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Scripps research team reverses Friedreich's ataxia defect in cell culture
In the new study, the researchers tested a variety of compounds that inhibited a class of enzymes known as histone deacetylases in a cell line derived from blood cells from a Fredreich's ataxia sufferer. view more (2006-08-22)
Pol3 mutation disrupts organ growth
The cellular mechanism that turns DNA into all of the thousands of proteins that make up a human body is itself both intricate and interesting. view more (2007-11-27)
HATS off to combat asthma
Two University of Nottingham studies exploring the causes and treatment of asthma and Chronic Obstructive Pulmonary Disease (COPD) could lead to the development of drugs to battle these debilitating conditions. view more (2007-12-05)
Getting down to cancer basics
Researchers have identified a new cancer gene - one that is common to many cancers and affects the most basic regulation of our genes. The new example - a gene on the X chromosome called UTX - is found in 10% of cases of multiple myeloma and 8% of esophageal cancers. view more (2009-03-30)
Deep sequencing study reveals new insights into human transcriptome
In a collaborative project scientists from the Max-Planck-Institute for Molecular Genetics in Berlin (MPI MolGen), Germany and Genomatix with a business in Munich, Germany and Ann Arbor, MI, USA, applied next generation sequencing and analysis methods to generate an unprecedented view at the human transcriptome. view more (2008-07-09)
Gene expression in labor; and more — press release from PLoS Medicine
A Research Article, Perspective and e-Letter all published today discuss the use of microarrays to discover genes involved in childbirth. The three papers highlight the complexity of such gene expression analyses but also how crucial it is to make original data available for reanalysis. view more (2006-06-13)
Stem cell therapy for spinal injury
Researchers at Karolinska Institutet have shown how the transplantation of stem cells improves recovery from spinal injury. However, a painful condition can also develop, which can be prevented if the stem cells are supplemented with a certain gene that controls their maturing process. The results are important for planning of stem cell therapy... view more... (2005-02-13)
Research Reveals Secrets of Alcohol's Effect on Brain Cells
Alcohol triggers the activation of a variety of genes that can influence the health and activity of brain cells, and new research from Weill Cornell Medical College in New York City sheds light on how that process occurs. view more (2007-12-10)
Scientists show gene mutation may cause immature lungs in newborns
Scientists have identified a gene critical to lung maturation in newborns and the production of surfactant, which lines lung tissues and prevents the lungs from collapsing. view more (2008-11-25)
Technology identified could reduce the spread of rice virus
Building on plant virus research started more than 20 years ago, a biologist at Washington University in St. Louis and his colleague at the Donald Danforth Plant Science Center in St. Louis have discovered a technology that reduces infection by the virus that causes Rice Tungro Disease, a serious limiting factor for rice production in Asia. view more (2009-02-11)
Iowa State researcher studies gene families to explore diversity and evolution
Theoretical biologist Stephen Proulx studies gene families to explore how genomes become diverse and evolve. view more (2006-08-01)
Salt of the Earth
A yeast gene responsible for salt tolerance has successfully been used to grow tobacco in a salty environment lethal to most plants. Dr Janey Henderson and Professor Phil Harris from Coventry University inserted the halotolerance gene HAL1 from yeast into a tobacco plant. HAL1 has previously been shown to confer salt tolerance in transgenic tomato... view more... (2001-04-04)
Who found some new mechanisms of HBV virulence?
This dreadful HBV is small in size. The genome of this virus is a partial double stranded circle. When made fully double stranded, this genome carries about 3000 base pairs, compared to 200 kilo base pairs of the genome of the smallpox virus. view more (2008-02-25)
Properties of Unusual Virus Revealed in Researchers
A team of researchers from Penn State University and the University of Chicago has uncovered clues that may explain how and why a particular virus, called N4, injects an unusual substance -- an RNA polymerase protein -- into an E. coli bacterial cell. The results, which are published in the current issue of the journal Molecular Cell, contribute... view more... (2008-12-09)
Two Genes Are Important Key to Regulating Immune Response
A research team at Weill Cornell Medical College in New York City has identified two genes that may be crucial to the production of an immune system cytokine called interleukin-10 (IL-10). view more (2008-01-02)
New gene linked to bipolar disorder
A new gene linked to both depression and bipolar disorder has been identified by UCL (University College London) and Danish researchers. view more (2006-10-04)
A potential targeting gene therapy for developing HCV
Gene therapy has emerged as a novel approach to combat HCV infection in the last few years. view more (2009-07-16)
New understanding of Ewing's sarcoma suggests novel treatment strategy
Using molecular and cell-based models, researchers at Georgetown University Medical Center have refined the picture of how a cancer-promoting protein associated with Ewing's sarcoma functions. view more (2006-06-01)
Revealing the machinery underlying the 'plastic' juvenile brain
Among the central mysteries of neurobiology is what properties of the young brain enable it to so adeptly wire itself to adapt to experience—a quality known as plasticity. view more (2007-03-01)
Targeting the dosage compensation complex
Three independent research papers in the April 1 issue of G&D detail the chromosome-wide binding of the Drosophila dosage compensation complex (DCC) to the single male X chromosome, shedding new light on the mechanism of DCC targeting. view more (2006-03-17)
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