Hereditary Liver Diseases Current Events | Hereditary Liver Diseases News | 11
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Hyperactive immune resistance brings blindness in old age
Age-dependent macular degeneration (AMD) is the commonest cause of blindness in the western industrialised nations. Hereditary changes in the regulation of the immune system influence the risk of contracting AMD. view more (2008-07-25)
Transplanted liver cells function in older animals but do not proliferate as much as in younger ones
When things go right, transplanted healthy liver cells transplanted by infusion or injection will find their way to the liver, integrate into the damaged tissue, start proliferating, and take over the liver's work of helping with digestion and removing waste products and worn-out cells from the blood. view more (2009-04-20)
New toxicity test could cut animal testing
To test whether chemicals are toxic to humans, researchers need to use liver cells that have been freshly harvested from mice or other mammals. A new collection of stable cell lines, described in BMC Biotechnology this week, could reduce the numbers of animals needed in such experiments. The MMH-GH cell lines are derived from the liver cells of... view more... (2004-03-17)
USC study shows belly fat may affect liver function
A study by the University of Southern California (USC) suggests the release of lipids from abdominal fat, which drains directly to the liver, increases overnight, providing additional insight as to how abdominal fat is associated with type 2 diabetes risk. The results of the study were presented at an oral session Monday, June 9 at the American... view more... (2008-06-10)
Researchers estimate significant fatty liver disease in children
Until now little was known about the prevalence of non-alcoholic fatty liver disease (NAFLD) in children. view more (2006-10-02)
Antibody retards growth and induces death in liver cancer cells
Researchers from the University of Pittsburgh School of Medicine report a significant new advance in the search for an effective treatment for human liver cancer in the July issue of Molecular Cancer Therapeutics. view more (2007-07-12)
Radiation, chemotherapy with liver transplant improves cancer survival
A new treatment for patients with a type of bile duct cancer promises a greater chance at survival by combining radiation, chemotherapy and liver transplantation, Mayo Clinic physicians report in the September issue of the Annals of Surgery. view more (2005-09-12)
Low-fat diet helps genetically predisposed animals avoid liver cancer
In a study comparing two strains of mice, one susceptible to developing cancer and the other not, researchers found that a high-fat diet predisposed the cancer-susceptible strain to liver cancer, and that by switching to a low-fat diet early in the experiment, the same high-risk mice avoided the malignancy. view more (2009-06-12)
Coffee drinking associated with lower risk for alcohol-related liver disease
Drinking coffee may be related to a reduced risk of developing the liver disease alcoholic cirrhosis. view more (2006-06-13)
Study shows liver an excellent target for cancer gene therapy using viral vectors
A featured paper in the February 14 issue of Nature Cancer Gene Therapy demonstrates that cancer cells in the liver are excellent targets for gene therapy using adenoviral vectors, based upon a fundamental new understanding of the differences between cancerous and normal liver cells. view more (2007-02-15)
Feedback loop found that could forestall liver disease
Researchers at UT Southwestern Medical Center have discovered that the small intestine communicates with the liver to control the production of bile acids-a finding that has great medical implications in treating people at risk for certain types of liver disease. view more (2005-10-12)
Fatty acids and caveolin-1 are essential in liver regeneration
Liver regulates lipid, carbohydrate and protein metabolism. It also segregates a number of proteins and enzymes, and eliminates toxic substances from the organism. Liver regeneration is a mostly unknown process at a molecular level, although it is essential for the good functioning of the liver, and indispensable in order to carry out some... view more... (2006-09-19)
Early-onset obesity in father linked to increased potential for liver disease in child
A history of early-onset paternal obesity increases the odds of elevated liver enzyme levels in offspring and points to the potential for a genetic link between obesity and liver disease, according to a study in Gastroenterology, the official journal of the American Gastroenterological Association (AGA) Institute. view more (2008-04-01)
Developing a safer form of acetaminophen
Scientists in Louisiana are reporting development of a process for producing large batches of a new and potentially safer form of acetaminophen, the widely used pain-reliever now the source of growing concern over its potentially toxic effects on the liver. view more (2009-07-16)
Transfusion-free surgical program reduced use of blood products for all liver transplant patients
Development of a transfusion-free surgical program for Jehovah's Witness patients undergoing liver transplantation also has helped reduce the overall use of blood products for non-Jehovah's Witnesses undergoing the procedure. view more (2006-09-19)
3-Dimensionally Images In Magnetic Resonance
In the near future, images obtained from magnetic resonance will be common. The aim of the TRAC project is to be able to see internal organs 3-dimensionally using a non-invasive technique. Currently images of the liver are being worked with, but it is hoped that the technique will be useful for any internal structure or tissue. Vicomtech is one of... view more... (2004-06-15)
The natural history of 'healthy-HCV carriers'
A normal liver is observed in about 10% of HCV infected patients and the natural history of theses so-called "healthy-HCV carriers" is not fully defined. view more (2008-09-24)
Can liver cirrhosis be partially cured?
The diffusion of hepatitis C virus infection worldwide is astonishing. Liver cirrhosis is present in at least 10-20% of these infected patients, with highly increasing health care and emotional costs. view more (2007-10-11)
Tiny radioactive spheres effectively treat cancer that has spread to the liver
Placing tiny radioactive spheres directly into the liver through its blood supply halted growth of tumors that had spread to the organ in 71 percent of patients tested in a small clinical trial, researchers from Mayo Clinic Jacksonville report. view more (2007-10-30)
First human gets new antibody aimed at hepatitis C virus
Building upon a series of successful preclinical studies, researchers at MassBiologics of the University of Massachusetts Medical School (UMMS) today announced the beginning of a Phase 1 clinical trial, testing the safety and activity of a human monoclonal antibody they developed that can neutralize the Hepatitis C virus (HCV). view more (2009-08-07)
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