have only recently begun to speculate that what's referred to as "junk" DNA - the 96 percent of the human genome that doesn't encode for proteins and previously seemed to have no useful purpose - is present in the genome for an important reason. view more (2007-07-13)
First clinical trial of gene therapy for muscular dystrophy now under way
The first gene therapy human trial in the United States for a form of muscular dystrophy is under way. view more (2006-03-30)
Genes influence effectiveness of weight-loss drug
Obese patients with a specific genetic make-up lose more weight when taking the weight loss drug sibutramine and undergoing behavioral therapy compared to those without this genetic make-up, reports a new study in Gastroenterology, the official journal of the American Gastroenterological Association (AGA) Institute. view more (2008-10-02)
Iowa State researcher studies gene families to explore diversity and evolution
Theoretical biologist Stephen Proulx studies gene families to explore how genomes become diverse and evolve. view more (2006-08-01)
Jefferson scientists uncover role of cancer stem cell marker: controlling gene expression
Scientists at Jefferson's Kimmel Cancer Center in Philadelphia have made an extraordinary advance in the understanding of the function of a gene previously shown to be part of an 11-gene "signature" that can predict which tumors will be aggressive and likely to spread. view more (2008-01-18)
Salt of the Earth
A yeast gene responsible for salt tolerance has successfully been used to grow tobacco in a salty environment lethal to most plants. Dr Janey Henderson and Professor Phil Harris from Coventry University inserted the halotolerance gene HAL1 from yeast into a tobacco plant. HAL1 has previously been shown to confer salt tolerance in transgenic tomato... view more... (2001-04-04)
Novel lipoplex nanoparticle to be used in 1st human trial treating advanced solid cancer
The first clinical trial of a biologic nanoparticle designed to give back to cancer patients the tumor-busting gene they have lost is expected to start in September at Georgetown University Medical Center. view more (2005-08-25)
Fewer wrinkles and firmer skin linked to earlier use of estrogen therapy
Long-term hormone estrogen therapy used earlier in menopause is associated with fewer wrinkles and less skin rigidity in postmenopausal women, Yale School of Medicine researchers report in the August issue of Fertility and Sterility. view more (2005-08-29)
Manual therapy is effective treatment for neck pain
Manual therapy is more effective and less costly for treating neck pain than physiotherapy or care by a general practitioner, claim researchers in this week's BMJ. The study involved 183 patients recruited by 42 general practitioners in the Netherlands. All patients were aged 18-70 years and had suffered neck pain for at least two weeks. Sixty... view more... (2003-04-23)
Urologist plays key role in determining use of hormone therapy in prostate cancer
The urologist a patient sees may be a more important factor than the tumor characteristics or the patient's other characteristics in determining the use of hormonal therapy for prostate cancer. view more (2006-06-21)
Time to reassess the value of HRT
It may be time to reassess the value of hormone replacement therapy, following evidence that it reduces the effectiveness of breast screening and causes breast cancer in women over the age of 50, says a leading breast surgeon in this week's BMJ. Increasing numbers of women in their 50s and 60s are using hormone replacement therapy to alleviate... view more... (2001-12-12)
Chemical genomic screening identifies novel therapeutic strategies for cancer
A sophisticated new chemical genetic screening strategy that serves as a tool for identifying anticancer compounds may significantly enhance the drug discovery process. view more (2006-09-29)
Scientists identify a gene that may suppress colorectal cancer
In today's online edition of Genome Research, a husband-and-wife research team from Thomas Jefferson University report the discovery of a gene that, when mutated, may suppress colorectal cancer. view more (2007-03-22)
UCLA researchers develop T-cells from human embryonic stem cells
Researchers from the UCLA AIDS Institute and the Institute for Stem Cell Biology and Medicine have demonstrated for the first time that human embryonic stem cells can be genetically manipulated and coaxed to develop into mature T-cells, raising hopes for a gene therapy to combat AIDS. view more (2006-07-05)
Boosting its infectivity turns benign virus into good gene therapy carrier for cystic fibrosis
Researchers from the University of California, Berkeley, and the University of Iowa have turned a relatively benign virus into a highly infectious form that is ideal as a carrier for gene therapy. view more (2009-02-17)
New gene linked to bipolar disorder
A new gene linked to both depression and bipolar disorder has been identified by UCL (University College London) and Danish researchers. view more (2006-10-04)
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