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Probiotic bacteria can induce monocyte-derived dendritic cells maturation?
Probiotic bacteria are widely used to relieve the symptoms of many disorders such as inflammatory bowel syndrome, diarrhea, and allergies. Probiotic mixtures have also been found to reduce the symptoms of diarrhea.   view more (2008-09-25)

Novel mouse gene reduces major pathologies associated with Alzheimer's disease
A new study reveals that a previously undiscovered mouse gene reduces the two major pathological perturbations commonly associated with Alzheimer's disease (AD).   view more (2009-11-12)

Study raises questions about prostate cancer therapies targeting IGF-1
Therapies under development to treat prostate cancer by inhibiting the ability of insulin-like growth factor (IGF-1) to activate its target receptor could have unexpected results especially if a major tumor suppressor gene - p53 - is already compromised, according to new research by investigators at Fred Hutchinson Cancer Research Center.   view more (2008-05-01)

Reduced insulin in the brain triggers Alzheimer's degeneration
By depleting insulin and its related proteins in the brain, researchers at Rhode Island Hospital and Brown Medical School have replicated the progression of Alzheimer's disease - including plaque deposits, neurofibrillary tangles, impaired cognitive functioning, cell loss and overall brain deterioration - in an experimental animal model.   view more (2006-03-23)

A potential approach to treatment of hepatitis B virus infection
Eukaryotic cells employ multiple strategies of checkpoint signaling and DNA repair mechanisms to monitor and repair damaged DNA.   view more (2008-09-10)

Barrow researchers identify new brain receptor, possible target for Alzheimer's treatment
Barrow Neurological Institute researchers have identified a novel receptor in the brain that is extremely sensitive to beta-amyloid peptide (AB) and may play a key role in early stages of Alzheimer's disease.   view more (2009-07-17)

When is a stem cell not really a stem cell?
Working with embryonic mouse brains, a team of Johns Hopkins scientists seems to have discovered an almost-too-easy way to distinguish between "true" neural stem cells and similar, but less potent versions.   view more (2007-08-27)

The hormone of darkness: melatonin could hurt memory formation at night
What do you do when a naturally occurring hormone in your body turns against you? What do you do when that same hormone - melatonin - is a popular supplement you take to help you sleep? A University of Houston professor and his team of researchers may have some answers.   view more (2007-11-16)

Protein linked to mental retardation controls synapse maturation, plasticity, CSHL team finds
A team of neuroscientists at Cold Spring Harbor Laboratory (CSHL) has demonstrated the mechanism by which a signaling protein found throughout the brain controls the maturation and strength of excitatory synapses, the tiny gaps across which the majority of neurons communicate.   view more (2009-06-02)

Cell signaling discovery yields heart disease clues
A pulsing heart cell is giving Oregon Health & Science University researchers insight into how it sends and receives signals, and that's providing clues into how heart disease and other disorders develop.   view more (2005-09-23)

Cell signaling discovery yields heart disease clues
A pulsing heart cell is giving Oregon Health & Science University researchers insight into how it sends and receives signals, and that's providing clues into how heart disease and other disorders develop.   view more (2005-09-26)

Chemical signaling helps regulate sensory map formation in the brain
Researchers from the University of Chicago have uncovered an important mechanism used by the developing brain to pattern nerve connections in the part of the brain that interprets visual signals.   view more (2006-01-05)

Edible bivalves as a source of human pathogens: signals between vibrios and the bivalve host.
Clams, mussels and oysters are important vehicles for the transmission of enteric diseases when consumed raw or undercooked. Vibrio species, including human pathogens, are particularly abundant in bivalve tissues, where they can persist even after cleaning procedures, thus representing a potential risk for human health. Although different... view more... (2005-05-25)

Experimental drug lets B cells live and lymphoma cells die
An investigative drug deprived non-Hodgkin lymphoma cells of their ability to survive too long and multiply too fast, according to an early study published recently in the journal Experimental Hematology.   view more (2009-09-22)

St. Jude finds signaling system that halts the growth of a childhood brain cancer
A discovery by St. Jude Children's Research Hospital scientists suggests a safer way to treat medulloblastoma, a rare but often fatal childhood brain tumor. The group found that one of the brain's signaling pathways inhibits the growth of the highly aggressive cancer cells.   view more (2008-03-17)

Key mechanism found that promotes spread of malignant melanoma
Researchers at Northwestern University have discovered a key signaling mechanism that may promote the ability of highly aggressive malignant melanoma cells to metastasize, or spread from a primary tumor to distant sites within the body.   view more (2005-11-01)

That '4 hour erection': new discovery may help prevent a complication of priapism
For men coping with painful erections lasting for long periods of time, or priapism, new research published online in The FASEB Journal (http://www.fasebj.org) offers hope.   view more (2009-10-27)

Researchers at Illinois explore queen bee longevity
The queen honey bee is genetically identical to the workers in her hive, but she lives 10 times longer and - unlike her sterile sisters - remains reproductively viable throughout life.   view more (2007-05-09)

Possible birthplace of malignant brain tumors identified
Researchers have found that abnormal stimulation of a cellular trigger that normally regulates replenishment of brain cells in adults causes invasive tumor-like growths in mice.   view more (2006-07-20)

St. Jude finds molecule that could improve cancer vaccines and therapy for other diseases
Investigators at St. Jude Children's Research Hospital have discovered a new signaling molecule that prevents immune responses from running amok and damaging the body.   view more (2007-11-26)
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