Glucocorticoids Current Events | Glucocorticoids News
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Inhaled asthma drugs more effective than oral therapy
Inhaled glucocorticoid drugs are more effective than the newer anti-leukotriene tablets for adults with mild or moderate asthma, concludes a study in this week’s BMJ. view more (2003-03-19)
Prenatal exposure to glucocorticoids has long-term deleterious effects on newborns
Researchers at the University of Edinburgh in the United Kingdom have found that, as for rodents and other nonprimates, prenatal exposure of nonhuman primate African vervet monkeys (Chloroceus aethiops) to glucocorticoids has long-lasting deleterious effects on cardiovascular, metabolic, and neuroendocrine function. view more (2007-03-23)
Link found between steroid anti-inflammatories and heart disease
Results of a population study in Scotland will reveal today at the British Endocrine Societies 2003 meeting that patients taking anti-inflammatory steroid drugs are at a greater risk of heart disease. Taking high doses of glucocorticoids, commonly prescribed to alleviate conditions including asthma, rheumatoid arthritis and inflammatory bowel... view more... (2003-03-19)
Steroid use fails to boost pregnancy rates in infertility treatments
There is no clear benefit from a hormone commonly prescribed to enhance the effectiveness of infertility treatments, according to a new review of studies. view more (2007-03-02)
Blood pressure drug curbs brain damage from PTSD
A drug used to treat high blood pressure and enlargement of the prostate may protect the brain from damage caused by post-traumatic stress disorder, Alzheimer's disease, depression and schizophrenia. view more (2007-11-07)
Breathe deep: Which patients could benefit from inhaled steroids in cystic fibrosis?
A specific variation in the glucocorticoid receptor gene is associated with lung disease progression in cystic fibrosis, research published this week in the online open access journal Respiratory Research reveals. view more (2007-11-29)
Researchers reveal how long-term use of anti-inflammatory medication can cause osteoporosis
The steroid hormones glucocorticoids (GCs) are used at high doses to treat inflammatory and immune disorders, however they prompt bone loss and can cause osteoporosis, particularly when administered for prolonged periods. view more (2006-07-28)
Small protein may have big role in making more bone and less fat
A small protein may have a big role in helping you make more bone and less fat, researchers say. view more (2008-07-02)
NIH prepares to launch 2009 H1N1 influenza vaccine trial in people with asthma
The National Institutes of Health is preparing to launch the first government-sponsored clinical trial to determine what dose of the 2009 H1N1 influenza vaccine is needed to induce a protective immune response in people with asthma, especially those with severe disease. view more (2009-10-12)
New hope for HIV sufferers as immunosuppressant delays AIDS onset
A drug that suppresses the immune system delays the onset of AIDS in patients with HIV, according to a study published this week in BMC Medicine. Prednisolone, taken without any antiviral therapy, postponed the loss of T-cells that leads to AIDS in 50% of HIV sufferers by between 2 and 10 years. HIV leads to a complex disorder that combines an... view more... (2004-04-30)
Glucocorticoid plays key role in skin abnormalities induced by psychological stress
Inhibiting glucocorticoid, a type of steroid, can prevent skin abnormalities induced by psychological stress, according to a new study from the December issue of the American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. view more (2006-12-01)
EDINBURGH MEN SOUGHT FOR MEMORY LOSS STUDY
Professor Jonathan Seckl's team, based at the Centre for the Study of the Ageing Brain at the Western General Hospital, has already carried out research which indicates memory loss in the elderly may tie in with higher-than-normal levels of glucocorticoids, hormones which boost blood sugar levels in times of stress. The researchers believe... view more... (1999-06-21)
Researchers find docking sites for glucocorticoid receptor and Hsp90
University of Oregon researchers have identified protein interactions that regulate the response of cells to steroid hormones. The discovery, they say, could lead to new ways to boost the effectiveness and reduce undesired side effects of steroid-hormone treatments and cancer drugs. view more (2006-11-21)
Stress puts double whammy on reproductive system, fertility
University of California, Berkeley, researchers have found what they think is a critical and, until now, missing piece of the puzzle about how stress causes sexual dysfunction and infertility. view more (2009-06-16)
Steroids Not as Effective in Obese Asthma Patients
Researchers at National Jewish Health have shown that glucocorticoids, the primary controller medication for asthma, are 40 percent less effective in overweight and obese asthma patients than in those of normal weight. view more (2008-09-17)
Research with squirrels provides clues on hormone's role in human learning
Tests on the influence that a stress-related hormone has on learning in ground squirrels could have an impact on understanding how it influences human learning, according to a University of Chicago researcher. view more (2008-03-14)
Light-induced hormone surge points to benefits of light therapy
A report in the November Cell Metabolism reveals powerful effects of light on the adrenal glands, a finding that might explain the broad benefits of bright light therapy for a variety of conditions, including sleep and depressive disorders, according to researchers. view more (2005-11-09)
A possible mechanistic link between stress and the development of Alzheimer tangles
Subjecting mice to repeated emotional stress, the kind we experience in everyday life, may contribute to the accumulation of neurofibrillary tangles, one of the hallmarks of Alzheimer's disease, report researchers at the Salk Institute for Biological Studies. view more (2007-06-18)
Foetal programming of adult high blood pressure
New results, presented today at the British Endocrine Societies 2003 meeting, from a study by a group at the Western General Hospital in Edinburgh may explain why foetal exposure to high levels of the stress hormone, cortisol (a glucocorticoid), is linked to high blood pressure in adults. The study showed that prenatal exposure to glucocorticoids... view more... (2003-03-19)
Scientists use gene signatures to match cancer and other diseases with potentially effective drugs
In one of the most ambitious spinoffs of the human genome project, researchers at Dana-Farber Cancer Institute, Children's Hospital Boston, the Broad Institute of Harvard and MIT, and other collaborating centers have unveiled a new, systematic approach to drug discovery that matches diseases with potential treatments using a universal language... view more... (2006-09-29)
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