Hippo Signaling Current Events | Hippo Signaling News | 4
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Case Western Reserve research finds that the lack of specific gene plays role in autism
It is estimated that three to six out of every 1,000 children in the United States have autism - and the number of diagnosed cases is rising. view more (2009-02-09)
Global signaling study suggests cancer link to protein promiscuity
When found at abnormally high concentrations, two proteins implicated in many human cancers have the potential to spur indiscriminate biochemical signaling inside cells. view more (2005-11-17)
Depression linked to previously unknown dopamine regulator
Researchers from Harvard Medical School have found a molecule that is unexpectedly involved in dopamine signaling, and in a manner that supports the potential of dopamine as an alternative target for treating depression. view more (2005-07-29)
Case Western Reserve University researchers find protein associated with brain cell death
Neuroscientists at the Case Western Reserve University School of Medicine have found evidence of which protein in the brain's immune cells triggers a cascade of reactions that produces unregulated free radical production that eventually leads to the neural cell death found in Alzheimer's disease. view more (2006-07-19)
Researchers identify protein pathway involved in Parkinson disease development
Scientists have found a novel signaling pathway in cells that is altered by genetic mutations recently identified in Parkinson disease development. view more (2007-06-19)
New insight into an old reaction: Adenylylation regulates cell signaling
A new study reveals the importance of adenylylation in the regulation of cell signaling from bacteria to higher organisms. view more (2009-04-10)
Gene signature helps predict breast cancer prognosis
Vanderbilt-Ingram Cancer Center researchers have uncovered a gene signature that may help predict clinical outcomes in certain types of breast cancer. view more (2009-05-20)
MIT: Computer model reveals cells' inner workings
After spending years developing a computational model to help illuminate cell signaling pathways, a team of MIT researchers decided to see what would happen if they "broke" the model. view more (2008-10-17)
Model offers new understanding of cell signaling
Looking for answers in the bright light of day, rather than the confined beam of a street light at night. That's how University of Michigan researcher Sofia Merajver, M.D., Ph.D., describes the power of a new mathematical model that could have far-reaching impact on how scientists study cellular signaling pathways. view more (2008-03-25)
From lung to gut - the Wnt signaling pathway transforms cell fate
Researchers have uncovered a cellular mechanism that can alter the fate of progenitor cells that normally generate the lung, causing them to create gut cells instead. The findings, which are published this week in the top-tier Open Access journal, Journal of Biology, could help researchers hoping to use adult stem cells for therapeutic purposes.... view more... (2004-06-03)
Plants on steroids: Key missing link discovered
Researchers at the Carnegie Institution's Department of Plant Biology have discovered a key missing link in the so-called signaling pathway for plant steroid hormones (brassinosteroids). view more (2009-09-09)
Similar stem cells in insect and human gut
Scientists at the Carnegie Institution's Department of Embryology have found that adult fruitflies have the same stem cells controlling cell regulation in their gut as humans do. view more (2005-12-08)
Fruit flies show how salmonella escapes immune defenses
Salmonella are wily and obnoxious bacterial invaders--escape artists capable of evading multiple immune responses and causing a harsh and debilitating intestinal infection. view more (2008-04-17)
Research uncovers signaling pathways related to brain-immune system links
New research on signaling pathways in immune cells bolsters evidence of connections between the central nervous system and the immune system. view more (2006-05-16)
Chemical genomic screening identifies novel therapeutic strategies for cancer
A sophisticated new chemical genetic screening strategy that serves as a tool for identifying anticancer compounds may significantly enhance the drug discovery process. view more (2006-09-29)
Stopping the clock: Genetics of tumor latency in skin cancer
Dr. Anthony E. Oro and colleagues (Stanford University) have identified two key Gli protein degradation signals that directly affect tumor latency in a mouse model of human skin cancer. view more (2006-01-20)
Structure of key enzyme in plague bacterium found
Researchers at the National Institute of Standards and Technology (NIST) have solved the structure of a key enzyme from the bacterium responsible for plague, finding that it has a highly unusual configuration. The results may shed light both on how the bacterium kills and on fundamental cell signaling processes. view more (2006-08-21)
Starting over: Wnt reactivates dormant limb regeneration program
Chop off a salamander's leg and a brand new one will sprout in no time. But most animals have lost the ability to replace missing limbs. Now, a research team at the Salk Institute for Biological Studies has been able to regenerate a wing in a chick embryo - a species not known to be able to regrow limbs-suggesting that the potential for such... view more... (2006-11-20)
LSUHSC researcher identifies new target to prevent fatal flu lung complication
Research led by Dr. Jay Kolls, Professor and Chairman of Genetics at LSU Health Sciences Center New Orleans, has identified a therapeutic target for acute lung injury resulting in acute respiratory distress syndrome, a highly fatal complication of influenza infection. view more (2009-09-30)
Study uncovers significant functional differences of novel estrogen receptor
Because of these differences, this new estrogen receptor could become an important therapeutic target and may play a further signaling role in other estrogen target tissues, including uterus and prostate tissues. view more (2006-06-09)
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