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Abnormal glutamine repeats interfere with key transcription factor, leading to neurodegeneration
Although repeating sequences of three nucleotides encoding some of the bodies' 20 amino acids are a normal part of protein composition, abnormal expansion of trinucleotide repeats is the known cause of multiple inherited neurodegenerative disorders, including Huntington disease. view more (2007-11-14)
High-tech spectroscopy may be used to monitor neuropsychiatric symptoms
Magnetic resonance spectroscopy (MRS) may provide a noninvasive way to monitor neuropsychiatric symptoms in patients with lupus, according to results from research in mice at Wake Forest University School of Medicine. view more (2006-11-13)
Glutamine supplements show promise in treating stomach ulcers
Nearly 20 years ago, it was discovered that bacteria known as Helicobacter pylori were responsible for stomach ulcers. view more (2009-05-18)
Study points to molecular origin of neurodegenerative disorders, including Huntington's disease
New research from the University of North Carolina at Chapel Hill School of Medicine points to the possible molecular origin of at least nine human diseases of nervous system degeneration. view more (2005-09-26)
'Intrabody' can mop up mutant protein in Huntington's disease model
Scientists have created a tool for mopping up the clumps of mutant protein that drive neurodegeneration in Huntington's disease. Emory University researchers engineered a virus to make an intracellular antibody or "intrabody" against huntingtin, the protein whose mutant forms poison the brain cells of people with Huntington's. view more (2008-05-27)
New therapy may mean less dietary restrictions for celiac sufferers
Scientists have discovered what may be a successful non-dietary therapy for celiac sprue, an inherited inflammatory disorder of the small intestine that impacts an estimated 1 in 200 people around the world. view more (2006-06-26)
Hepatic encephalopathy and prehepatic portal hypertension rat model
A research article to be published June 21, 2009 in the World Journal of Gastroenterology addresses this question. The research team lead by Dr. Gabriela Beatriz Acosta, observed that the activity of GS was increased in the hippocampus in PH rats. view more (2009-06-29)
Discovery of Tuberculosis Bacterium Enzyme Paves Way for New TB Drugs
A team of University of Maryland scientists has paved the way for the development of new drug therapies to combat active and asymptomatic (latent) tuberculosis infections by characterizing the unique structure and mechanism of an enzyme in M. tuberculosis, the bacterium that causes the disease. Assistant Professor of Chemistry and Biochemistry... view more... (2009-03-30)
Alternatives to the use of nitrate as a fertiliser
In order to develop sustainable agricultural production, what is required is a study of nitrogenated sources as alternatives to the nitrates that predominate in agricultural soils and that have a greater contaminant capacity. view more (2006-04-19)
Solving the mystery of mutated proteins and the brain
In some neurological diseases, too much of what is usually a good thing can be bad, said researchers at Baylor College of Medicine in a report in this week's issue of the journal Cell. view more (2005-08-26)
RNA Toxicity Contributes to Neurodegenerative Disease, University of Pennsylvania Scientists Say
Expanding on prior research performed at the University of Pennsylvania, Penn biologists have determined that faulty RNA, the blueprint that creates mutated, toxic proteins, contributes to a family of neurodegenerative disorders in humans. view more (2008-05-22)
Huntington's disease problem start early
The damaging effects of the mutated protein involved in Huntington's disease take place earlier in cell life than previously believed, said researchers from Baylor College of Medicine in Houston in a report that appears in the current edition of the journal Neuron. view more (2008-01-10)
Strategies for preventing gastrointestinal complications in severely burned patients
Gastrointestinal dysfunction is a common complication of severe burns. Injury to GI function, especially to GI barrier function, is an important initiator as well as a stimulator for occurrence of systemic inflammatory response syndrome, sepsis and multiple organ dysfunction syndrome following severe burns. view more (2008-09-18)
New therapeutic strategy could target toxic protein in most patients with Huntington's disease
Howard Hughes Medical Institute researchers have designed tiny RNA molecules that shut off the gene that causes Huntington's disease without damaging that gene's healthy counterpart, which maintains the health and vitality of neurons. view more (2009-04-10)
Scientists on track for early diagnosis of neurological diseases
Possible treatments for fatal neurodegenerative diseases such as CJD, Alzheimer's, Parkinson's could result from University of Edinburgh research to find out how specific proteins cause deterioration in brain function. The scientists have discovered for the first time that protein 14-3-3 plays a key role in the development of certain brain... view more... (2003-07-01)
Researchers sequence the basal eukaryote Tetrahymena thermophila
In an effort to improve our understanding of eukaryotic evolution, a team of over 50 researchers led by Jonathan Eisen sequenced the macronuclear genome of the single-celled ciliate Tetrahymena themophila. view more (2006-08-29)
Mechanism for neurodenegerative diseases linked to transport proteins
Hampering the transport of proteins within cells may underlie several adult-onset neurodegenerative diseases, such as Huntington's, ALS and Kennedy disease. Understanding how this cell transport is blocked in these diseases may offer targets for future therapy. view more (2006-06-09)
Study suggests new treatments for Huntington's disease
Working with fruit flies, researchers have discovered a new mechanism by which the abnormal protein in Huntington's disease causes neurodegeneration. view more (2008-01-10)
Chemical signature of manic depression discovered by scientists
People with manic depression have a distinct chemical signature in their brains, according to a new study. The research, published today in the journal Molecular Psychiatry, may also indicate how the mood stabilisers used to treat the disorder counteract the changes in the brain that it appears to cause. view more (2008-02-06)
Plastic surgeons warn of malnutrition in body contouring patients
Identifying malnutrition before surgery in massive weight loss patients seeking body contouring will significantly decrease surgical complications, accelerate wound healing, improve scar quality and boost patient energy levels, according to a study in the December issue of Plastic and Reconstructive Surgery. view more (2008-11-13)
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