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Genetics determine optimal drug dose of common anticoagulant
Genetic testing can be used to help personalize the therapeutic dosage of warfarin, a commonly-used anticoagulant, according to research published in the September 1, 2007, issue of Blood, the journal of the American Society of Hematology. This result represents one of the first applications of using an individual's genetic information to guide... view more... (2007-08-22)

Study identifies multiple genetic risk factors for prostate cancer
A study led by researchers at the Keck School of Medicine of the University of Southern California (USC) and Harvard Medical School has identified seven genetic risk factors—DNA sequences carried by some people but not others—that predict risk for prostate cancer.   view more (2007-04-02)

Genetic Marker for Asthma Identified at Oxford
Researchers at Oxford University's Wellcome Trust Centre for Human Genetics have located a variant form of a polynucleotide sequence in the MHC region of chromosome 6p and identified its association with an increased secretion of TNF. Potential applications for this discovery include the diagnosis of asthma in patients, or a predisposition to... view more... (2003-02-10)

Eight new genes linked to diabetes; the understanding of a financial and health monster
Eight genes, normally associated with normal pancreatic functions, are linked with susceptibility to diabetes Type 2 reports a team of investigators in the last issue of the PLoS Biology Journal. In'™s Barroso and colleagues at the University of Cambridge, United Kingdom studied 71 genes on more than 2000 individuals, trying to correlate... view more... (2003-11-28)

Predicting risk of stroke from one's genetic blueprint
A new statistical model could be used to predict an individual's lifetime risk of stroke, finds a study from the Children's Hospital Informatics Program (CHIP). Using genetic information from 569 hospital patients, the researchers showed that their predictive model could estimate an individual's overall risk of cardioembolic stroke -- the most... view more... (2009-02-26)

Identification of genetic variants affecting age at menopause could help improve fertility treatment
For the first time, scientists have been able to identify genetic factors that influence the age at which natural menopause occurs in women.   view more (2009-05-26)

Study shows male homosexuality can be explained through a specific model of Darwinian evolution
Reporting in this week's PLoS ONE, an Italian research team, consisting of Andrea Camperio Ciani and Giovanni Zanzotto at the University of Padova and Paolo Cermelli at the University of Torino, found that the evolutionary origin and maintenance of male homosexuality in human populations could be explained by a model based around the idea of... view more... (2008-06-18)

American College of Medical Genetics makes genetic testing recommendations in new policy statement
Consumers are increasingly being marketed a broad range of genetic tests. Paternity tests at the drugstore-.Personal genome mapping-Gene tests to predict future baldness.   view more (2008-04-25)

People are unlikely to withdraw consent for genetic research
People are unlikely to withdraw consent for genetic research even when samples were taken many years ago, research in this week's BMJ suggests. In 1990 1583 randomly selected people in Sweden donated blood to a World Health Organisation project researching cardiovascular disorders and diabetes. Eleven years later, doctors sought their consent for... view more... (2002-09-18)

Europe-wide Study Seeks Causes Of Oral Cancers
Scientists from The University of Manchester are playing a key role in a major Europe-wide study - believed to be the largest of its kind - of cancers of the mouth, pharynx and larynx (throat) and oesophagus (gullet). Incidences of these cancers are increasing faster in the UK than almost anywhere else in western Europe. Every year, cancers of the... view more... (2003-02-04)

Study of neighborhoods points to modifiable factors, not race, in cancer disparities
While cities have shown considerable racial disparities in cancer survival, those racial disparities virtually disappear among smaller populations, such as neighborhoods within that city.   view more (2009-04-13)

Johns Hopkins researchers discover new schizophrenia gene
Researchers at the Johns Hopkins University School of Medicine are one gene closer to understanding schizophrenia and related disorders. Reporting in the Jan. 9 issue of the American Journal of Human Genetics, the team describes how a variation in the neuregulin 3 gene influences delusions associated with schizophrenia.   view more (2009-02-04)

Young age at first drink may affect genes and risk for alcoholism
The age at which a person takes a first drink may influence genes linked to alcoholism, making the youngest drinkers the most susceptible to severe problems.    view more (2009-09-21)

New gene variant identified for nondiabetic end stage renal disease in African-Americans
Scientists at Johns Hopkins schools of Public Health and Medicine have, for the first time, identified variants in the gene MYH9 that are associated with increased risk for non-diabetic end stage renal disease (ESRD,) which is the near-loss of kidney function leading to either dialysis of transplant. MYH9, located on the 22 chromosome, is the... view more... (2008-09-15)

Scientists find shared genetic link between the dental disease periodontitis and heart attack
The relationship between the dental disease periodontitis and coronary heart disease (CHD) has been known for several years.   view more (2009-05-26)

Increased risk of coronary heart disease among UK Indian Asians may be genetic
The increased rates of premature coronary heart disease among UK Indian Asians may be due to genetic or other as yet undiscovered risk factors, rather than the usual suspects, suggests research in Heart.   view more (1999-04-26)

A unique twin study on the increased cardiometabolic risk in obesity
Obesity and its many related health hazards have become a serious and growing problem worldwide. While environmental and lifestyle factors play a key role in the development of obesity, genetic variation may determine an individual's susceptibility to weight gain and to the rise of obesity-related health risks.   view more (2007-02-14)

Primary care practitioners need to become genetically literate
Increasing availability of DNA based tests and demand by patients for genetic information and advice mean that primary care practitioners will need to become genetically literate. A paper in this week's BMJ discusses the implications of genetic advances for primary care. Currently, the most important elements for primary care are prediction of... view more... (2001-04-24)

The genes involved in rheumatoid arthritis identified
The human genome has now been thoroughly screened in the hunt for the genetic causes of rheumatoid arthritis. The results, which both confirms previous hypotheses and turn the spotlight on entirely new genes, are presented in two articles in the prestigious New England Journal of Medicine.   view more (2007-09-07)

Susceptibility to Crohn's disease — an important new clue
Crohn's disease is a chronic relapsing inflammatory disorder of the intestinal tract that affects an estimated 0.15% of people in the developed world.   view more (2007-04-23)
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