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New lab mice pave way for novel studies of human infection
A new type of laboratory mouse developed at UT Southwestern Medical Center can fight certain infections the same way humans do, making the rodents very useful for novel studies of human-pathogen interaction and developing disease therapies. View News Article (2006-10-23)


A new step towards an AIDS vaccine
Progressive disease after HIV infection is inversely correlated with the presence of plasmacytoid dendritic cells (pDCs), a subset of the dendritic cell family and the major producers of type 1 interferon in the body. View News Article (2005-10-14)


Study holds promise for new way to fight AIDS
For years researchers have been trying to understand how a few HIV-infected patients naturally defeat a virus that otherwise overwhelms the immune system. View News Article (2006-11-02)


Molecular steps involved in the creation of gene-silencing MicroRNAs identified
First discovered only a few brief years ago, microRNAs are small, remarkably powerful molecules that appear to play a pivotal role in gene silencing, one of the body's main strategies for regulating its genome. A scant 22 nucleotides in length, miRNAs appear to work by binding to and somehow interfering with messenger RNA, itself responsible for translating genes into proteins. View News Article (2005-06-23)


Researchers seek to solve mystery of natural HIV control
An international, multi-institutional research consortium is seeking to discover how a few HIV-infected individuals are naturally able to suppress replication of the virus. View News Article (2006-08-17)


Molecular switch may turn off immune cells that target HIV
One of the primary mysteries of the AIDS epidemic - why the immune system is unable to control HIV infection - may have been solved by an international research collaborative. View News Article (2006-08-21)


Computational model simulates AZT metabolism in mitochondria
Researchers at the Virginia Bioinformatics Institute (VBI) at Virginia Tech have developed a computational model that allows scientists to better understand the metabolism and toxicity of the HIV/AIDS drug zidovudine (azidothymidine, AZT). View News Article (2006-07-25)


Wild gorillas carriers of a SIV virus close to the AIDS virus
In 2005, 40.3 million people in the world, including 25.8 million in Sub-Saharan Africa, were living with HIV. The question of the origin of HIV-1, responsible for the AIDS pandemic, has been stimulating the scientific community for many years. View News Article (2006-11-14)


Controlling neglected tropical diseases could help make poverty history
"The big three" infections AIDS, TB and malaria have caught the world's attention but other disabling and fatal infectious diseases in Africa are being ignored, say three eminent tropical disease researchers in the international health journal PLoS Medicine. View News Article (2005-10-11)


Interfering RNA silences genes in 'slippery' immune cells
A technical advance in laboratory techniques may provide biology researchers broader access to RNA interference, a process of blocking the activity of targeted genes. View News Article (2006-05-09)

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