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Heart Muscle Current Events | Heart Muscle News | 8

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Research shows promise for potential new gene therapy strategy for muscle-wasting diseases
Investigators in The Research Institute at Nationwide Children's Hospital have identified the role of a protein that could potentially lead to new clinical treatments to combat musculoskeletal diseases, including Duchenne muscular dystrophy (DMD).   view more (2008-03-11)

First study transplanting angina patients' purified stem cells shows safety and symptom relief
The first U.S. study to transplant a potent form of purified adult stem cells into the heart muscle of patients with severe angina provided evidence that the procedure is safe and produced a reduction in angina pain as well as improved functioning in patients' daily lives.   view more (2007-06-27)

Vitamin D, a key milk nutrient, linked to better muscle power
Young female athletes could have yet another reason to grab a glass of vitamin D-rich milk. Not only does vitamin D work with calcium to keep bones strong, but researchers now found that teenage girls with higher vitamin D levels may be able to jump higher and faster than their peers with lower levels.   view more (2009-02-05)

Debate focuses on door-to-balloon time in heart attack treatment
In the treatment of heart attack, the 90-minute goal for inflation of an angioplasty balloon in a blocked coronary artery to restore normal blood flow is so revered it's been codified in clinical guidelines, accreditation standards, and pay-for-performance programs.   view more (2007-05-14)

Ace Inhibitors Could Slow Muscle Decline (p 926)
Angiotensin-converting enzyme (ACE) inhibitors, a class of drugs used to lower blood pressure, could also be protective against the decline in muscle strength in elderly women suggest authors of a study in this week's issue of THE LANCET. ACE inhibitors are known to prevent the decline in physical function in patients with congestive heart failure... view more... (2002-03-13)

CU-Boulder research team identifies stem cells that repair injured muscles
A University of Colorado at Boulder research team has identified a type of skeletal muscle stem cell that contributes to the repair of damaged muscles in mice, which could have important implications in the treatment of injured, diseased or aging muscle tissue in humans, including the ravages of muscular dystrophy.   view more (2009-03-06)

ESC Congress 2003: Stem cells therapy is a safe tool for mending broken hearts
IMPORTANT: This press release accompanies both a presentation and an ESC press conference given at the ESC Congress 2003. Written by the investigator himself/herself, this press release does not necessarily reflect the opinion of the European Society of Cardiology ESC Congress 2003: Stem cells - A tool for mending broken hearts? We have shown that... view more... (2003-09-01)

Mutation responsible for cystic fibrosis also involved in muscle atrophy
Patients with cystic fibrosis (CF) usually experience significant muscle loss, a symptom traditionally considered to be a secondary complication of the devastating genetic disease.   view more (2009-07-31)

High-fat diet impairs muscle health before impacting function
Skeletal muscle plays a critical role in regulating blood sugar levels in the body. But few studies have comprehensively examined how obesity caused by a high-fat diet affects the health of muscle in adolescents who are pre-diabetic.   view more (2009-10-06)

New 'molecular switch' protein protects the heart from major cardiovascular damage
It's just one little amino acid, but it makes all the difference in protecting the heart from the harmful effects of heart attack and cardiac failure. Researchers from the University of Michigan Medical School suggest this amino acid, called histidine, could be the key to a new therapy for cardiovascular disease.   view more (2006-01-23)

Gene therapy reverses genetic mutation responsible for heart failure in muscular dystrophy
University of Pittsburgh investigators have for the first time used gene therapy to successfully treat heart failure and other degenerative muscle problems in an animal model that is genetically susceptible to a human muscular dystrophy.   view more (2005-10-26)

Loss of nerve cells may link constipation with achalasia of the oesophagus
Patients who have difficulty swallowing food may also be more likely to suffer from constipation, according to a preliminary study published this week in BMC Gastroenterology. The research suggests that patients with achalasia of the oesophagus, associated with a loss of nerve cells in the muscle surrounding the oesophagus, may also lose nerve... view more... (2003-10-13)

Mental stress effects on heart more common than previously known
Even when heart disease patients can pass stress tests done on a treadmill or with chemical stressors after treatment, their hearts may still suffer silent ischemia during mental stress.   view more (2006-03-07)

Abnormal fat metabolism underlies heart problems in diabetic patients
Heart disease hits people with diabetes twice as often as people without diabetes. In those with diabetes, cardiovascular complications occur at an earlier age and often result in premature death, making heart disease the major killer of diabetic people. But why is heart disease so prevalent among diabetics?   view more (2007-08-13)

Rescuing injured hearts by enhancing regeneration
Using a two-drug approach, researchers at Children's Hospital Boston have demonstrated that it may be possible to rescue heart function after a heart attack and protect the heart from scarring.   view more (2006-10-10)

UF scientists test improved gene therapy method for hereditary heart conditions
A new way of delivering corrective genes with a single injection into a vein holds promise for long-lasting treatments of hereditary diseases of the heart.   view more (2006-07-31)

Researchers identify gene associated with muscular dystrophy-related vision problems
Skeletal muscle disease and vision deficits might seem unrelated, but a frog model of muscular dystrophy shows it is not such a leap.   view more (2009-04-21)

Angioplasty reduces long-term cardiac risk among heart patients with 'silent' ischemia
When compared with intensive drug therapy, percutaneous coronary intervention (PCI, angioplasty) was more beneficial in reducing the long-term risk of major cardiac events among heart attack survivors with "silent ischemia".   view more (2007-05-09)

Medical breakthrough for organ transplants and cardiovascular diseases by Flemish researchers
When a blood vessel clogs up, a localized deficiency of oxygen results, causing the surrounding tissue to die. However, working with mice, VIB scientists connected to the Katholieke Universiteit Leuven have been able to prevent muscular tissue with severe hypoxia from dying.   view more (2008-01-07)

Study explores cause of exercise intolerance in heart failure patients
A new study shows that blood flow to the legs is relatively normal in people with diastolic heart failure, suggesting other potential causes of their inability to do everyday activities.   view more (2006-11-20)
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