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The glutamate decarboxylase 1 gene may play a pivotal role in developing alcoholism
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the brain. GABA has been implicated in the development of alcoholism, although the mechanisms through which this occurs are unclear. view more (2006-10-25)
Disruption of gene interaction linked to schizophrenia
Disruption of the normal interaction between the genes PRODH and COMT contributes directly to major symptoms of schizophrenia by upsetting the balance of the brain chemicals glutamate and dopamine. view more (2005-12-02)
Fragile X retardation syndrome corrected in mice
Researchers working with mice have significantly alleviated a wide range of abnormalities due to fragile X syndrome by altering only a single gene, countering the effects of the fragile X mutation. view more (2007-12-20)
Short Stressful Events May Improve Working Memory
Experiencing chronic stress day after day can produce wear and tear on the body physically and mentally, and can have a detrimental effect on learning and emotion. However, acute stress -- a short stressful incident -- may enhance learning and memory. view more (2009-07-24)
Scientists show how thinking can harm brain cells
Scientists at the University of Rochester Medical Center have targeted a new culprit and method of attack on neurologic functions in diseases such as Alzheimer's and dementia associated with HIV. view more (2005-11-04)
Uric acid and spinal cord injury treatment
Uric acid is commonly associated with the excruciatingly painful joint disease known as gout, but it can also play a crucial role in the treatment of spinal cord injury and other central nervous system disorders, such as stroke, multiple sclerosis and Parkinson's disease, according to Rutgers' Bonnie Firestein. view more (2007-01-04)
Faster-acting antidepressants closer to becoming a reality
A new study has revealed more about how the medication ketamine, when used experimentally for depression, relieves symptoms of the disorder in hours instead of the weeks or months it takes for current antidepressants to work. view more (2007-07-25)
How brain injury leads to seizures, memory problems
In a finding that may provide a scientific basis for eventual treatment, neurology researchers have shown that traumatic brain injury reduces the level of a protein that helps keep brain activity in balance. view more (2006-10-19)
A new mouse model of mania
Bipolar Disorder (BPD or manic-depressive illness) is one of the most serious of all mental disorders, affecting millions of individuals worldwide. view more (2008-03-12)
Scientists find how neural activity spurs blood flow in the brain
New research from Harvard University neuroscientists has pinpointed exactly how neural activity boosts blood flow to the brain. The finding has important implications for our understanding of common brain imaging techniques such as fMRI, which uses blood flow in the brain as a proxy for neural activity. view more (2008-06-26)
CSHL team solves structure of NMDA receptor unit that could be drug target for neurological diseases
A team of scientists at Cold Spring Harbor Laboratory (CSHL) reports on Thursday their success in solving the molecular structure of a key portion of a cellular receptor implicated in Alzheimer's, Parkinson's, and other serious illnesses. view more (2009-11-12)
Mutation in brain cells of descendants of Abraham Lincoln suggest he suffered from movement disorder
Researchers at Johns Hopkins and the University of Minnesota have discovered a gene mutation in the descendants of Abraham Lincoln's grandparents that suggests the Civil War president himself might have also suffered from a disease that destroys nerve cells in the cerebellum- the part of the brain that controls movement. view more (2006-02-03)
Brain study may lead to improved epilepsy treatments
Using a rodent model of epilepsy, researchers found one of the body's own neurotransmitters released during seizures, glutamate, turns on a signaling pathway in the brain that increases production of a protein that could reduce medication entry into the brain. view more (2008-04-15)
Amino acid may help treat patients with hair-pulling condition
The amino acid N-acetylcysteine appears to reduce symptoms of compulsive hair-pulling in patients with a condition known as trichotillomania. view more (2009-07-07)
Life and death in the hippocampus: what young neurons need to survive
Whether newborn nerve cells in adult brains live or die depends on whether they can muscle their way into networks occupied by mature neurons. view more (2006-08-14)
Chemical signature of manic depression discovered by scientists
People with manic depression have a distinct chemical signature in their brains, according to a new study. The research, published today in the journal Molecular Psychiatry, may also indicate how the mood stabilisers used to treat the disorder counteract the changes in the brain that it appears to cause. view more (2008-02-06)
Important New Research Identifies How Brain Cells Die During A Stroke
Medical Research Council (MRC) scientists, in collaboration with colleagues from British and Italian universities, have unveiled a mechanism that causes the death of brain cells (neurons) in stroke. The discovery may help explain why some therapy approaches for stroke have been unsuccessful and identifies potential research avenues for the... view more... (2005-01-25)
Now hear this
Deep in the ear, 95 percent of the cells that shuttle sound to the brain are big, boisterous neurons that, to date, have explained most of what scientists know about how hearing works. view more (2009-10-23)
ADHD genes found, known to play roles in neurodevelopment
Pediatric researchers have identified hundreds of gene variations that occur more frequently in children with attention-deficit hyperactivity disorder (ADHD) than in children without ADHD. view more (2009-06-24)
Reward-stress link points to new targets for treating addiction
Rewarding and stressful signals don't seem to have much in common. But researchers studying diseases ranging from drug addiction to anxiety disorders are finding that the brain's reward and stress signaling circuits are intertwined in complex ways. view more (2008-12-17)
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