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Scripps/UC San Diego Scientists Solve Genome of Marine Organism Producing Promising Disease-Fighting Agents
Scientists at UC San Diego's Scripps Institution of Oceanography and Skaggs School of Pharmacy and Pharmaceutical Sciences have solved the genomic puzzle of an organism discovered in the oceans with potential for producing compounds showing promise in treating diseases such as cancer.   view more (2007-06-14)

No-entry zones for AIDS virus
The AIDS virus inserts its genetic material into the genome of the infected cell. Scientists of the German Cancer Research Center have now shown for the first time that the virus almost entirely spares particular sites in the human genetic material in this process. This finding may be useful for developing new, specific AIDS drugs.   view more (2009-11-13)

Single nucleotide polymorphisms and forensic genetics, maybe not such a perfect combination
Forensic genetics is the branch of genetics that, through DNA analysis and comparison, deals with the resolution of legal problems such as paternity tests. Recently, it has been proposed that single nucleotide polymorphisms (SNPs) could be used as a new genetic marker in the field eventually even replacing the methods/markers now employed. But in... view more... (2004-10-21)

"Sloppy Genes" Behave Like Their Neighbours: New Findings Reveal That The Regulation Of Gene Expression Is Much Less Strictly Controlled Than Was Previously Thought
The inaugural issue of Journal of Biology features groundbreaking research that challenges the traditional view of how genes are controlled. Our current understanding of gene expression, the fundamental process by which proteins are made from the instructions encoded in DNA, is that the process is tightly controlled so that the correct amount of... view more... (2002-06-13)

Establishing standard definitions for genome sequences
In 1996, researchers from major genome sequencing centers around the world convened on the island of Bermuda and defined a finished genome as a gapless sequence with a nucleotide error rate of one or less in 10,000 bases.   view more (2009-10-09)

Genome of Clostridium botulinum reveals the background to world's deadliest toxin
The genome of the organism that produces the world's most lethal toxin is revealed today. This toxin is the one real weapon in the genome of Clostridium botulinum and less than 2 kg - the weight of two bags of sugar - is enough to kill every person on the planet.   view more (2007-05-29)

Genetic on-off switches pinpointed in human genome
In another step to decipher information in the human genome, scientists have discovered the location and sequence of over 10,000 DNA regions that function as genetic on-off switches, or "promoters" in human fibroblasts.    view more (2005-07-01)

First draft of the pig: Researchers sequence swine genome
A global collaborative has produced a first draft of the genome of a domesticated pig, an achievement that will lead to insights in agriculture, medicine, conservation and evolution.   view more (2009-11-02)

ISU researchers help map first plant-parasitic nematode genome sequence
There are numerous plant-parasitic nematodes in the world, but only a handful are responsible for the largest part of an estimated $157 billion in agricultural damage globally every year. Nematodes are small worms that burrow into plant roots and feed off living cells.    view more (2008-09-05)

Copy number variation may stem from replication misstep
Genome rearrangements, resulting in variations in the numbers of copies of genes, occur when the cellular process that copies DNA during cell division stalls and then switches to a different genetic "template," said researchers at Baylor College of Medicine in Houston in a report that appears today in the journal Cell.   view more (2007-12-28)

Insignia -- A new way to identify viruses and bacteria
Now that the genome sequences of hundreds of bacteria and viruses are known, we can design tests that will rapidly detect the presence of these species based solely on their DNA.   view more (2007-05-18)

Beyond a 'speed limit' on mutations, species risk extinction
Harvard University scientists have identified a virtual "speed limit" on the rate of molecular evolution in organisms, and the magic number appears to be 6 mutations per genome per generation -- a level beyond which species run the strong risk of extinction as their genomes lose stability.   view more (2007-10-02)

Poison + water = hydrogen. New microbial genome shows how
Take a pot of scalding water, remove all the oxygen, mix in a bit of poisonous carbon monoxide, and add a pinch of hydrogen gas. It sounds like a recipe for a witch's brew. It may be, but it is also the preferred environment for a microbe known as Carboxydothermus hydrogenoformans.   view more (2005-12-05)

One species, many genomes
Faster growth, darker leaves, a different way of branching - wild varieties of the plant Arabidopsis thaliana are often substantially different from the laboratory strain of this small mustard plant, a favorite of many plant biologists.   view more (2007-07-23)

BGSU undergraduates to pilot groundbreaking genome project
Bowling Green State University biology undergraduates will soon be contributing to the body of knowledge in genomics while they learn. The University has been selected as one of 12 institutions nationwide to pilot the new Microbial Genome Annotation research program through the U.S. Department of Energy Joint Genome Institute (DOE JGI).   view more (2007-12-13)

Evidence that up to 10 percent of human genome may have changed very recently revealed by CU researchers
A Cornell study of genome sequences in African-Americans, European-Americans and Chinese suggests that natural selection has caused as much as 10 percent of the human genome to change in some populations in the last 15,000 to 100,000 years, when people began migrating from Africa.   view more (2007-07-12)

Mutant sperm guide clinicians to new diseases
Research published today in Nature Genetics shows that some rearrangements of the human genome occur more frequently than previously thought.   view more (2007-12-03)

University of Iowa scientists explore function of 'junk DNA'
University of Iowa scientists have made a discovery that broadens understanding of a rapidly developing area of biology known as functional genomics and sheds more light on the mysterious, so-called "junk DNA" that makes up the majority of the human genome.   view more (2006-11-14)

HIV inserts into human genome using a DNA-associated protein
A human DNA-associated protein called LEDGF is the first such molecule found to control the location of HIV integration in human cells.   view more (2005-11-28)

New genetic study sheds light on serious childhood disease
Genetic variations that can predispose children to a serious disease that damages the heart have been identified in a genome-wide association study of Kawasaki Disease, published today in PLoS Genetics.   view more (2009-01-09)
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