Gene Transcription Current Events | Gene Transcription News | 8
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Key root-development pathway mapped using advanced genomic technique
Biologists have vastly expanded understanding of the biological machinery controlling the intricate process by which plant roots burgeon from single cells into complex tissues. view more (2006-05-05)
Cold Spring Harbor Laboratory Scientists Devise Potential Approach To Treat Spinal Muscular Atrophy
In the neuromuscular disease called spinal muscular atrophy, or SMA, a protein deficiency caused by a single gene mutation leads to serious damage in growing nerve cells and the muscles they control. view more (2008-04-07)
Scientists shed light on inner workings of human embryonic stem cells
Scientists at UC Santa Barbara have made a significant discovery in understanding the way human embryonic stem cells function. view more (2009-05-01)
Genes in rheumatoid arthritis
A paper published this week in the open access journal PLoS Medicine provides strong evidence that one specific part of the genome is associated with rheumatoid arthritis. view more (2007-09-18)
Novel mouse gene reduces major pathologies associated with Alzheimer's disease
A new study reveals that a previously undiscovered mouse gene reduces the two major pathological perturbations commonly associated with Alzheimer's disease (AD). view more (2009-11-12)
Researchers identify new anti-tumor gene
Researchers from Virginia Commonwealth University have identified a new anti-tumor gene called SARI that can interact with and suppress a key protein that is overexpressed in 90 percent of human cancers. The discovery could one day lead to an effective gene therapy for cancer. view more (2008-12-17)
Newly-discovered mechanism can explain the Beckwith-Wiedemann syndrome
Researchers from Uppsala University have discovered a mechanism that silences several genes in a chromosome domain. The findings, published in today's on-line issue of Molecular Cell, have implications in understanding the human disorder Beckwith-Wiedemann syndrome. view more (2008-10-27)
MDC researchers unravel key mechanism in pathogenesis of osteoporosis
Osteoporosis, or bone loss, is a disease that is most common in the elderly population, affecting women more often than men. view more (2009-05-15)
What is the mechanism of the chronic radiation enteritis?
The use of radiation therapy to treat cancer inevitably involves exposure of normal tissues. view more (2008-12-23)
Jefferson scientists uncover role of cancer stem cell marker: controlling gene expression
Scientists at Jefferson's Kimmel Cancer Center in Philadelphia have made an extraordinary advance in the understanding of the function of a gene previously shown to be part of an 11-gene "signature" that can predict which tumors will be aggressive and likely to spread. view more (2008-01-18)
LSUHSC research may benefit diabetes by increasing understanding of how to control islet cell growth
Michael Lan, PhD, Professor of Pediatrics and Genetics at LSU Health Sciences Center New Orleans, is the senior author of a paper revealing the molecular mechanism of how a protein determines the fate of the cells that make and release insulin. view more (2009-02-18)
Liver regeneration may be simpler than previously thought
The way the liver renews itself may be simpler than what scientists had been assuming. A new study, appearing in the April 13 issue of The Journal of Biological Chemistry, provides new information on the inner workings of cells from regenerating livers that could significantly affect the way physicians make livers regrow in patients with liver... view more... (2007-04-12)
Researchers see evidence of memory in the songbird brain
When a zebra finch hears a new song from a member of its own species, the experience changes gene expression in its brain in unexpected ways, researchers report. view more (2009-06-29)
Masterminding muscle development
Dr. Lizi Wu (Dana Farber Cancer Institute) and colleagues report on a critical role for one of the three mammalian mastermind genes (Maml1) in myogenesis - assigning that first biological function to the mammalian MAML Notch co-activators. view more (2006-02-28)
Yale scientists visualize the machinery of mRNA splicing
Recent research at Yale provided a glimpse of the ancient mechanism that helped diversify our genomes; it illuminated a relationship between gene processing in humans and the most primitive organisms by creating the first crystal structure of a crucial self-splicing region of RNA. view more (2008-04-07)
Finnish families guide to gene behind abnormal lipid levels and atherosclerosis
Coronary heart disease is the leading cause of death in Western societies. Unfavorable serum lipid levels, high cholesterol, high triglycerides and low high-density lipoprotein (HDL) cholesterol, are well-known risk factors for atherosclerosis and coronary heart disease. Familial combined hyperlipidemia (FCHL), characterized by these changes in... view more... (2004-03-01)
The evolution of gene regulation
Even microbes are governed by the principle of supply and demand - at least at the genetic level. Not all of their gene products, the blueprints for proteins, are required at all times. view more (2009-05-26)
Diabetes linked to male infertility; excess sugars in the body have direct effect on sperm quality
Diabetes in men has a direct effect on fertility, a scientist told the 24th annual conference of the European Society of Human Reproduction and Embryology today. view more (2008-07-09)
New study resolves the mysterious origin of Merkel cells
A new study resolves a 130-year-old mystery over the developmental origin of specialized skin cells involved in touch sensation. view more (2009-09-28)
New paper describes connections between Circadian and metabolic systems
A paper by University of Notre Dame biologist Giles Duffield and a team of researchers offers new insights into a gene that plays a key role in modulating the body's Circadian system and may also simultaneously modulate its metabolic system. view more (2009-11-13)
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