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A solution to Darwin's 'mystery of the mysteries' emerges from the dark matter of the genome
Biological species are often defined on the basis of reproductive isolation. Ever since Darwin pointed out his difficulty in explaining why crosses between two species often yield sterile or inviable progeny (for instance, mules emerging from a cross between a horse and a donkey), biologists have struggled with this question.   view more (2009-10-27)

First Parkinson's Gene Therapy Patient Passes One Year
The first ever patient to have undergone gene therapy for Parkinson's appears to have come through phase I without a hitch, suggesting that the therapy is safe and effective, reports Marina Murphy in Chemistry & Industry.   view more (2004-09-02)

Boston University biomedical engineers teach bacteria to count
Biomedical engineers at Boston University have taught bacteria how to count. Professor James J. Collins and colleagues have wired a new sequence of genes that allow the microbes to count discrete events, opening the door for a host of potential applications, which could include drug delivery and sensing environmental hazards.   view more (2009-05-29)

Dardarina, the Basque gene for Parkinson's
Research began when doctors discovered that various members of the same family had Parkinson's. There are many kinds of Parkinson's and some are hereditary. Now, a group of scientists have identified the gene which produces the hereditary Park8 variant of Parkinson's in four Basque families and another in the UK. The gene is called dardarina; a... view more... (2004-11-04)

Polymers are promising tools for gene therapy
New methods are being developed to cure illnesses with the aid of gene therapy. Polymer technology provides new and versatile possibilities for administering gene doses. "Polymers are used to pack the gene to be transferred into particles of the size of a ten thousandth of a millimetre. These polymers effectively transport the transferable... view more... (2002-04-24)

New type of genetic change identified in inherited cancer
Duke University Medical Center and National Cancer Institute scientists have discovered that a novel genetic alteration - a second copy of an entire gene - is a cause of familial chordoma, an uncommon form of cancer arising in bones and frequently affecting the nervous system.   view more (2009-10-05)

Bats add their voice to the FOXP2 story
When it comes to the FOXP2 gene, humans have had most to shout about. Discoveries that mutations in this gene lead to speech defects and that the gene underwent changes around the time language evolved both implicate FOXP2 in the evolution of human language.   view more (2007-09-19)

U of Minnesota researchers find master gene behind blood vessel development
In a first of its kind discovery, University of Minnesota researchers have identified the "master gene" behind blood vessel development. Better understanding of how this gene operates in the early stages of development may help researchers find better treatments for heart disease and cancer.    view more (2009-02-05)

UCSF team closer to creating safe embryonic-like stem cells
A team of UCSF researchers has for the first time used tiny molecules called microRNAs to help turn adult mouse cells back to their embryonic state.   view more (2009-04-13)

Genetic interactions are the key to understanding complex traits
In recent years, genetic studies have uncovered hundreds of DNA variations linked to common diseases, such as cancer or diabetes, raising the prospect that scientists can gauge disease risk based on information in an individual's genome.   view more (2009-01-23)

Traditional herbal medicine kills pancreatic cancer cells, Jefferson researchers report
An herb used in traditional medicine by many Middle Eastern countries may help in the fight against pancreatic cancer, one of the most difficult cancers to treat.   view more (2008-05-19)

Would you like gene chips with your salad ?
The first public release of plant gene chip information is being launched at the Society for Experimental Biology conference in Swansea on Friday 12th April. Scientists from the Nottingham Arabidopsis Stock Centre (NASC), part of a multi-million pound resource network, will announce a newly accessible plant gene chip database which is available... view more... (2002-04-11)

Understanding mental illness through gene-environment interactions
Biological Psychiatry, published by Elsevier, is very pleased to present a special section of its February 1st issue devoted to fundamental new insights into epigenetics, a field of research devoted to understanding how the environment can produce long-lasting or even heritable changes in gene function without altering the DNA sequence.   view more (2009-03-17)

Il-22 gene delivers the goods and decreases intestinal inflammation
There are two major types of inflammatory bowel disease (IBD), Crohn disease (CD) and ulcerative colitis (UC).   view more (2008-01-03)

Molecular steps involved in the creation of gene-silencing MicroRNAs identified
First discovered only a few brief years ago, microRNAs are small, remarkably powerful molecules that appear to play a pivotal role in gene silencing, one of the body's main strategies for regulating its genome. A scant 22 nucleotides in length, miRNAs appear to work by binding to and somehow interfering with messenger RNA, itself responsible for... view more... (2005-06-23)

Carnegie Mellon University research reveals how cells process large genes
Important messages require accurate transmission. Big genes are especially challenging because they combine many coding segments (exons) that lie between long stretches of non-coding elements (introns).   view more (2005-08-24)

Gene variants reveal susceptibility to cardiovascular disease
Variations in a gene that acts as a switch to turn on other genes may predispose individuals to heart disease, an international team of researchers led by Duke University Medical Center scientists has discovered.   view more (2006-08-25)

Mouse gene shows new mechanism behind cardiac infarction in man
A gene that, in different variants, increases or decreases the level of atherosclerosis has been identified in mice. The corresponding human gene has been shown to play a role in the development of myocardial infarction. The results of the study is published this week on Nature Genetics Online.   view more (2005-03-08)

Process controlling T cell growth and production identified
Identifying one of the processes that plays a role in naïve and memory T-cells' growth and production could one day lead to better vaccines and possibly more effective cancer immunotherapy.   view more (2009-05-04)

Study associates 11 new gene sites with cholesterol, triglyceride levels
An international research team has identified 11 novel locations in the human genome where common variations appear to influence cholesterol or triglyceride levels, bringing the total number of lipid-associated genes to 30.   view more (2008-12-08)
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