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Compound has potential for new class of AIDS drugs
Researchers have developed what they believe is the first new mechanism in nearly 20 years for inhibiting a common target used to treat all HIV patients, which could eventually lead to a new class of AIDS drugs.   view more (2008-05-15)

LIPODYSTROPHY RISK FROM HIV-1 THERAPY (p 592)
The risk of lipodystrophy (abnormal fat distribution) in HIV-1 individuals undergoing antiretroviral therapy cannot be attributed to one antiretroviral agent, conclude authors of a study in this week's issue of THE LANCET. Lipodystrophy among HIV-1-infected patients receiving antiretroviral therapy... view more (2001-02-21)

PET Scans Could Provide Insight Into HIV-1 Progression (pp 945, 959)
An article and a research letter in this week's issue of THE LANCET provide preliminary data suggesting that positron emission tomography (PET) scans could identify the effect of HIV-1 infection on the body's lymphatic system. Authors of the studies suggest that activation of specific lymph nodes... view more (2003-09-17)

Study finds HIV protease inhibitor drugs may adversely affect the scaffolding of the cell nucleus
UCLA scientists, along with collaborators from Purdue University, have demonstrated that HIV protease inhibitors - crucial drugs for HIV treatment - block a cellular enzyme important for generating the structural scaffolding for the cell nucleus.   view more (2007-07-17)

Measures needed to reduce bloodborne infections in Irish prisons
There is an urgent need for increased infection control and harm reduction measures to reduce the transmission of hepatitis B and C viruses, and HIV in Irish prisons, concludes a study in this week's BMJ.   view more (2001-11-20)

Multivitamins improve birth outcomes among children born to HIV-negative women
Each year an estimated 20 million children are born with low birth weight worldwide, more than 95% of them in developing countries. Low birth weight, defined as less than 2,500 grams (5.5 pounds), is associated with increased risk of negative health outcomes, including neonatal and infant... view more (2007-04-05)

AMPATH: Restoring lives not just immune systems
he HIV/AIDS epidemic in Sub-Saharan Africa is decimating populations, depressing economies, deepening poverty and destabilizing traditional social orders.   view more (2007-11-27)

COST-EFFECTIVENESS ASSESSMENTS IMPORTANT FOR HIV RESPONSE IN AFRICA (p 1635)
A systematic review in this week's issue of THE LANCET highlights the importance of cost-effectiveness evaluation to identify realistic intervention programmes to tackle HIV/AIDS in Africa. HIV/AIDS accounts for around 20% of all deaths in Africa. The cost-effectiveness of interventions is... view more (2002-05-08)

Lifetime trauma may speed progression of HIV, early death
Even though effective drug cocktails have improved the outlook for many patients with HIV, disease progression, including the time from AIDS onset to death, varies widely from patient to patient.   view more (2007-11-02)

New hope for HIV sufferers as immunosuppressant delays AIDS onset
A drug that suppresses the immune system delays the onset of AIDS in patients with HIV, according to a study published this week in BMC Medicine. Prednisolone, taken without any antiviral therapy, postponed the loss of T-cells that leads to AIDS in 50% of HIV sufferers by between 2 and 10 years.... view more (2004-04-30)

Scripps Research scientists shed new light on how antibodies fight HIV
By furthering scientists' understanding of the molecular mechanisms that separate the minority of successful HIV antibodies from the majority of ineffective antibodies, the work may have implications for future attempts to design an HIV vaccine.   view more (2007-09-07)

EDCTP welcomes G8 support for HIV/AIDS vaccine development
On 10th June 2004 during this year's summit in Sea Island, Georgia, the G8 Leaders called for the establishment of a Global HIV Vaccine Enterprise: a virtual consortium to accelerate HIV vaccine development by enhancing coordination, information sharing, and global collaboration. The EDCTP is... view more (2004-06-11)

Viral genetic differences are possible key to HIV dementia
The study of 18 HIV-positive subjects shows that HIV in the brain and central nervous system is genetically different from HIV that lives in the blood and peripheral tissues.   view more (2006-07-26)

Anti-HIV gel proven safe, tolerable for women
An experimental anti-HIV gel is safe for women to use on a daily basis, according to researchers at the University of Alabama at Birmingham (UAB) and the University of Pittsburgh School of Medicine.   view more (2008-02-26)

Landmark study defines benefits of early HIV testing and treatment for infected infants
Testing very young babies for HIV and giving antiretroviral therapy (ART) immediately to those found infected with the virus dramatically prevents illness and death, according to a report in the New England Journal of Medicine.   view more (2008-11-20)

New Approaches To HIV Treatment In Less-developed Countries (pp 404, 410)
Two Viewpoint articles in this week's issue of THE LANCET highlight how the use of highly-active antiretroviral therapy (HAART) for HIV-1 treatment - currently only widely available in industrialised countries - could become accessible in less-developed settings. Both articles suggest new... view more (2001-08-01)

Gene Variation Can Lower Susceptibility To HIV Infection
Researchers at The University of Manchester have identified small variations in a gene which can determine whether a person contracts HIV or develops AIDS. Professor Bill Ollier, and Dr Ali Hajeer, of the ARC Epidemiology Unit at The University of Manchester, have found new variants of the RANTES... view more (2000-11-21)

Fat on chest and upper back increases risk of insulin resistance
Upper trunk fat -- deposits of fat on the chest and back -- is associated with an increased risk of insulin resistance, a condition that is a precursor of type 2 diabetes, according to a study led by researchers at the San Francisco VA Medical Center (SFVAMC).   view more (2007-08-20)

HIV persists in the gut despite long-term HIV therapy
Even with effective anti-HIV therapies, doctors still have not been able to eradicate the virus from infected individuals who are receiving such treatments, largely because of the persistence of HIV in hideouts known as viral reservoirs.   view more (2008-02-14)

Pregnancy may slow -- not accelerate -- progression to AIDS
A new study may help put to rest fears that pregnancy accelerates progression to full-blown AIDS in women with HIV receiving antiretroviral therapy.   view more (2007-09-20)

HIV and malaria combine to adversely affect pregnant women and their infants
University of Toronto researchers have uncovered the basis by which pregnant women protect themselves against malaria and have also discovered how the HIV virus works to counteract this defence. The research could lead to improved vaccines for pregnant women in malaria-ravished regions.   view more (2007-05-30)

A clue from macaques yields evidence for impaired retroviral defense genes in humans
Researchers Harmit Malik and Michael Emerman and colleagues at the Fred Hutchinson Cancer Research Center have found that a surprisingly large fraction of humans may be impaired in the function of a recently discovered arm of the body's defense against invading retroviruses such as HIV.   view more (2006-01-10)

Gene variant found in those with African ancestry increases odds of HIV infection
A variant of a gene found only in people of African ancestry increases the odds of becoming infected with the human immunodeficiency virus (HIV-1) by 40 percent, according to a long-term study of African Americans reported in the journal Cell Host & Microbe, a publication of Cell Press.   view more (2008-07-17)

HIV is a 'double hit' to the brain
New evidence reported in the August issue of Cell Stem Cell, a publication of Cell Press, offers a novel perspective on how the HIV/AIDS virus leads to learning and memory deficits, a condition known as HIV-associated dementia.   view more (2007-08-16)

Hormonal contraception does not appear to increase HIV risk
Using hormonal contraception does not appear to increase women's overall risk of infection with the AIDS virus, report the authors of a large study commissioned by the National Institute of Child Health and Human Development of the National Institutes of Health.   view more (2006-12-08)
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