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Hepatocellular Carcinoma Current Events | Hepatocellular Carcinoma News | 7

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Study says normal but out-of-control enzyme may be culprit that signals some cells to become cancer
Working with human colorectal cancer cells, a University of Minnesota team, led by cancer biologists Zigang Dong and Ann Bode, has found the potential culprit among a network of enzymes that relay signals inside cells to regulate such functions as cell growth, cancer development and programmed cell death.   view more (2007-08-01)

OHSU researcher develops first animal model to treat devasting head and neck cancers
An Oregon Health & Science University Cancer Institute research laboratory has developed a novel mouse model designed specifically to study the often devastating head and neck squamous cell cancers.   view more (2006-05-16)

Genetic breakdown in Fanconi anemia may have link to HPV-associated cancer
A genetic malfunction that causes DNA instability in people with the blood disorder Fanconi anemia may put them at high risk for squamous cell carcinomas linked to human papillomavirus (HPV), according to a study posted online ahead of print by Oncogene.   view more (2008-12-04)

Potential skin cancer breakthrough tested at Scottsdale Healthcare published today in New England Journal of Medicine
A study published today in the New England Journal of Medicine reports a potential new investigational therapy for advanced and metastatic basal cell skin cancer tested at the Virginia G. Piper Cancer Center at Scottsdale Healthcare and other sites appears to demonstrate tumor shrinkage and limited side effects in patients.   view more (2009-09-03)

Senescence in liver cells is found by CSHL scientists to help limit acute tissue damage
Although post-reproductive life in humans is often associated with decline and a loss of powers, an analogous state in certain cells -- called senescence -- is proving to be one of ironic potency. Scientists at Cold Spring Harbor Laboratory (CSHL) today reported that a particular class of senescent liver cells orchestrates a sequence of events in... view more... (2008-08-22)

Breakthrough model for human cancer may improve development of cancer drugs; study in PNAS
AVEO Pharmaceuticals, Inc., a biopharmaceutical company leveraging breakthrough discoveries in cancer biology to discover, develop and commercialize targeted oncology therapies, today announced findings from its novel human-in-mouse (HIM) cancer model system, in which AVEO successfully created invasive human tumors from primary human breast tissue... view more... (2009-04-07)

Imiquimod, an immune response modifier, is dependent on the OGF-OGFr signaling pathway
Researchers at The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have discovered that the efficacy of imiquimod, a clinically important immune response modifier with potent antiviral and antitumor activity, is dependent on the Opioid Growth Factor (OGF)-OGF receptor (OGFr) axis for its action.   view more (2008-07-28)

Candidate markers for gastric cancer
The sequencing of the human genome has opened the door for proteomics by providing a sequence-based framework for mining proteomes.   view more (2008-10-29)

UT Southwestern researchers refocus studies on patients with HIV, hepatitis
As HIV patients live longer thanks to advanced therapies, researchers are looking for better ways to treat accompanying maladies such as hepatitis that traditionally were not emphasized.   view more (2006-10-12)

New Test May Predict Breast Cancer Metastasis
Researchers at NewYork-Presbyterian Hospital/Weill Cornell Medical Center have identified a new marker for breast cancer metastasis called TMEM, for Tumor Microenvironment of Metastasis.   view more (2009-03-30)

Roadkill study could speed detection of kidney cancer
Large-scale data mining of gene networks in fruit flies has led researchers to a sensitive and specific diagnostic biomarker for human renal cell carcinoma, the most common type of kidney cancer.   view more (2009-01-27)

Edible vaccine for Hepatitis B
Edible Vaccines may play a big part in the future for protection against Hepatitis B infection. Professor Yasmin Thanavala, from Roswell Park Cancer Institute, USA, describes her research at the British Society for Immunology's Congress 2000 in Harrogate today (Wednesday 6 December 2000). The hepatitis B virus has infected more than 2 billion... view more... (2000-12-01)

Over-diagnosis Of Liver Failure After Paracetamol Poisoning?
Danish authors of a Research letter in this week's issue of THE LANCET suggest that there is the potential for clinicians to mistakingly diagnose liver failure after moderate paracetamol poisoning by relying solely on the measurement of one diagnostic marker. The use of acetylcysteine after paracetamol poisoning is of known therapeutic benefit;... view more... (2002-10-09)

Keyhole Surgery For Colorectal Cancer Offers Same Prognosis As Conventional Surgery (p 1187)
Laparoscopy ('keyhole surgery') for colorectal cancer could be the future treatment of choice after results of a study from Hong Kong in this week's issue of THE LANCET show how it is associated with a similar 5-year survival outcome and more favourable recovery time than conventional surgery. Colorectal cancer is one of the commonest forms of... view more... (2004-04-07)

A rigorous method for liver biopsy
Liver biopsy is still considered the gold standard for grading, staging and "stad-ging" the chronic liver disease. In addition, it remains a primary source for acquiring new knowledge on the liver pathology.   view more (2009-01-05)

Regulation of cell proliferation by the OGF-OGFr axis is dependent on nuclear localization signals
Researchers at The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have discovered that the efficacy of the Opioid Growth Factor (OGF, [Met5]-enkephalin), a clinically important antitumor agent, is dependent on nucleocytoplasmic translocation and reliant on the integrity of nuclear localization signals in the OGF receptor... view more... (2009-04-23)

'Treatment disconnect' in kidney cancer: Rising mortality despite more small tumors, more surgery
The rising incidence of kidney cancer may be due to an increase in the number of small, treatable kidney tumors.   view more (2006-09-20)

A new insight on ethanol-induced gastric mucosa injury
Many people all over the world indulge themselves in drinking, which is correlated to a wide spectrum of medical, psychological, behavioral, and social problems.   view more (2008-10-24)

HtrA1 and resistance to chemotherapy in ovarian and gastric cancers
While many cancer patients initially have a favorable response to chemotherapy for the treatment of solid tumors, resistance to treatment often develops.   view more (2006-06-09)

New study resolves the mysterious origin of Merkel cells
A new study resolves a 130-year-old mystery over the developmental origin of specialized skin cells involved in touch sensation.   view more (2009-09-28)
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