Hemochromatosis Current Events | Hemochromatosis News
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Iron overload
One in every three hundred people in the US and UK has the potential to develop hemochromatosis, a disorder which overloads the body with iron. So why do only some of them go on to develop the disease? American scientists have been studying the genetic make-up of patients with hemochromatosis, a potentially fatal disease. Sufferers have high... view more... (2001-04-04)
Study sheds important new light on inherited disorder causing iron overload
Research in today's New England Journal of Medicine (www.nejm.org) shows hereditary hemochromatosis is much more common than previously thought and will spur more study to determine who is most likely to develop complications from the debilitating and potentially fatal disease, write two faculty members at the Saint Louis University School of... view more... (2008-01-17)
Europe's most common genetic disease is a liver disorder
Much less widely known than the dangerous consequences of iron deficiencies is the fact that too much iron can also cause problems. The exact origin of the genetic iron overload disorder hereditary hemochromatosis [HH] has remained elusive. view more (2008-02-07)
Hyperferritinemia is another surrogate marker of advanced liver disease
High serum ferritin, being a hallmark of hereditary hemochromatosis , is frequently found in chronic hepatitis C, alcoholic or non-alcoholic steatohepatitis and non-alcoholic fatty liver disease patients. view more (2009-05-13)
After a 40-year search, a hormone controlling iron metabolism in mammals is finally identified
Iron is vital for cells, because it catalyzes key enzyme reactions; it is also crucial for respiration, fixing atmospheric oxygen to hemoglobin in red blood cells. Iron deficiency can lead to severe anemia, with inadequate tissue oxygenation. An excess of iron is also toxic, as it facilitates the generation of free radicals that can attack the... view more... (2002-04-03)
What makes the body absorb too much iron? Researchers at EMBL and Harvard gain new insights into the most common inherited disease in the Western world
Like most nutrients, iron is good for people - in the right doses. When the body has enough iron, our cells stop absorbing it from food; if there is too little, they absorb more. This system breaks down in the most common inherited disease in the Western world: hemochromatosis, which affects about one in every 250 people and is often fatal if it... view more... (2003-04-29)
Unexpected link between gene in liver and iron overload
A new study in the December Cell Metabolism reveals an unexpected connection between a tumor suppressor gene in the liver and the normally careful control over the amount of iron absorbed from the diet. view more (2005-12-07)
Hemochromatosis, Inflammation and Anemia: Researchers Discover a Surprising Link
Patients with inflammatory diseases such as arthritis, chronic infections and some types of cancer, often become anemic - a condition called anemia of chronic disease (ACD). While ACD rarely kills patients, it can make their lives miserable. A discovery at EMBL, in collaboration with researchers at Children's Hospital Boston and Harvard Medical... view more... (2004-04-15)
Key site in iron metabolism aids in diagnosing anemia of chronic disease
University of Utah School of Medicine researchers have developed a new tool that facilitates diagnosis of anemia related to chronic illness, as well as diseases of iron overload. The results of a study detailing the new tool are published in the August 2008 issue of the journal Cell Metabolism, a publication of Cell Press. view more (2008-08-06)
Carbon nanotubes that detect disease-causing mutations developed by Pitt researcher
University of Pittsburgh researcher Alexander Star and colleagues at California-based company Nanomix, Inc., have developed devices made of carbon nanotubes that can find mutations in genes causing hereditary diseases. view more (2006-01-26)
New ways to prevent stroke and reduce excess iron in sickle cell anemia
St. Jude Children's Research Hospital will lead a national Phase III clinical trial to investigate whether a new combination treatment can prevent a secondary stroke in children with sickle cell anemia (SCA) and eliminate the need for nightly injections with a drug that reduces iron overload in these patients. view more (2005-09-01)
UB Scientist Discovers Novel Iron-Copper Alliance
Iron is the workhorse of trace minerals. An essential component of red blood cells, disruption of iron levels in the body will result in a myriad of serious conditions, and life cannot be sustained without it. view more (2007-07-24)
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