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Cathepsin B increases apoptosis in fulminant hepatic failure
The traditional view is that hepatocyte necrosis is the main feature of fulminant hepatic failure, but increasing evidence implicates a dominant role for hepatocyte apoptosis in this pathogenesis. view more (2009-03-20)
Is hepatic differentiation of embryonic stem cells induced by valproic acid and cytokines?
Embryonic stem (ES) cells, known for their capacity to proliferate indefinitely and differentiate into almost all types of cells including hepatocytes, have raised the hope of cellular replacement therapy for liver failure. view more (2009-11-18)
May hepatic granulomas be part of the histological spectrum of chronic hepatitis C?
While older large series of patients with hepatic granulomas have found sarcoidosis and tuberculosis to be the most common causes of hepatic granulomas, recent works have noted some patients with chronic hepatic C and hepatic granulomas and no other obvious associations. view more (2008-12-29)
Antifibrotic effects of green tea
Several studies have shown that lipid peroxidation stimulates collagen production in fibroblasts and hepatic stellate cells (HSC), and plays an important role in the development of liver fibrosis. view more (2009-11-18)
Why could prednisolone suppress the hepatic ischemia-reperfusion injury?
Hepatic ischemia-reperfusion injury is a serious complication but unavoidable problem in liver surgery including liver transplantation and hepatic resection. view more (2008-10-08)
Melatonin may be served as a potential anti-fibrotic drug
In China, the incidence of liver cirrhosis is still high. Liver cirrhosis results from fibrosis. If treated properly at fibrosis stage, cirrhosis can be prevented. view more (2009-03-31)
Large congenital and solitary intrahepatic arterioportal
A case report to be published on April 7, 2009 in the World Journal of Gastroenterology reported incidental findings of a large and solitary congenital APF in a 73-year-old woman. view more (2009-04-15)
Medication effective for acute liver failure in early stages of disease
The antidote for acute liver failure caused by acetaminophen poisoning also can treat acute liver failure due to most other causes if given before severe injury occurs, UT Southwestern Medical Center researchers and their colleagues at 21 other institutions have found. view more (2009-10-08)
Beyond liver transplants: Acutely damaged livers may be repaired via transplanted hepatocytes
A research team from the National Taiwan University Hospital has evaluated the efficiency of transplanted hepatocyte (liver) cells in animal models severely damaged by two kinds of chemical toxicity to see whether and how transplanted hepatocytes were able to efficiently repopulate the toxin-induced, severely damaged livers. view more (2010-02-02)
Is 31P MRS a useful tool for evaluating early acute hepatic radiation injury?
Acute hepatic radiation injury could lead to necrosis of hepatocytes, fatty degeneration and hepatic fibrosis. At the present, the gold standard test is liver biopsy. view more (2009-06-24)
Vascular and biliary complications after liver transplant can be reliably diagnosed when using CE-US
Contrast-enhanced ultrasound (CE-US) after a liver transplant is highly accurate in showing vascular as well as biliary complications, according to a recent study. view more (2007-05-07)
Attention: Extra-hepatic manifestation of hepatitis C virus infection
In 1994, the team of Tchernev and Petrova from Alexandrovska Hospital in Sofia examined a female patient with liver cirrhosis caused by chronic Hepatitis C virus (HCV). view more (2008-01-17)
Spontaneous liver rupture in a patient with peliosis hepatis
Peliosis hepatis (PH) is a rare pathological entity. PH varies from minimal asymptomatic lesions to larger massive lesions that may present with cholestasis, liver failure, portal hypertension, avascular mass lesion, or even spontaneous rupture. view more (2009-12-09)
New MU Study Indicates that Exercise Prevents Fatty Liver Disease
It's easy to go to the gym on a regular basis right after a person buys the gym membership. It's also easy to skip the gym one day, then the next day and the day after that. A new University of Missouri study indicates that the negative effects of skipping exercise can occur in a short period. view more (2008-10-30)
An effective strategy for inhibition of cirrhosis
In China, the incidence of liver cirrhosis is still high, although new therapeutic approaches have recently been proposed, there is no established therapy for liver fibrosis, and Authors investigated the prevention effects of Chinese Medicine Qianggan-Rongxian Soup on liver fibrosis induced by DMN in rat. view more (2008-09-25)
Sequential TACE and cryosurgery can improve survival times for patients with HCC?
Hepatocellular carcinoma (HCC)--a liver cancer--is recognized as one of the most common cancers in the world that disproportionately affects Southeast Asians and Africans. view more (2009-08-12)
A potential therapeutic agent for hepatic fibrosis
Accumulating evidence suggests that connective tissue growth factor (CCN2) plays a central role in fibrotic conditions in many organ systems. view more (2009-08-26)
How to effectively avoid many common complications and liver damage in bile duct exploration?
Micro-wound operation is becoming the trend in surgery in the 21st century and laparoscopic surgery is regarded as an important component of micro-wound surgery. view more (2008-03-13)
A potential therapeutic strategy for hepatic failure
Fulminant hepatic failure is a serious clinical disease and may threaten the life of patients. However, because of the damage of mass liver cells, the organ function is often irreversible due to the liver cell degeneration, swelling, or apoptosis. Thus, to supply new sources of functional liver cells is a valuable choice for these patients. view more (2009-03-31)
The use of stem cells in regenerative medicine may also be detrimental for health
The use of stem cells in regenerative medicine is not always beneficial for human health, it may even be harmful according to a work done by the University of Granada and University of León. Scientists have demonstrated that transplantation of human mononuclear cells isolated from umbilical cord blood exerted a deleterious effect in rats... view more... (2009-11-13)
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