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Suppressing cancer with a master control gene
Starting with the tiny fruit fly and then moving into mice and humans, researchers at VIB and K. U. Leuven show that expression of the same gene suppresses cancer in all three organisms. view more (2009-02-23)
Gene therapy advance treats hemophilia in mouse models
A virus that typically infects insects could help with the development of gene therapy treatment for Hemophilia A, a condition in which even a bump on the knee can cause serious internal bleeding in people. view more (2005-08-23)
Three-in-one virus killer prevents common, often fatal infections
A novel combination therapy drastically reduces the infection rate of three viruses - and risk of death - in transplant patients with compromised immune systems. view more (2006-10-27)
Researchers identify cancer-causing gene in many colon cancers
Demonstrating that despite the large number of cancer-causing genes already identified, many more remain to be found, scientists at Dana-Farber Cancer Institute have linked a previously unsuspected gene, CDK8, to colon cancer. view more (2008-09-15)
Caltech researchers show efficacy of gene therapy in mouse models of Huntington's disease
Researchers at the California Institute of Technology (Caltech) have shown that a highly specific intrabody (an antibody fragment that works against a target inside a cell) is capable of stalling the development of Huntington's disease in a variety of mouse models. view more (2009-11-02)
Fragile X retardation syndrome corrected in mice
Researchers working with mice have significantly alleviated a wide range of abnormalities due to fragile X syndrome by altering only a single gene, countering the effects of the fragile X mutation. view more (2007-12-20)
Gene responsible for common hearing loss identified for first time
A gene responsible for the single most common cause of hearing loss among white adults, otosclerosis, has been identified for the first time. view more (2007-06-18)
Breast Cancer Gene Reviewed
PRESS CONFERENCE - 0930 H Thursday 26 September at Cancer Research UK, 44 Lincoln's Inn Fields, London WC2A 3PX, UK; Further information from Cancer Research UK Press Office (see below). A review article in this week's issue of THE LANCET assesses the impact of BRCA1 gene mutations-known to be strongly associated with an increased risk of breast... view more... (2002-09-25)
New patient satisfaction study with budesonide/formoterol combination therapy
A new open-label study evaluated patient satisfaction with budesonide/formoterol combination therapy and fluticasone/salmeterol combination therapy. view more (2008-05-21)
Experimental Parkinson's therapy may have robust weight-loss effect
A growth factor used in clinical experiments to rescue dying brain cells in Parkinson patients may cause unwanted weight loss if delivered to specific areas of the brain, according to University of Florida researchers in the March online edition of Molecular Therapy. view more (2009-03-25)
Vitamin K discovery may lead to new treatments for patients at risk from blood clots
Medical Research Council (MRC) scientists have discovered more about the role that vitamin K plays in the complicated process of how blood clots. Their work, published in Nature, may lead to new treatments for patients at risk from blood clots, including those who have had heart attacks, have coronary artery disease, irregular heart beats, or have... view more... (2004-02-04)
Targeting a key enzyme with gene therapy reversed course of Alzheimer's disease in mouse models
In mice, that had been genetically engineered to develop Alzheimer's disease, scientists were able to reverse the rodents' memory loss by reducing the amount of an enzyme that is crucial for the development of Alzheimer's disease. view more (2005-09-22)
Cancer Conundrum Cracked
Cancer researchers at the University of Dundee have just turned a common cancer belief on its head saying that a group of proteins previously believed to cause cancer can also be used in the fight against cancer. Dr Neil Perkins and his team in the School of Life Sciences have identified that NF-kappaB * a group of proteins present in every cell... view more... (2004-03-25)
Gene therapy shows early promise for treating obesity
With obesity reaching epidemic levels, researchers at the Ohio State University Medical Center are studying a potentially long-term treatment that involves injecting a gene directly into one of the critical feeding and weight control centers of the brain. view more (2009-03-10)
Dardarina, the Basque gene for Parkinson's
Research began when doctors discovered that various members of the same family had Parkinson's. There are many kinds of Parkinson's and some are hereditary. Now, a group of scientists have identified the gene which produces the hereditary Park8 variant of Parkinson's in four Basque families and another in the UK. The gene is called dardarina; a... view more... (2004-11-04)
Gene therapy with growth factor seems promising therapy for incurable muscle disorder ALS
ALS is an incurable paralysing muscle disorder affecting five in every one hundred thousand people. The disease mainly strikes healthy people in the most active period of their life, without any warning or family history. Researchers from VIB (the Flanders Interuniversity Institute for Biotechnology), lead by Prof. Peter Carmeliet (K.U.Leuven)... view more... (2004-05-27)
Bats add their voice to the FOXP2 story
When it comes to the FOXP2 gene, humans have had most to shout about. Discoveries that mutations in this gene lead to speech defects and that the gene underwent changes around the time language evolved both implicate FOXP2 in the evolution of human language. view more (2007-09-19)
Gene therapy reverses genetic mutation responsible for heart failure in muscular dystrophy
University of Pittsburgh investigators have for the first time used gene therapy to successfully treat heart failure and other degenerative muscle problems in an animal model that is genetically susceptible to a human muscular dystrophy. view more (2005-10-26)
Occupational therapy improves quality of life for dementia patients and their carers
Occupational therapy can help to improve the ability of people with dementia to perform daily activities and can also reduce the pressure on their caregivers. view more (2006-11-17)
Gene therapy research in developing world raises ethical red flags: experts
Early stage gene therapy clinical trials are recruiting patients from the developing world, providing medically deprived populations access to interventions that show promise but have largely unknown effects in humans. view more (2008-07-10)
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