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Defense peptide found in primates may block some human HIV transmissions
As primates evolved 7 million years ago, the more advanced species stopped making a protein that University of Central Florida researchers believe can effectively block the HIV-1 virus from entering and infecting blood cells. view more (2006-08-10)
HIV vaccine takes different tack to boosting immune response
esearchers at Baylor College of Medicine (BCM) in Houston have reason to believe their unorthodox vaccine could one day help to prevent or control HIV infection. view more (2006-01-03)
HIV accessory protein disables host immunity via receptor-protein intermediary
Researchers at the University of Pennsylvania School of Medicine discovered that an HIV-1 accessory protein called Vpr destroys the host cell's ability to survive by binding to a host receptor. view more (2006-03-31)
Science commentary stresses need for collaboration at local level in HIV-prevention studies
Clinical trials of drugs intended to prevent HIV infection in high-risk populations must be developed and carried out in close collaboration with the local communities and national governments of the countries in which they are conducted, according to 18 international leaders in HIV prevention writing in the current (Sept. 30, 2005) issue of... view more... (2005-10-03)
New insights into vaccination for HIV
A group of Australian researchers at the Universities of Melbourne and New South Wales have developed new tools and paradigms to understand immune evasion from HIV. view more (2008-01-25)
Mayo Clinic boosts immune system
Mayo Clinic researchers have discovered a way to dramatically boost the output of immune system cells from the thymus, which may lead to improved cancer vaccines, as well as to ways to otherwise strengthen immune responses. view more (2005-09-23)
Landmark discovery of a Kaposi's sarcoma-associated herpesvirus receptor
Researchers at the National Institute of Allergy and Infectious Disease (NIAID), a component of the National Institutes of Health (NIH), have identified a critical human cell surface molecule involved in infection by Kaposi's sarcoma herpesvirus (KSHV), the virus that causes Kaposi's sarcoma and certain forms of lymphoma. view more (2006-04-07)
Alcohol and high-risk sexual behaviors in Botswana
Heavy alcohol consumption is strongly and consistently associated with sexual risk behaviors in both men and women in Botswana, according to one of the few research studies on the topic in sub-Saharan Africa. view more (2006-10-10)
New protein target may advance design of HIV and cancer drugs
Using small molecules containing platinum, Virginia Commonwealth University Massey Cancer Center researchers have created a process to inhibit a class of proteins important in HIV and cancer. view more (2006-05-31)
Molecular steps involved in the creation of gene-silencing MicroRNAs identified
First discovered only a few brief years ago, microRNAs are small, remarkably powerful molecules that appear to play a pivotal role in gene silencing, one of the body's main strategies for regulating its genome. A scant 22 nucleotides in length, miRNAs appear to work by binding to and somehow interfering with messenger RNA, itself responsible for... view more... (2005-06-23)
'Resonance' may explain virologic failure in STI drug therapy
Researchers have been puzzled over why HIV-positive patients who have periodic, built in interruptions in their drug therapy reach a point where the therapy no longer reduces their viral loads, even in the absence of any evidence of acquired drug resistance. view more (2006-04-14)
Molecular switch may turn off immune cells that target HIV
One of the primary mysteries of the AIDS epidemic - why the immune system is unable to control HIV infection - may have been solved by an international research collaborative. view more (2006-08-21)
Anti-HIV drug has potential to prevent transmission in women
A new study from infectious disease researchers at The Miriam Hospital and Brown Medical School finds that a drug already given orally to treat HIV is also safe when applied as a vaginal microbicide gel. view more (2006-02-10)
Immune deficiency linked to a type of eye cancer
The incidence of squamous cell eye cancer is greater among kidney transplant patients and people with human immunodeficiency virus (HIV) than the general public, which suggests the disease is associated with immune deficiency. view more (2007-08-15)
A new step towards an AIDS vaccine
Progressive disease after HIV infection is inversely correlated with the presence of plasmacytoid dendritic cells (pDCs), a subset of the dendritic cell family and the major producers of type 1 interferon in the body. view more (2005-10-14)
Interfering RNA silences genes in 'slippery' immune cells
A technical advance in laboratory techniques may provide biology researchers broader access to RNA interference, a process of blocking the activity of targeted genes. view more (2006-05-09)
How HIV 'exhausts' killer T cells
American and South African scientists working at the epicenter of the AIDS epidemic in South Africa have discovered how the human immunodeficiency virus (HIV) "exhausts" killer T cells that would otherwise attack the virus. view more (2006-08-21)
AIDS inflicts specific pattern of brain damage, reveals UCLA/Pittsburgh imaging study
A new UCLA/University of Pittsburgh imaging study for the first time shows the selective pattern of destruction inflicted by AIDS on brain regions that control motor, language and sensory functions. view more (2005-10-11)
Researchers seek to solve mystery of natural HIV control
An international, multi-institutional research consortium is seeking to discover how a few HIV-infected individuals are naturally able to suppress replication of the virus. view more (2006-08-17)
Study holds promise for new way to fight AIDS
For years researchers have been trying to understand how a few HIV-infected patients naturally defeat a virus that otherwise overwhelms the immune system. view more (2006-11-02)
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