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Lactose malabsorption related to bone fractures in old age?
Finnish researchers have discovered an interesting link between lactose malabsorption and the occurrence of bone fracture in elderly people.   view more (2005-02-16)

Specific Genotype Could Increase Resistance To HIV Drug Therapy (p 383)
A specific mutation of a gene which influences the expression of a glycoprotein transporter protein involved in the body's resistance to drugs and other toxins is detailed in a research letter in this week's issue of THE LANCET. Results of the study suggest that drug therapies used in treating... view more (2001-08-01)

Alcohol consumption and polymorphisms of cytochromes P4502E1 are high risks for ESCC
Heavier alcohol consumption increases the risk of ESCC. There are synergetic interactions among alcohol drinking and ALDH2, ADH1B, CYP2E1 genotypes.   view more (2008-03-13)

Researchers challenge previous findings regarding widely used asthma treatment
A new study published recently in The Lancet reveals that one of the most commonly used asthma medicines -- long-acting beta-agonists -- may not be associated with adverse events in people based on their genotype (gene variation), as previous studies had shown.   view more (2008-01-11)

How to increase the chances of remaining virus free Pakistani patients with HCV?
Hepatitis C is a health care problem all over the world, with 130 million patients infected the world over. The treatment is expensive and has variable results according to the genotype of the infecting virus.   view more (2008-05-21)

Environmental effects on genetic adaptation and population dynamics
It seems intuitive that genes are affected by selection as a result of environment. In fact there is little evidence thus far that such genetic effects impact year-to-year population dynamics.   view more (2006-04-25)

Gene mutations - possible link to meningitis
Gene mutations may account for a third of all meningococcal meningitis in the UK scientists heard today (Thursday 19 September) at the Society for General Microbiology autumn meeting at Loughborough University. "We have used family studies to calculate that differences in a person`s genetics... view more (2002-08-28)

Anti-HBe may play a role in the progression of the disease of hepatitis B
Genotype D is found to be the only detected type in different clinical forms of HBV infections, including cirrhosis, among residents of southwestern Iran. A significant association between the presence of anti-HBe antibody and increasing ALT levels among either HBeAg-negative or HBeAg-positive... view more (2008-04-30)

Article analyzes relationship of apolipoprotein E genotypes with lipid levels and coronary risk
An analysis of previously published studies suggests that there are approximately linear relationships of apolipoprotein E genotypes with lipid levels and with coronary risk   view more (2007-09-19)

UT Southwestern researchers refocus studies on patients with HIV, hepatitis
As HIV patients live longer thanks to advanced therapies, researchers are looking for better ways to treat accompanying maladies such as hepatitis that traditionally were not emphasized.   view more (2006-10-12)

Dietary preferences and patterns may be linked to genes
The relative amount of protein, carbohydrate, and fat that people choose to eat may be influenced by genetics, according to new research.   view more (2007-06-08)

Prevention of scrapie by means of selection in animals
To help prevent scrapie in sheep by means of animal selection is the aim of a project, throughout the whole of Spain, by a research group from the Agrarian Production Department of the Public University of Navarre together with other institutions such as the National Institute for Agrarian and... view more (2003-03-27)

Gene may inhibit smokers from quitting
Smokers with a particular genetic make-up (genotype) may find it harder to give up their habit, suggest Japanese researchers in Thorax. The presence of a CYP2A6del allele, a specific form of the gene involved in processing nicotine in the body, may inhibit smokers from quitting, but it also seems... view more (2003-06-27)

HepCgen genotyping service helps fight Hepatitis C, a 'silent epidemic'
Southampton UK, July 22, 2003 Genotyping provides route to tailored treatment at lower cost with less side effects A new centralised genotyping service that enables clinicians to differentiate between types of hepatitis C infections is poised to improve treatment for patients with Hepatitis C, a... view more (2003-07-22)

Genes may make some people more motivated to eat, perhaps overeat
Science has found one likely contributor to the way that some folks eat to live and others live to eat. Researchers at the University at Buffalo, The State University of New York, have found that people with genetically lower dopamine, a neurotransmitter that helps make behaviors and substances... view more (2007-10-15)

A single gene makes the chicken a victim
Feather pecking is a common and serious behavioural disorder in laying hens around the world. The chickens peck and pull the feathers of their victims, and this may lead to cannibalism. Now a group of researchers under the lead of Per Jensen, Professor of ethology at Linköping University have... view more (2004-10-04)

Metabolic disorder not well-suited for inclusion in newborn screening programs
A metabolic disorder that can lead to developmental delay and other problems is more common than previously assumed, but does not meet major criteria for inclusion in newborn screening programs at this time.   view more (2006-08-23)

For children with sickle cell disease, lung disease is part of the package
Children with sickle cell disease (SCD) have a significantly sharper decline in lung function with age when compared to other children of the same race and age.   view more (2008-05-19)

Nature, nurture and the risk of depression
Some people are more than twice as likely to become depressed as others, given similar circumstances, according to landmark research from Brain Sciences UNSW (University of New South Wales).   view more (2006-03-01)

Gene variants linked with increased risk of death among heart patients treated with beta-blockers
Patients with certain gene variants who were prescribed beta-blocker drugs after acute coronary syndrome (ACS) had an increased risk of death over the next three years, according to a study in the September 28 issue of JAMA.   view more (2005-09-28)

HORIZONTAL GENE TRANSFER COULD RESULT IN EMERGENCE OF METICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (p 1674)
A baby who developed meticillin-resistant staphylococcus aureus (MRSA) infection without exposure to MRSA carriers suggests an alternative model for the acquisition of this virulent staphylococcal infection. In a research letter in this week's issue of THE LANCET, the authors conclude that a new... view more (2001-05-23)

Transmission of tuberculosis is linked to historical patterns of human migration
In this study, a team of scientists led by Dr. Igor Mokrousov from St. Petersburg's Pasteur Institute demonstrated that the evolutionary history of the causative agent of tuberculosis (TB) has been shaped by human migration patterns.   view more (2005-09-27)

Mutation of the COX2 gene can double or treble a woman's risk of ovarian cancer
Researchers in Portugal have discovered that a specific mutation of the COX2 gene seems to play a role in the onset of ovarian cancer, increasing women's susceptibility to developing the disease.   view more (2007-09-26)

Common genetic variants linked with progression to advanced forms of AMD
Variations of two common genes are associated with progression to more advanced forms of age-related macular degeneration, and factors such as smoking and being overweight greatly increase this risk.   view more (2007-04-25)

Who will recover spontaneously from hepatitis C virus infection
More than 3% of world population is infected with hepatitis C virus (HCV). The outcome of HCV infections is either self recovery or chronic hepatitis, and many of the chronic infections will develop into liver cirrhosis or liver cancer.   view more (2007-08-30)
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