Genetic Mutation Current Events | Genetic Mutation News | 6
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Dardarina, the Basque gene for Parkinson's
Research began when doctors discovered that various members of the same family had Parkinson's. There are many kinds of Parkinson's and some are hereditary. Now, a group of scientists have identified the gene which produces the hereditary Park8 variant of Parkinson's in four Basque families and another in the UK. The gene is called dardarina; a... view more... (2004-11-04)
Jefferson scientists uncover gene mutation that cuts colon polyps, may suppress cancer
Cancer biologists at the Kimmel Cancer Center at Jefferson have found a gene mutation that can dramatically reduce the number of colon polyps that develop, and in turn, potentially cut the risk of cancer. view more (2007-03-22)
Resistance and genetic sensitivity to sleeping sickness
Human African trypanosomiasis, more commonly called sleeping sickness, is induced by a parasite, the trypanosome, transmitted to humans by the bite of an insect, the glossinid tse-tse fly. view more (2006-10-16)
New view of cancer: 'Epigenetic' changes come before mutations
A Johns Hopkins researcher, with colleagues in Sweden and at the Fred Hutchinson Cancer Research Center, suggests that the traditional view of cancer as a group of diseases with markedly different biological properties arising from a series of alterations within a cell's nuclear DNA may have to give way to a more complicated view. view more (2005-12-22)
Study uncovers mechanism of drug resistance in form of lung cancer
Dana-Farber Cancer Institute researchers and their colleagues have demonstrated that a genetic error so scarce it can't be detected with some standard screening equipment is often responsible for the loss of effectiveness of front-line drugs against non-small cell lung cancer. view more (2006-09-07)
Body clock linked to diabetes and high blood sugar in new study
Diabetes and high levels of blood sugar may be linked to abnormalities in a person's body clock and sleep patterns, according to a genome-wide association study published today in the journal Nature Genetics. view more (2008-12-08)
Evolution of symbiosis
The aphid Acyrthosiphon pisum depends on a bacterial symbiont, Buchnera aphidicola, for amino acids it can't get from plants. The aphid, in turn, provides the bacterium with energy and carbon as well as shelter inside specialized cells. view more (2007-04-10)
A surprise 'spark' for pre-cancerous colon polyps
Researchers at Huntsman Cancer Institute (HCI) at the University of Utah studied the events leading to colon cancer and found that an unexpected protein serves as the "spark" that triggers formation of colon polyps, the precursors to cancerous tumors. view more (2009-05-15)
Scientists use Iceland's genealogical database to pinpoint the heritage of a deadly disease
A collaboration of scientists from Iceland and the United States has used Iceland's genealogical database* to trace the ancestors of patients suffering from hereditary cystatin C amyloid angiopathy (HCCAA). Analysis shows that the deadly mutation in the cystatin C gene, L68Q, derives from a common ancestor born roughly 18 generations ago, around... view more... (2008-06-20)
Canada high in ulcerative colitis and Crohn's cases: Is Canada too clean?
Canada has among the highest incidences of ulcerative colitis and Crohn's disease cases per capita in the world, a new study shows. view more (2006-08-24)
Cystic fibrosis testing -- next steps
Three reports describing advances in cystic fibrosis genetic testing appear in the May 2009 issue of The Journal of Molecular Diagnostics. view more (2009-04-28)
Dying of excitement
For neurons, overexcitement is deadly. To avoid this, brain cells must sop up unneeded neurotransmitters from the synapse through membrane-bound transporters. If these transporters fail, neurons and other brain cells get excited to death- a phenomenon that may contribute to brain damage during stroke and Alzheimer's disease. view more (2006-03-06)
Abnormal immune cells may cause unprovoked anaphylaxis
Two new clinical reports shed light on why some people suffer from recurrent episodes of idiopathic anaphylaxis--a potentially life-threatening condition of unknown cause characterized by a drop in blood pressure, fainting episodes, difficulty in breathing, and wheezing. view more (2007-11-12)
Study looks at psychological impact of gene test for breast cancer
Personal beliefs about inconclusive DNA testing for hereditary breast cancer are associated with cancer-related worry, and such beliefs are an especially strong predictor of whether women had been able to leave the period of DNA-testing behind. view more (2008-10-03)
Defective genes increase breast cancer risk in young women to a greater extent than previously estimated
A joint study between St Mary's Hospital, the Paterson Institute, Christie Hospital, The University of Manchester, Guys Hospital in London, and Cambridge University researching breast cancer has found that women with defects in certain genes have a higher chance of developing breast cancer when they are young than previous estimates. The report... view more... (2003-04-02)
New research helps explain why bird flu has not caused a pandemic
Bird flu viruses would have to make at least two simultaneous genetic mutations before they could be transmitted readily from human to human, according to research published today in PLoS ONE. view more (2009-11-19)
Yale study offers insight into possible cause of lymphoma
The immune system's powerful cellular mutation and repair processes appear to offer important clues as to how lymphatic cancer develops, Yale School of Medicine researchers report this week in Nature. view more (2008-02-15)
Researchers discover key mechanism to emergence of deadly strep bacteria
The incidence of serious strep infections has risen dramatically in the last three decades, and this increase is largely attributed to the spread around the globe of a single strain of strep known as the invasive M1T1 clone. view more (2007-07-16)
Ewing's sarcoma : Discovery of a "link" in tumor growth
To develop new therapeutic approaches to cancer, it is essential to understand the long and extremely complex process that underlies it, in other words the various stages of cancer development from the initial mutation to the tumor. Having already identified the alteration that leads to Ewing's sarcoma, a bone cancer which afflicts young people,... view more... (2004-09-23)
Genetic testing for breast cancer could benefit minorities but is underused
Ten years after the identification of the first breast cancer susceptibility genes so few high-risk minority women have received genetic counseling or testing that the standard methods of calculating risk have not been validated in these groups and the results of genetic testing can still produce surprises. view more (2005-10-19)
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