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Proven At Last - Alcohol Consumption Increases Increases Risk Of Gout (pp xxx, 1277)
The first large epidemiological study to assess the age-old belief that alcohol consumption increases the risk of gout is published in this week's issue of THE LANCET. A prospective study of nearly 50,000 men showed that beer drinking was more likely to be associated with gout than spirits; whereas moderate wine consumption was not linked to a... view more... (2004-04-14)
Johns Hopkins scientists out a gene for gout
Having partnered last year with an international team that surveyed the genomes of 12,000 individuals to find a genetic cause for gout, Johns Hopkins scientists now have shown that the malfunctioning gene they helped uncover can lead to high concentrations of blood urate that forms crystals in joint tissue, causing inflammation and pain - the... view more... (2009-06-19)
Investment in Parkinson's disease data bank yields potential therapy
Individuals with Parkinson's disease who have higher levels of a metabolite called urate in their blood and in cerebrospinal fluid (CSF) have a slower rate of disease progression. view more (2009-10-13)
Researchers discover that SLC2A9 is a high-capacity urate transporter in humans
An international team of researchers led by Professors Mark Caulfield and Patricia Munroe, from the William Harvey Research Institute at Barts and The London School of Medicine and Dentistry with Chris Cheeseman at the University of Alberta in Canada and Kelle Moley at the University of Washington in USA, have shown that the SLC2A9 gene, which... view more... (2008-10-07)
High levels of uric acid may be associated with high blood pressure
Reducing levels of uric acid in blood lowered blood pressure to normal in most teens in a study designed to investigate a possible link between blood pressure and the chemical, a waste product of the body's normal metabolism. view more (2008-08-27)
Uric acid and spinal cord injury treatment
Uric acid is commonly associated with the excruciatingly painful joint disease known as gout, but it can also play a crucial role in the treatment of spinal cord injury and other central nervous system disorders, such as stroke, multiple sclerosis and Parkinson's disease, according to Rutgers' Bonnie Firestein. view more (2007-01-04)
Same gene mutation in urinary protein responsible for two different types of kidney disease
The same gene mutation in a urinary protein causes two different types of kidney disease, research in the Journal of Medical Genetics shows. view more (2002-12-06)
Researchers shed light on genetic factors behind UK's biggest killer
Researchers investigating the biochemical characteristics behind several everyday diseases have discovered a new chromosomal region to be strongly associated with the bad cholesterol, low density lipoprotein, (LDL). view more (2008-01-11)
Blood urate levels associated with the progression of Parkinson's disease
Higher blood levels of the compound urate, a salt derived from uric acid that is associated with gout, may be associated with a slower progression of Parkinson's disease. view more (2008-04-15)
Improving the standard of rheumatology care in Europe
The Annual European Congress of Rheumatology commenced today with a comprehensive set of recommendations which aim to clarify treatment options for a range of debilitating rheumatic conditions. view more (2006-06-22)
At-risk drinking associated with higher death rates among men with certain diseases
Older men who drink as few as two drinks twice a week and also have diseases that could be worsened by alcohol or cause problems with medications taken while drinking alcohol have higher death rates, as compared to men who either drink less or may drink more but don't have such comorbidities. view more (2006-04-10)
Research Shows Cherry Juice May Prevent Muscle Damage Pain
The familiar "no pain, no gain" phrase usually associated with exercise may be a thing of the past if results from a study on cherry juice published today in the online version of the British Journal of Sports Medicine prove true in future research. view more (2006-06-23)
Mutation in renin gene linked to inherited kidney disease
A mutation in a gene that helps regulate high blood pressure is a cause of inherited kidney disease, according to a new study by researchers at Wake Forest University School of Medicine, Charles University in Prague and colleagues. view more (2009-08-19)
Hope for arthritis, heart attack, stroke relief found in unique 'acid active' receptor
he fact that arthritis pain and inflammation regularly comes and goes despite drug and other interventions "suggests that additional pathways can rekindle arthritic responses," according to researchers at the University of Texas Medical Branch in Galveston. view more (2005-10-24)
Killing the messenger RNA — But which one?
Tiny molecules called microRNAs, only 19 to 21 nucleotides in length, are able to effectively silence sometimes large sets of genes. They do this by specifically binding to and neutralizing another form of RNA called messenger RNA, responsible for conveying the information from genes to the cellular machinery that uses that information to create... view more... (2007-02-23)
Research identifies new link between tart cherries and risk factors for heart disease
New research continues to link tart cherries, one of today's hottest "Super Fruits," to lowering risk factors for heart disease. view more (2008-10-23)
Cherries may help reduce metabolic syndrome and heart disease risk factors
Increasing intake of antioxidant-rich cherries may help lower the risk of metabolic syndrome and cardiovascular disease, suggests a new study(1) presented today at the Experimental Biology annual meeting. view more (2007-04-30)
Study supports possible role of urate in slowing Parkinson's disease progression
By examining data from a 20-year-old clinical trial, a research team based at the MassGeneral Institute for Neurodegenerative Diseases (MGH-MIND) and Harvard School of Public Health (HSPH), has found evidence supporting the findings of their 2008 study - that elevated levels of the antioxidant urate may slow the progression of Parkinson's disease. view more (2009-10-13)
Rochester-led Parkinson's study pays off again, 2 decades later
Parkinson disease progresses more slowly in patients who have higher levels of urate, a chemical that at very high level is associated with gout, scientists have found. view more (2009-10-13)
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