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Novel candidate biomarker for heart failure also strongly predicts risk of death
A potential new biomarker for heart failure may be more powerful than established measures in identifying patients at increased risk for death from several causes. view more (2007-08-07)
When statins aren't enough: New trial drug points to better management of coronary heart disease
Despite widespread use of cholesterol-lowering drugs, a significant number of cardiac patients continue to suffer heart attacks and stroke. Researchers theorize that high levels of an enzyme found in coronary plaques may be to blame, by making plaques more likely to rupture and block blood flow. view more (2008-05-09)
Blood test predicts cardiac events and death in heart patients
A simple blood test for the protein NT-proBNP accurately predicts the risk of heart attack, heart failure, stroke, and death in patients with known cardiovascular disease, according to a study led by a researcher at the San Francisco VA Medical Center. view more (2007-01-10)
Patient outcomes linked to biomarker levels by quantitative technology
Researchers in the Department of Pathology at Yale University School of Medicine report that when using current pathology methods of biomarker detection, the concentration of antibodies used dramatically alters the apparent relationship of biomarker level to clinical outcome. view more (2005-12-21)
New research may lead to earlier diagnosis and treatment of primary biliary cirrhosis in families
Mayo Clinic researchers have found that first-degree relatives (i.e., parents, siblings, children) of patients with primary biliary cirrhosis (PBC) are more likely to have the biomarker of the disease in their blood. view more (2007-09-11)
Researchers develop new method to test for lung cancer
Researchers from Boston University School of Medicine have developed a new "clinicogenomic model" to accurately test for lung cancer. view more (2008-04-02)
A probable cause for Parkinson's?
Parkinson's, Alzheimer's, Lou Gehrig's disease and other brain disorders are among a growing list of maladies attributed to oxidative stress, the cell damage caused during metabolism when the oxygen in the body assumes ever more chemically reactive forms. view more (2006-06-28)
Jefferson researchers find potential biomarket for heart failure
A team of cardiology researchers at Thomas Jefferson University has determined that GRK2, a protein that plays an important regulatory role in heart failure, is elevated in patients with failing hearts when compared to patients with normal heart function. view more (2006-09-12)
Link between stress and heart disease may be premature
It has often been claimed that psychological stress is an important cause of heart disease, but a study in this week's BMJ shows that previous research may have been misleading. Researchers measured self-assessed stress amongst middle-aged Scottish men working in and around Glasgow in the early 1970s. These men were then followed for more than... view more... (2002-05-22)
Early warning for acute kidney injury
Clinicians currently lack advance warning of acute kidney injury (AKI) for patients where kidney injury timing is unknown. view more (2007-08-02)
New biomarker may predict leukemia aggressiveness
Scientists at the University of California, San Diego and the Moores UCSD Cancer Center have evidence of a potential new biomarker to predict the aggressiveness of an often difficult-to-treat form of leukemia. view more (2009-04-20)
Marking anorexia with a brain protein
Eating disorders are frequently seen as psychological or societal diseases, but do they have an underlying biological cause? A new study shows that the levels of a brain protein differ between healthy and anorexic women. view more (2009-06-24)
Use of archived specimens in biomarker studies
Researchers propose a more efficient system using archived specimens for the evaluation of prognostic and predictive biomarkers in a new commentary published online October 8 in the Journal of the National Cancer Institute. view more (2009-10-09)
Alcoholism Is A Major, Neglected Problem In Patients With Heart Disease.
Some epidemiological studies suggest that moderate alcohol consumption decreases the risk of coronary heart disease. However, long-term excessive alcohol drinking is considered to be a major cause for worsening of heart disease. A group of Greek investigators, headed by George Christodoulou, Professor and Chairman of Psychiatry at the University... view more... (2000-12-28)
Improved predictive value of biomarkers in HF makes earlier diagnosis and better management possible
With an ever ageing population and more people surviving a heart attack, heart failure is now the world's most prevalent chronic cardiovascular disease. Yet despite improvements in its diagnosis and management, heart failure remains a stubbornly incurable condition with a poor prognosis, largely amenable to little more than palliative therapy. view more (2009-03-30)
Biomarker of breathing control abnormality associated with hypertension and stroke
A study in the July 1 issue of the journal SLEEP identified a distinct ECG-derived spectrographic phenotype, designated as narrow-band elevated low frequency coupling (e-LFCNB), that is associated with prevalent hypertension, stroke, greater severity of sleep disordered breathing and sleep fragmentation in patients suffering from obstructive sleep... view more... (2009-07-01)
Heart disease risk in British men is overestimated
Current scoring methods over-predict the risk of death from coronary heart disease in British men, according to a study in this week's BMJ. view more (2003-11-26)
Southampton study aims to pinpoint heart disease genes
REF: 99/53 15 APRIL 1999 view more (1999-05-26)
Sex inequalities found in primary care treatment of heart disease
A study in this week's BMJ reports that treatment of heart disease in primary care is systematically biased towards men, despite no suggestion of sex differences in the management of these patients in England's national service framework for coronary heart disease. Data for over 5,000 men and women with ischaemic heart disease in the Trent health... view more... (2001-04-03)
VBI researchers develop new method for breast cancer biomarker discovery
Three researchers from the Virginia Bioinformatics Institute (VBI) at Virginia Tech have developed and evaluated a new one-step bioanalytical approach that allows them to profile in detail complex cellular extracts of proteins. view more (2009-06-10)
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