Hippo Signaling Current Events | Hippo Signaling News | 3
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Reward-stress link points to new targets for treating addiction
Rewarding and stressful signals don't seem to have much in common. But researchers studying diseases ranging from drug addiction to anxiety disorders are finding that the brain's reward and stress signaling circuits are intertwined in complex ways. view more (2008-12-17)
2-drug combination appears safe and active in metastatic kidney cancer
Fox Chase Cancer Center investigators report that a two-drug blockade of mTOR signaling appears safe in metastatic kidney cancer in a phase I trial. view more (2009-06-01)
What makes stem cells tick?
Investigators at the Burnham Institute for Medical Research (Burnham) and The Scripps Research Institute (TSRI) have made the first comparative, large-scale phosphoproteomic analysis of human embryonic stem cells (hESCs) and their differentiated derivatives. view more (2009-08-07)
Mechanism of nicotine's learning effects explored
While nicotine is highly addictive, researchers have also shown the drug to enhance learning and memory—a property that has launched efforts to develop nicotine-like drugs to treat cognitive deficits in Alzheimer's and Parkinson's diseases, schizophrenia, and attention-deficit/hyperactivity disorder. view more (2007-04-05)
New research identifies gene important for nicotine's effects on the brain
New research identifies an important gene that influences several aspects of nicotine-induced behaviors in the brain. The study, funded by National Institutes of Drug Abuse, was presented today at the American College of Neuropsychopharmacology's Annual Meeting. view more (2006-12-06)
Einstein researchers discover gene mutations linked to longer lifespans
Mutations in genes governing an important cell-signaling pathway influence human longevity, scientists at the Albert Einstein College of Medicine of Yeshiva University have found. view more (2008-03-05)
More reliable and secure telecommunications via the Internet
Professor Anna Brunström, Karlstad University, is heading a research project that will lead to more reliable and secure telecommunications via the Internet. Reliability is an important aspect when telephony moves over to the Internet, so-called IP-telephony. Today there are three different nets: for telephony, for the Internet, and for... view more... (2005-03-15)
Another reason to avoid high-fat diet -- it can disrupt our biological clock
Indulgence in a high-fat diet can not only lead to overweight because of excessive calorie intake, but also can affect the balance of circadian rhythms - everyone's 24-hour biological clock, Hebrew University of Jerusalem researchers have shown. view more (2008-12-29)
Scientists take next step in understanding potential target for Ovarian cancer treatment
A traffic cop protein in the cell may have an even more important role: transporting a messenger protein that tells components in the nucleus to stop cell growth. The discovery of this additional role may lead to diagnostic tools and earlier treatments for ovarian cancer. view more (2007-07-17)
Manipulating Cell Receptor Alters Animal Behavior
Researchers at the University at Buffalo and the University of Pennsylvania were the first to demonstrate that two intracellular events, both stimulated by the same cell receptor, can provoke different behaviors in mammals. view more (2006-03-22)
Immunity in social amoeba suggests ancient beginnings
Finding an immune system in the social amoeba (Dictyostelium discoideum) is not only surprising but it also may prove a clue as to what is necessary for an organism to become multicellular, said the Baylor College of Medicine researcher who led the research that appears today in the journal Science. view more (2007-08-03)
UCSF study points to link to neurodegenerative disease target
The findings are relevant for ongoing research in identifying causes and developing treatments for neuromuscular neurodegenerative diseases in humans, such as amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. view more (2005-09-02)
Compound reveals new link between signaling protein and cell migration
University of Illinois at Chicago researchers report that a protein that regulates key signaling pathways in cells also plays a role in controlling the active movement or migration of cells. view more (2005-09-26)
Certain anticancer agents could be harmful to patients with heart disease
A set of promising new anticancer agents could have unforeseen risks in individuals with heart disease, suggests research at Washington University School of Medicine in St. Louis. view more (2008-06-24)
Certain diseases, birth defects may be linked to failure of protein recycling system
A group of signaling proteins known as Wnt - which help build the human body's skin, bone, muscle and other tissues - depend on a complex delivery and recycling system to ensure their transport to tissue-building cell sites, according to a study at Cincinnati Children's Hospital Medical Center. view more (2007-12-21)
Making sense of the human genome: researchers characterize a crucial family of signaling proteins in the human genome
In this month's Genome Biology, Mitch Kostich and colleagues from the Schering-Plough Research Institute (NJ, USA) have identified and mapped an important group of molecules known as protein kinases. These molecules are central to the communication of information both within and between cells, in a process known as cell signaling. Defective... view more... (2002-08-23)
Cellular molecule spurs growth of prostate cancer
University of North Carolina at Chapel Hill scientists have identified a molecule that stimulates the aggressive growth of prostate cancer. view more (2005-11-29)
New genetic mutations found that may cause cleft lip/palate
University of Iowa researchers and collaborators have identified new genetic mutations that likely cause the common form of cleft lip and palate. view more (2007-03-06)
Research uncovers new steps on pathway to enlarged heart
Researchers have new insight into the mechanisms that underlie a pathological increase in the size of the heart. The research, published by Cell Press in the October 24th issue of the journal Molecular Cell, may lead to the development of new strategies for managing this extremely common cardiac ailment that often leads to heart failure. view more (2008-10-24)
Protein maintains cross talk between cells that control hair growth
Genes, it turns out, are only as active as the signals that turn them on and off. Now scientists from Rockefeller University and the Howard Hughes Institute have identified the signaling molecule that ratchets up and clamps down the activity of key genes in dermal papilla, a type of skin cell whose unique collection of proteins ultimately instruct... view more... (2008-02-15)
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