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Salk researchers develop novel glioblastoma mouse model
Researchers at the Salk Institute for Biological Studies have developed a versatile mouse model of glioblastoma-the most common and deadly brain cancer in humans-that closely resembles the development and progression of human brain tumors that arise naturally.   view more (2009-01-05)

Combined radiation seed, chemotherapy wafer implants show promise in treating cancerous brain tumors
In the battle against malignant brain tumors, dual implantation of radioactive seeds and chemotherapy wafers following surgery showed promising results in a study led by specialists at the Neuroscience Institute at the University of Cincinnati (UC) and University Hospital.   view more (2008-01-18)

Stealthy gene network makes brain tumors flourish
The brain tumor afflicting Sen. Edward Kennedy - a glioblastoma - is the most aggressive and wily form of brain cancer.   view more (2009-07-15)

Drugs to inhibit blood vessel growth show promise in rat model of deadly brain tumor
In a landmark study, Medical College of Wisconsin researchers in Milwaukee report that drugs used to inhibit a specific fatty acid in rat brains with glioblastoma-like tumors not only reduced new blood vessel growth and tumor size dramatically, but also prolonged survival. The study is the featured cover story of the August, 2008 Journal of... view more... (2008-08-22)

New approach to gene therapy may shrink brain tumors, prevent their spread
Massachusetts General Hospital (MGH) researchers are investigating a new approach to gene therapy for brain tumors - delivering a cancer-fighting gene to normal brain tissue around the tumor to keep it from spreading.   view more (2008-09-26)

Angiochem crosses BBB, shows safety, efficacy in phase 1/2 brain cancer studies
Angiochem, Inc. a clinical-stage biotechnology company developing drugs that are uniquely capable of crossing the blood-brain barrier to treat brain diseases, announced today that its lead drug candidate, ANG1005, has demonstrated a favorable safety and efficacy profile in more than 100 patients with brain cancer from two separate Phase 1 /2... view more... (2009-10-19)

Angiogenesis inhibitor improves brain tumor survival by reducing edema
The beneficial effects of anti-angiogenesis drugs in the treatment of the deadly brain tumors called glioblastomas appear to result primarily from reduction of edema - the swelling of brain tissue - and not from any direct anti-tumor effect.   view more (2009-03-30)

Radiotherapy advance points way to noninvasive brain cancer treatment
With an equal rate of incidence and mortality-the number of those who get it, and the number of those who die from it-Glioblastoma Multiforme (GBM) is a brain cancer death sentence.   view more (2006-01-03)

Researchers identify target for therapeutic drugs to fight most common adult brain cancer
A research team at UT Southwestern Medical Center has discovered a cell-signaling mechanism instrumental in the most common brain cancer in adults.   view more (2006-01-16)

Cedars-Sinai researchers discover treatment for deadly brain tumors and infections
In a study published in the March 15 issue of The Journal of Immunology, researchers at Board of Governors' Gene Therapeutics Research Institute at Cedars-Sinai Medical Center have developed a way to overcome immune privilege in the brain to eradicate potentially deadly brain tumors such as glioblastoma multiforme and other types of brain... view more... (2006-03-27)

Biomarkers predict brain tumor's response to therapy
A report in Cancer Research, a journal of the American Association for Cancer Research, highlights a new biomarker that may be useful in identifying patients with recurrent glioblastoma, or brain tumors, who would respond better to anti-vascular endothelial growth factor therapy, specifically cediranib.   view more (2009-06-24)

Cancer stem cells linked to radiation resistance
Certain types of brain cancer cells, called cancer stem cells, help brain tumors to buffer themselves against radiation treatment by activating a "repair switch" that enables them to continue to grow unchecked.   view more (2006-10-19)

Anti-psychotic drugs could help fight cancer
The observation that people taking medication for schizophrenia have lower cancer rates than other people has prompted new research revealing that anti-psychotic drugs could help treat some major cancers.   view more (2009-08-12)

Cancer-killing viruses influence tumor blood-vessel growth
Viruses genetically designed to kill cancer cells offer a promising strategy for treating incurable brain tumors such as glioblastoma, but the body's natural defenses often eliminate the viruses before they can eliminate the tumor.   view more (2008-06-11)

Sensitizing tumor response to cancer therapy
Two forms of skin and brain cancer respond very poorly to chemotherapy and radiation: melanoma and glioblastoma multiforme brain cancer.   view more (2009-08-06)

Hopkins geneticist discovers mutations in cancer cells that suggest new forms of treatment
Researchers at Johns Hopkins have identified three new genetic mutations in brain tumors, a discovery that could pave the way for more effective cancer treatments.   view more (2005-09-27)

Why don't brain tumors respond to medication?
Malignant brain tumors often fail to respond to promising new medication. Researchers in Heidelberg have discovered a mechanism and a tumor marker for the development of this resistance.   view more (2009-09-01)

A crystal ball for brain cancer?
UCLA researchers have uncovered a new way to scan brain tumors and predict which ones will be shrunk by the drug Avastin -- before the patient ever starts treatment.   view more (2009-07-30)

Toward a nanomedicine for brain cancer
In an advance toward better treatments for the most serious form of brain cancer, scientists in Illinois are reporting development of the first nanoparticles that seek out and destroy brain cancer cells without damaging nearby healthy cells.   view more (2009-09-10)

New imaging technique tracks cancer-killing cells over prolonged period
Coaxing a patient's own cells to hunt down and tackle infected or diseased cells is a promising therapeutic approach for many disorders.   view more (2008-11-18)
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