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Genome of Clostridium botulinum reveals the background to world's deadliest toxin
The genome of the organism that produces the world's most lethal toxin is revealed today. This toxin is the one real weapon in the genome of Clostridium botulinum and less than 2 kg - the weight of two bags of sugar - is enough to kill every person on the planet. view more (2007-05-29)
Massive reanalysis of genome data solves case of the lethal genes
It is better to be looked over than overlooked, Mae West supposedly said. These are words of wisdom for genome data-miners of today. view more (2007-10-19)
Latest Integrated Microbial Genomes (IMG) Data Management System Update Release
Version 2.4 of the Integrated Microbial Genomes (IMG) data management system, a resource provided to the scientific community for microbial genome data analysis, has now been released. view more (2007-12-06)
Scientists Find a Fingerprint of Evolution Across the Human Genome
The Human Genome Project revealed that only a small fraction of the 3 billion "letter" DNA code actually instructs cells to manufacture proteins, the workhorses of most life processes. This has raised the question of what the remaining part of the human genome does. How much of the rest performs other biological functions, and how much... view more... (2008-04-09)
Cold Spring Harbor Scientists Devise Novel, Low-Cost Method of Sifting Genome's High-Value Regions
Scientists at Cold Spring Harbor Laboratory (CSHL) have developed a new means of extracting and interpreting data from the human genome that is more powerful and more economical than methods currently employed. view more (2007-11-07)
Decoded sea urchin genome shows surprising relationship to humans
The Sea Urchin Genome Sequencing Project (SUGSP) Consortium, led by the Human Genome Sequencing Center at Baylor College of Medicine (BCM-HGSC) in Houston, announced today the decoding and analysis of the genome sequence of the sea urchin, Strongylocentrotus purpuratus. view more (2006-11-10)
Viruses Evolve To Play By Host Rules, According to University of Pennsylvania Researchers
Biologists at the University of Pennsylvania and Harvard University have examined the complete genomes of viruses that infect the bacteria E. coli, P. aeruginosa and L. lactis and have found that many of these viral genomes exhibit codon bias, the tendency to preferentially encode a protein with a particular spelling. view more (2008-03-04)
Genome fully mapped for potential biological weapon
The bacterium that causes the severe disease known as rabbit fever, Fancisella tularensis, is a potential biological weapon of devastating force. Now scientists at Ume'å, in collaboration with several international associates, have mapped the entire genome of the bacterium. Researchers at the Swedish Defense Research Agency FOI NBC Defense... view more... (2005-01-12)
Gene enhancer in evolution of human opposable thumb
Scientists have discovered a gene enhancer, known as HACNS1, that may have contributed to the evolution of the uniquely opposable human thumb, and possibly also modifications in the ankle or foot that allow humans to walk on two legs. view more (2008-09-05)
Genome of saltwater creature could aid understanding of gene grouping
The genetic code of a simple saltwater creature could help researchers learn more about how groups of genes function in humans and other species. view more (2008-08-21)
Dengue Virus Reveals Its Circular Secret
The first step in the transmission of mosquito-borne viruses is no mystery: it's the pesky insect's bite that allows the virus to enter its victim's bloodstream. But for some of the most dangerous insect-borne viruses, details of what happens next have been unclear. view more (2006-08-02)
Faster, cheaper way to find disease genes in human genome passes initial test
University of Washington (UW) researchers have successfully developed a novel genome-analysis strategy for more rapid, lower cost discovery of possible gene-disease links. view more (2009-08-18)
UCSD Study Shows Junk DNA Has Evolutionary Importance
Genetic material derisively called "junk" DNA because it does not contain the instructions for protein-coding genes and appears to have little or no function is actually critically important to an organism's evolutionary survival, according to a study conducted by a biologist at UCSD. view more (2005-10-20)
UVa-led team uncovers important secret in gene replication
A team of researchers led by University of Virginia Health System geneticists has uncovered a major secret in the mystery of how the DNA helix replicates itself time after time. view more (2007-06-14)
Genomics and world peace
Developing countries stand to profit most from advances in genome science, write Samuel Broder, Stephen Hoffman and Peter Hotez in this month`s issue of EMBO reports (EMBO reports September, 2002 pp 806-812). They claim that biotechnology coupled with genomics might emerge as the key technology in the 21st century for improving global health and... view more... (2002-08-29)
Next gen sequencing technology pinpoint 'on-off switches' in genomes
Scientists from the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), Lawrence Berkeley National Laboratory, and the University of California, San Diego have developed a set of molecular tools that provide important insight into the complex genomes of multicellular organisms. view more (2009-02-13)
Free shopping in a virtual bazaar of gene regulation data
An international team has opened a virtual bazaar, called PAZAR, which allows biologists to share information about gene regulation through individually managed 'boutiques' (data collections). view more (2007-10-04)
Rewrite the textbooks: Transcription is bidirectional
Genes that contain instructions for making proteins make up less than 2% of the human genome. Yet, for unknown reasons, most of our genome is transcribed into RNA. view more (2009-01-26)
NEW SERIES ON PRE-ECLAMPSIA (p 53)
This week's issue of THE LANCET features the first in a series of three articles about pre-eclampsia - the serious condition occuring in pregnant women characterised by high blood pressure which puts both mother and child at risk of illness and/or death. If all cases of pre-eclampsia and its complications could be predicted, prevented, and... view more... (2001-01-03)
New method enables gene disruption in destructive fungal pathogen
Researchers at the Virginia Bioinformatics Institute (VBI) at Virginia Tech, Colorado State University, and Duke University Medical Center have developed a new method to determine gene function on a genome-wide scale in the fungal pathogen Alternaria brassicicola. view more (2006-02-03)
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