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Toxic milk
In the August 1 issue of G&D, Dr. Ronald Evans (Salk Institute) and colleagues report on their discovery that mutations in the mouse gene encoding PPARγ adversely affect lactation milk quality, and have serious health consequences for nursing pups.   view more (2007-07-24)

Molecular 'marker' on stem cells aids research, perhaps therapies
A sugar molecule present on embryonic stem cells also has been found on the surface of a type of adult stem cell, a discovery that may help researchers isolate and purify adult stem cells for use in therapies aimed at bone healing, tendon repair and cartilage regeneration, researchers at UT... view more (2006-12-04)

Hepatitis C increases risk of non-Hodgkin lymphoma
Hepatitis C infection is associated with an increased risk of non-Hodgkin lymphoma (malignancy involving lymphatic tissue) of 20 percent to 30 percent, and a three-fold increase in the risk of another type of lymphoma, according to a study in the May 9 issue of JAMA.   view more (2007-05-09)

Protein key to control, growth of blood cells
New research sheds light on the biological events by which stem cells in the bone marrow develop into the broad variety of cells that circulate in the blood. The findings may help improve the success of bone marrow transplants and may lead to better treatments for life-threatening blood diseases.   view more (2008-08-14)

Human embryonic stem cells developed from 4-cell embryo; world first may lessen ethical concerns
For the first time in the world scientists have succeeded in developing human embryonic stem cells (hESCs) from a single cell, or blastomere, of a 4-cell stage embryo.   view more (2008-07-09)

New Stem Cell Program : Funds Awarded to Nervous System Projects and Stem Cell Bank Networks
Nine projects and two extensive networks will share 44 million Swedish kronor (SEK) in research funds, the first grants awarded by Sweden's new Joint Program on Stem Cell Research. Of nearly 50 applicants, 11 received grants. Several of the funded projects address the nervous system. Diabetes is... view more (2002-09-05)

NSAIDs: Painkillers, inflammation inhibitors, anti-cancer drugs and new de-methylating agents
Researchers at the National Sun Yat-Sen University and Kaohsiung Medical University, Kaohsiung, Taiwan have revealed a new mechanism by which nonsteroidal anti-inflammatory drugs (NSAIDs) attenuate tumor invasion and metastasis.   view more (2008-03-27)

MicroRNA works with Ago2 protein to regulate blood cell development
MicroRNAs became the stars of the RNA universe when, in 2001, scientists found that these short RNAs can control whether or not genes are expressed.   view more (2007-07-27)

Study identifies molecule essential for proper localization of blood stem cells
Scientists at the Massachusetts General Hospital (MGH) Center for Regenerative Medicine and the Harvard Stem Cell Institute (HCSI) have defined a molecule that dictates how blood stem cells travel to the bone marrow and establish blood and immune cell production.   view more (2006-01-16)

Adult stem cells may be beneficial for certain cardiovascular disorders and autoimmune diseases
A review of previously published research suggests that stem cells harvested from an adult's blood or marrow may provide treatment benefit to select patients for some autoimmune diseases and cardiovascular disorders.   view more (2008-02-27)

Effects of aging in stem cells
There is little disagreement that the body's maintenance and repair systems deteriorate with age, even as there is plenty of disagreement as to why.   view more (2007-07-24)

Grafts against cancer
A research team led by Prof. Claude Perreault, Université de Montréal, is announcing a major discovery in Genomics. This will generate a fundamental impact on the treatment of blood cancers (leukemias and lymphomes) by means of peripheral blood T-cell grafts.   view more (2007-02-02)

Aspartame is safe, study says
Looking at more than 500 reports, including toxicological, clinical and epidemiological studies dating from 1970's preclinical work to the latest studies on the high-intensity sweetener, along with use levels and regulations data, an international expert panel from 10 universities and medical... view more (2007-09-12)

Researchers find stem-cell therapy effective in targeting metastatic cancer
Patients with advanced cancer that has spread to many different sites often do not have many treatment options, since they would be unable to tolerate the doses of treatment they would need to kill the tumors.   view more (2006-12-21)

Cells on path to becoming mature T-cells more flexible than commonly thought
Contrary to the currently accepted model of T-cell development, researchers at the University of Pennsylvania School of Medicine have found that juvenile cells on their way to becoming mature immune cells can develop into either T cells or other blood-cell types versus only being committed to the... view more (2008-04-10)

Trial at Jefferson shows new drug may help cancer patients who need stem cell transplants
A new drug may help cancer patients mobilize the cells necessary to restore their blood-forming system after high-dose chemotherapy, according to results from a clinical trial at the Kimmel Cancer Center at Thomas Jefferson University Hospital in Philadelphia and at other centers across the nation.   view more (2005-09-09)

Press release from Nature and the Nature Research Journals
This Press Release contains: ·Summaries of newsworthy papers: NANOSCALE ARMS CONTROL - Nature Materials STEPMOTHER OF PEARL - Nature Materials COMBINATION VACCINE DELIVERS DOUBLE BLOW - Nature Medicine STEM CELL ENGRAFTMENT SUCCESS DOES NOT ENSURE LONG-TERM SURVIVAL - Nature Immunology Mention of... view more (2003-05-27)

Ireland Cancer Center researchers advance stem cell gene therapy
Ireland Cancer Center of University Hospitals Case Medical Center researchers have recently made great strides in stem cell gene therapy research by transferring a new gene to cancer patients, via their own stem cells, with the ultimate goal of being able to use stronger chemotherapy treatment with... view more (2007-12-13)

Pittsburgh scientists identify human source of stem cells with potential to repair muscle
For the first time, scientists at Children's Hospital of Pittsburgh of UPMC have discovered a unique population of adult stem cells derived from human muscle that could be used to treat muscle injuries and diseases such as heart attack and muscular dystrophy.   view more (2007-09-05)

New study expands understanding of the role of RNA editing in gene control
For many years, scientists thought gene activity was relatively straightforward: Genes were transcribed into messenger RNA, which was processed and translated into the proteins of the body.   view more (2005-12-27)

Studies find general mechanism of cellular aging
Three separate studies confirm a gene that suppresses tumor cell growth also plays a key role in aging.   view more (2006-09-07)

OHSU study says stem cell 'fusion' occurs in tumors
An Oregon Health & Science University study is adding credence to an increasingly popular theory that fusion is what bonds stem cells with bone marrow cells to regenerate organ tissue.   view more (2006-05-10)

A Molecular Basis for Cocaine Abuse: PLoS Biology Press Release
This Is Your Fly's Brain on Drugs Cocaine addiction wreaks profound changes on the brain, hijacking reward circuits and depressing inhibitory loops to the point that drug seeking and taking become central drivers of behavior. While mammalian models are useful for mapping out the neural complexity... view more (2004-11-16)

UCLA researchers find blood stem cells originate and are nurtured in the placenta
Solving a long-standing biological mystery, UCLA stem cell researchers have discovered that blood stem cells, the cells that later differentiate into all the cells in the blood supply, originate and are nurtured in the placenta.   view more (2008-03-06)

Clinical trial to test stem cell approach for children with brain injury
A unique clinical trial will gauge the safety and potential of treating children suffering traumatic brain injury with stem cells derived from their own bone marrow starting early next year.   view more (2005-12-21)
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