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Exercise training in ordinary people affects the activity of 500 genes
A new study from Karolinska Institutet in Stockholm shows that hundreds of genes in the thigh muscle are activated in regular cycle training. The study also reveals that great differences in training response may be due to the ability in some people to activate their genes much more forcefully. The study is published May 2 in FASEB Journal. It... view more... (2005-05-03)

Exercise training in ordinary people affects the activity of 500 genes
A new study from Karolinska Institutet in Stockholm shows that hundreds of genes in the thigh muscle are activated in regular cycle training. The study also reveals that great differences in training response may be due to the ability in some people to activate their genes much more forcefully. The study is published May 2 in FASEB Journal.   view more (2005-05-02)

Researchers discover 'sticky' proteins fuse adult stem cells to cardiac muscle, repairing hearts
Cardiologists are increasingly using adult stem cells in clinical trials to repair hearts following heart attacks, but no one has understood how the therapy actually works.   view more (2007-02-16)

Garlic may protect the heart after heart surgery
Raw garlic consumption may help limit the damage done to the heart after surgery because if its natural antioxidant properties, according to a new study published in BMC Pharmacology. After a heart attack it is important to restore the flow of blood to the heart so that damage to the heart muscle can be minimised. However, the return of blood... view more... (2002-09-09)

Gene, stem cell therapy only needs to be 50 percent effective to create a healthy heart
Heart disease is the leading cause of death in the United States and greatly affects the quality and length of life for individuals with specific forms of muscular dystrophy.   view more (2007-11-01)

Pittsburgh scientists identify human source of stem cells with potential to repair muscle
For the first time, scientists at Children's Hospital of Pittsburgh of UPMC have discovered a unique population of adult stem cells derived from human muscle that could be used to treat muscle injuries and diseases such as heart attack and muscular dystrophy.   view more (2007-09-05)

U of MN uses robotic surgery techniques in cardiac cell therapy research
Researchers at the University of Minnesota were successful in using robotic surgery to deliver stem cell treatment to damaged heart tissue in pigs.   view more (2006-08-01)

High blood pressure causes pathological scars in the heart
Fibrosis (scar tissue formation) is the determinant lesion in the subsequent evolution of the heart in a patient with high blood pressure. This item appeared in the latest edition of Nature Clinical Practice Cardiovascular Medicine, a journal that is part of the Nature group. The article published heart research recently carried out at the... view more... (2005-05-25)

Study: Fountain of youth for your heart?
An age-related decline in heart function is a risk factor for heart disease in the elderly. While many factors contribute to a progressive age-related decline in heart function, alterations in the types of fuels the heart uses to produce energy also play important roles.   view more (2007-11-05)

Gladstone scientists identify key factors in heart cell creation
Scientists at the Gladstone Institute of Cardiovascular Disease have identified for the first time key genetic factors that drive the process of generating new heart cells.   view more (2009-04-27)

Research uncovers new steps on pathway to enlarged heart
Researchers have new insight into the mechanisms that underlie a pathological increase in the size of the heart. The research, published by Cell Press in the October 24th issue of the journal Molecular Cell, may lead to the development of new strategies for managing this extremely common cardiac ailment that often leads to heart failure.   view more (2008-10-24)

Massage after exercise myth busted by Queen's research team
A Queen's University research team has blown open the myth that massage after exercise improves circulation to the muscle and assists in the removal of lactic acid and other waste products.   view more (2009-05-08)

Surprise - Cholesterol May Actually Pose Benefits, Study Shows
If you're worried about high cholesterol levels and keeping heart-healthy as you get older, don't push aside bacon and eggs just yet. A new study says they might actually provide a benefit.   view more (2008-01-10)

Protein changes in heart strengthen link between Alzheimer's disease and chronic heart failure
A team of U.S., Canadian and Italian scientists led by researchers at Johns Hopkins report evidence from studies in animals and humans supporting a link between Alzheimer's disease and chronic heart failure, two of the 10 leading causes of death in the United States.   view more (2009-11-16)

Drug for erectile dysfunction improves heart function in young heart-disease patients
Heart function significantly improved in children and young adults with single-ventricle congenital heart disease who have had the Fontan operation following treatment with sildenafil, a drug used to treat erectile dysfunction and pulmonary hypertension, say researchers from The Children's Hospital of Philadelphia.   view more (2009-11-19)

Key to zebrafish heart regeneration uncovered
When a portion of a zebrafish's heart is removed, the dynamic interplay between a mass of stem cells that forms in the wound and the protective cell layer that covers the wound spurs the regeneration of functional new heart tissue.   view more (2006-11-03)

U of MN researchers develop mouse model for muscle disease
Researchers from the University of Minnesota have identified the importance of a gene critical to normal muscle function, resulting in a new mouse model for a poorly understood muscle disease in humans.   view more (2006-09-06)

Researchers describe mechanisms by which capon gene causes heart rhythm disturbances
research team from the Cedars-Sinai Heart Institute, Johns Hopkins University and China Medical University and Hospital in Taiwan have described for the first time the mechanisms by which variants of a specific gene, CAPON or NOS1AP, can disrupt normal heart rhythm. Until recently, CAPON was not even suspected of existing in heart tissue or... view more... (2008-03-04)

'Mighty mice' made mightier
The Johns Hopkins scientist who first showed that the absence of the protein myostatin leads to oversized muscles in mice and men has now found a second protein, follistatin, whose overproduction in mice lacking myostatin doubles the muscle-building effect.   view more (2007-08-29)

Early heart attack therapy with bone marrow extract improves cardiac function
A UCSF study for the treatment of heart failure after heart attack found that the extract derived from bone marrow cells is as effective as therapy using bone marrow stem cells for improving cardiac function, decreasing the formation of scar tissue and improving cardiac pumping capacity after heart attack.   view more (2009-06-30)
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