Hematopoietic Current Events | Hematopoietic News | 2
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St. Jude settles century-old debate on origin of mammalian network of lymphatic vessels
Investigators at St. Jude Children's Research Hospital settled a century-old debate on the origin of the mammalian lymphatic vasculature-the network of vessels and capillaries critical to various essential housekeeping functions in the body. The finding holds the promise for the development of new therapies for lymphatic system disorders, the... view more... (2007-10-04)
Survey: Few physicians support private banking of umbilical cord blood
A survey of physicians has found broad support for the position that parents should not bank their newborns' umbilical cord blood in a private blood bank unless another member of the family is at risk for a blood disease that will require a stem cell transplant. view more (2009-03-09)
Research shows cell's inactive state is critical for effectiveness of cancer treatment
A new study sheds light on a little understood biological process called quiescence, which enables blood-forming stem cells to exist in a dormant or inactive state in which they are not growing or dividing. view more (2009-01-12)
Lost in the labyrinth
Blood cells have limited lifespans, which means that they must be continually replaced by calling up reserves, and turning these into the blood cell types needed by the body. view more (2006-09-05)
Sickle cell disease corrected in human models using stem cell-based gene therapy
In a study to be published in the January 2006 issue of Nature Biotechnology, researchers led by a team of scientists at Memorial Sloan-Kettering Cancer Center have devised a novel strategy that uses stem cell-based gene therapy and RNA interference to genetically reverse sickle cell disease (SCD) in human cells. view more (2005-12-29)
Discoveries thrust cancer-initiating stem cells into a larger role in cancer biology and treatment
Recent discoveries about the role of stem cells in cancer have altered the landscape of cancer research. With each new study, scientists are learning more about cancer-initiating properties of stem cells at organ sites and throughout the body. view more (2007-04-19)
U of MN researchers identify new cord blood stem cell
Researchers at the University of Minnesota Medical School have discovered a new population of cells in human umbilical cord blood that have properties of primitive stem cells. view more (2006-02-14)
Mad-cow culprit maintains stem cells
What do mad cow disease and stem cell research have in common? Whitehead Institute scientists have found that the same protein that causes neurodegenerative conditions such as bovine spongiform encephalopathy (mad cow disease) is also important for helping certain adult stem cells maintain themselves. view more (2006-01-31)
Ago2 and hematopoiesis
Argonaute 2 (Ago2) is unique among its family: It is the only one of the four mammalian Argonaute proteins that exhibits endonuclease "slicer" activity (facilitation of miRNA-guided cleavage of target mRNA). view more (2007-07-12)
St. Jude researchers find key step in programmed cell death
Investigators at St. Jude Children's Research Hospital have discovered a dance of proteins that protects certain cells from undergoing apoptosis, also known as programmed cell death. Understanding the fine points of apoptosis is important to researchers seeking ways to control this process. view more (2008-03-03)
Mother's immune system may block fetal treatments for blood diseases
Pediatric researchers have resolved an apparent contradiction in the field of prenatal cell transplantation- a medical approach that holds future promise in correcting sickle cell disease and other serious congenital blood disorders. view more (2009-08-17)
Making flies sick reveals new role for growth factors in immunity
A Salmonella infection is not a positive experience. However, by infecting the common laboratory fruit fly Drosophila melanogaster with a Salmonella strain known for causing humans intestinal grief, researchers in the School of Life Sciences at Arizona State University have shed light on some key cell regulatory processes - with broad implications... view more... (2008-10-27)
Scientists successfully reprogram blood cells
Researchers have transplanted genetically modified hematopoietic stem cells into mice so that their developing red blood cells produce a critical lysosomal enzyme -preventing or reducing organ and central nervous system damage from the often-fatal genetic disorder Hurler's syndrome. view more (2009-11-10)
UC Davis researchers exploring gene therapy to fight AIDS
The apparent success of a case in which German doctors cured a man of AIDS using a bone marrow transplant comes as no surprise to Gerhard Bauer, a UC Davis stem cell researcher. view more (2008-12-08)
Bone marrow-derived stem cells may offer novel therapeutic option for skin disorder
Stem cells derived from bone marrow may serve as a novel therapeutic option to treat a disease called epidermolysis bullosa (EB), a disorder characterized by extraordinarily fragile skin, according to a study prepublished online in Blood, the official journal of the American Society of Hematology. view more (2008-12-05)
Can you hear me now? Scientists find previously unknown receptors on adult stem cells
For many years, researchers believed that stem cells in the bone marrow spent most of their existence in a slumber-like state, unaware of — and unaffected by — the daily battles fought by the body's immune system. view more (2006-06-21)
Cloned mice created from fully differentiated cells, a milestone in cloning research
New research dismisses the notion that adult stem cells are necessary for successful animal cloning, proving instead that cells that have completely evolved to a specific type not only can be used for cloning purposes, but they may be a better and more efficient starting point. view more (2006-10-02)
Immune therapy can protect against or treat later lymphoma
Specially developed immune system cells that target the common Epstein-Barr virus can protect immune-suppressed bone marrow transplant recipients against lymph system disease and cancers that arise from the viral infection. view more (2009-11-03)
Predicting acute GVHD by gene expression could improve liver stem cell transplant outcomes
Many cell transplants involve the use of stem cells from another human being (known as an allograft), which raises the major concern of the potential for acute graft-versus-host disease (GVHD). view more (2008-07-21)
Predicting the risk of a common fungal infection after stem cell transplantation
In silico genetic analysis in mice has led to the discovery of a gene affecting susceptibility to a severe fungal infection in transplant recipients. view more (2008-06-20)
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