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Inhaled asthma drugs more effective than oral therapy
Inhaled glucocorticoid drugs are more effective than the newer anti-leukotriene tablets for adults with mild or moderate asthma, concludes a study in this week’s BMJ.   view more (2003-03-19)

Prenatal exposure to glucocorticoids has long-term deleterious effects on newborns
Researchers at the University of Edinburgh in the United Kingdom have found that, as for rodents and other nonprimates, prenatal exposure of nonhuman primate African vervet monkeys (Chloroceus aethiops) to glucocorticoids has long-lasting deleterious effects on cardiovascular, metabolic, and... view more (2007-03-23)

Link found between steroid anti-inflammatories and heart disease
Results of a population study in Scotland will reveal today at the British Endocrine Societies 2003 meeting that patients taking anti-inflammatory steroid drugs are at a greater risk of heart disease. Taking high doses of glucocorticoids, commonly prescribed to alleviate conditions including... view more (2003-03-19)

Steroid use fails to boost pregnancy rates in infertility treatments
There is no clear benefit from a hormone commonly prescribed to enhance the effectiveness of infertility treatments, according to a new review of studies.   view more (2007-03-02)

Blood pressure drug curbs brain damage from PTSD
A drug used to treat high blood pressure and enlargement of the prostate may protect the brain from damage caused by post-traumatic stress disorder, Alzheimer's disease, depression and schizophrenia.   view more (2007-11-07)

Breathe deep: Which patients could benefit from inhaled steroids in cystic fibrosis?
A specific variation in the glucocorticoid receptor gene is associated with lung disease progression in cystic fibrosis, research published this week in the online open access journal Respiratory Research reveals.   view more (2007-11-29)

Small protein may have big role in making more bone and less fat
A small protein may have a big role in helping you make more bone and less fat, researchers say.   view more (2008-07-02)

Researchers reveal how long-term use of anti-inflammatory medication can cause osteoporosis
The steroid hormones glucocorticoids (GCs) are used at high doses to treat inflammatory and immune disorders, however they prompt bone loss and can cause osteoporosis, particularly when administered for prolonged periods.   view more (2006-07-28)

New hope for HIV sufferers as immunosuppressant delays AIDS onset
A drug that suppresses the immune system delays the onset of AIDS in patients with HIV, according to a study published this week in BMC Medicine. Prednisolone, taken without any antiviral therapy, postponed the loss of T-cells that leads to AIDS in 50% of HIV sufferers by between 2 and 10 years.... view more (2004-04-30)

Glucocorticoid plays key role in skin abnormalities induced by psychological stress
Inhibiting glucocorticoid, a type of steroid, can prevent skin abnormalities induced by psychological stress, according to a new study from the December issue of the American Journal of Physiology-Regulatory, Integrative and Comparative Physiology.   view more (2006-12-01)

EDINBURGH MEN SOUGHT FOR MEMORY LOSS STUDY
Professor Jonathan Seckl's team, based at the Centre for the Study of the Ageing Brain at the Western General Hospital, has already carried out research which indicates memory loss in the elderly may tie in with higher-than-normal levels of glucocorticoids, hormones which boost blood sugar levels... view more (1999-06-21)

Researchers find docking sites for glucocorticoid receptor and Hsp90
University of Oregon researchers have identified protein interactions that regulate the response of cells to steroid hormones. The discovery, they say, could lead to new ways to boost the effectiveness and reduce undesired side effects of steroid-hormone treatments and cancer drugs.   view more (2006-11-21)

Steroids Not as Effective in Obese Asthma Patients
Researchers at National Jewish Health have shown that glucocorticoids, the primary controller medication for asthma, are 40 percent less effective in overweight and obese asthma patients than in those of normal weight.   view more (2008-09-17)

Research with squirrels provides clues on hormone's role in human learning
Tests on the influence that a stress-related hormone has on learning in ground squirrels could have an impact on understanding how it influences human learning, according to a University of Chicago researcher.   view more (2008-03-14)

Light-induced hormone surge points to benefits of light therapy
A report in the November Cell Metabolism reveals powerful effects of light on the adrenal glands, a finding that might explain the broad benefits of bright light therapy for a variety of conditions, including sleep and depressive disorders, according to researchers.   view more (2005-11-09)

A possible mechanistic link between stress and the development of Alzheimer tangles
Subjecting mice to repeated emotional stress, the kind we experience in everyday life, may contribute to the accumulation of neurofibrillary tangles, one of the hallmarks of Alzheimer's disease, report researchers at the Salk Institute for Biological Studies.   view more (2007-06-18)

Foetal programming of adult high blood pressure
New results, presented today at the British Endocrine Societies 2003 meeting, from a study by a group at the Western General Hospital in Edinburgh may explain why foetal exposure to high levels of the stress hormone, cortisol (a glucocorticoid), is linked to high blood pressure in adults. The... view more (2003-03-19)

Scientists use gene signatures to match cancer and other diseases with potentially effective drugs
In one of the most ambitious spinoffs of the human genome project, researchers at Dana-Farber Cancer Institute, Children's Hospital Boston, the Broad Institute of Harvard and MIT, and other collaborating centers have unveiled a new, systematic approach to drug discovery that matches diseases with... view more (2006-09-29)

Scientists use gene therapy to improve memory and learning in animals
Stanford University neuroscientists have designed a gene that enhances memory and learning ability in animals under stress.   view more (2006-11-08)

Arthritis medications reduce the risk of heart attacks and strokes
Patients prescribed drugs to treat rheumatoid arthritis could be at a reduced risk of heart attacks and strokes, according to a study published today in the open access journal Arthritis Research & Therapy.   view more (2008-03-06)

Against pulmonary fibrosis
The biotech companies Digna Biotech and Biotherapix have signed an agreement to jointly apply their patented products towards the development of a treatment for pulmonary fibrosis.   view more (2006-03-06)

New study replicates association between genetic variation and antidepressant treatment response
Pharmacogenetics, the study of genetic variation that influences an individual's response to drugs, is an important and growing focus in all of medical research, including psychiatry.   view more (2008-07-16)

Keeping the body in sync — The stability of cellular clocks
A study in Switzerland uses the tools of physics to show how our circadian clocks manage to keep accurate time in the noisy cellular environment.   view more (2007-03-13)

Baboons in Mourning Seek Comfort Among Friend
When Sylvia the baboon lost Sierra, her closest grooming partner and daughter, to a lion, she responded in a way that would be considered very human-like: she looked to friends for support.   view more (2006-01-31)

Steroid medications don't work in treating lower respiratory infections in children
The use of steroid medication to treat bronchiolitis - a common viral lower respiratory infection in infants - does not prevent hospitalization or improve their respiratory symptoms.   view more (2007-07-26)
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